1990 Fiscal Year Final Research Report Summary
Physiological Function of Polyamines Which are Covalently Linked to Peptidoglycan in Bacteria
| Project/Area Number |
01560112
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| Research Category |
Grant-in-Aid for General Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Research Field |
発酵・醸造
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| Research Institution | TOHOKU UNIVERSITY |
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Principal Investigator |
KAMIO Yoshiyuki Dept. of Agric. Chemistry, Associate Professor, 農学部, 助教授 (00109175)
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| Project Period (FY) |
1989 – 1990
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| Keywords | polyamine / Cadaverine / Spermidine / peptidoglycan / リピド中間体:ポリアミン転移酵素 |
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| Research Abstract |
ABSTRACT
Polyamine covalently linked to the cell wall peptidoglycan was found to occur in strictly anaerobic lactate fermenting bacteria. The strains included Selenomonas ruminantiom, S. sputigena, Veillonellaalcalescens, V parvula, Anaerovibrio lipolytica and Megasphaera elsdenii.
In A. lipolytica, spermidine is linked covalently to the alpha-carboxylgroup of the peptidoglycan, while in other strains, putrescine and cadaverine are linked to the same group of the peptidoglycan. All the studied anaerobes containing polyamine linked to the peptidoglycan studied hitherto possessed neither phospatidylglvcerol, cardiolipin normurein lipoprotein in their envelopes. These microorganisms were resistant to monensin which is an ionophore for potassium iom.
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