1990 Fiscal Year Final Research Report Summary
Ultrastructural studies on the effects of hypergravity environment on the parathyroid glands in golden hamsters of different ages
| Project/Area Number |
01570007
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| Research Category |
Grant-in-Aid for General Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Research Field |
General anatomy (including Histology/Embryology)
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| Research Institution | Gifu University |
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Principal Investigator |
ISONO Hideo Gifu University, School of Medicine, Professor, 医学部, 教授 (50021358)
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| Project Period (FY) |
1989 – 1990
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| Keywords | Hypergravity / Hamster / Parathyroid gland / Aging / Pregnancy / Fetus / Electron microscopy |
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| Research Abstract |
The ultrastructure of the parathyroid glands of maternal, fetal, infantile, juvenile, adult and senile golden hamsters subjected to a hypergravity environment was studied. In the parathyroid glands of maternal and fetal, and 5-, 10- and 20-day-old, and 1- and 3-month-old golden hamsters exposed to ahypergravity environment, the Golgi complexes were significantly increased, and in 8-month-old animals exposed to a hypergravity environment appeared to be increased as compared to those of each control group. In addition, in centrifuged animals numerous prosecretory granules were observed in the Golgi areas and many secretory granules were located in the peripheral cytoplasm. The ultrastructure of the parathyroid glands of 14-month-old centrifuged animals resembled that of 14-month-old control animals.
These results suggest that the secretory activity of the parathyroid gland may be stimulated in maternal, fetal, infantile, juvenile and adult golden hamsters subjected to a hypergravity environment and may not be stimulated in senile animals subjected to a hypergravity environment.
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