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1992 Fiscal Year Final Research Report Summary

Studies on establishment of anesthetic method in Experimental animals.

Research Project

Project/Area Number 02304059
Research Category

Grant-in-Aid for Co-operative Research (A)

Allocation TypeSingle-year Grants
Research Field Laboratory animal science
Research InstitutionOkayama University

Principal Investigator

KURABAYASHI Yuzuru  Okayama University medical school, Associate professor., 医学部, 助教授 (90033373)

Co-Investigator(Kenkyū-buntansha) MAEZIMA Kazuyoshi  Keio University, Department of medical science, Professor., 医学部, 教授 (70051464)
NAMIOKA Shigero  Hokkaido University, Department of Veterinary science, Professor., 獣医学部, 教授 (10002297)
TAKEUCHI Akira  TOKYO University, Department of Agriculture science, Professor., 農学部, 教授 (90011874)
MITSUOKA Tomotari  Nippon Veterinary and Animal science University, department of Food science and, 食品工学科, 教授 (30157549)
KOSAKA Futami  Okayama University medical school, Professor emeritus., 医学部, 名誉教授 (00032847)
Project Period (FY) 1990 – 1992
KeywordsExperimental animals / Method of anesthesia / Animal welfare / Premedication / Anesthesia management / Post operative care / Method of pain relief / Anesthetic apparatus
Research Abstract

We were get a following results.
1). We were established method of anesthesia in experimental animals, for instance mouse, rat, hamster, guinea pig, rabbit and pigs.
2). It's method are make a critical commentary upon the anesthesiology, ethics and animal welfare. (1) And then it's a new method as pain relief in animal experimentation. (2) Also method of animal handling, fixation and selected sedative medicine, analgesics in premedication. (3) Selected (injectable and inhalation) anesthetics, determins of use doses in pre, during and post operative stage. (4) Development of Electronic control anesthetics vaporizing system (ECAVS) in small and middle size experimental animals.
3). It's new method are make a critical commentary upon the physiological and biochemistry, for example respiratory rate, pulse, body temperature, blood pressure, electro cardio graph (ECG), electro encepharo graph (EEG), concentration of inspiratory and expiratory anesthetics gases, pH, PCO_2, PO_2, HCO_3, O_2 SAT., base excess, total CO_2, O_2 content in blood were mesured.
4). It is established diffusing anesthetics method in each experimental animals.

  • Research Products

    (23 results)

All Other

All Publications (23 results)

  • [Publications] 倉林 譲: "バイオメディカルリサーチマニュアル はじめに(動物実験に必要な実験動物の麻酔法)" 株式会社養賢堂, 7 (1993)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 倉林 譲: "バイオメディカルリサーチマニュアル 実験動物の鎮静" 株式会社養賢堂, 10 (1993)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 倉林 譲: "バイオメディカルリサーチマニュアル 実験動物の鎮痛" 株式会社養賢堂, 9 (1993)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 小坂 二度見: "バイオメディカルリサーチマニュアル 動物実験に使用できる全身麻酔薬" 株式会社養賢堂, 7 (1993)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 倉林 譲: "バイオメディカルリサーチマニュアル 実験動物福祉を考慮した局所麻酔薬" 株式会社養賢堂, 14 (1993)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 小林 嘉代: "バイオメディカルリサーチマニュアル マウスの全身麻酔法" 株式会社養賢堂, 32 (1993)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 田村 弘: "バイオメディカルリサーチマニュアル モルモットの全身麻酔法" 株式会社養賢堂, 33 (1993)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 黒澤 努: "バイオメディカルリサーチマニュアル ウサギの全身麻酔法" 株式会社養賢堂, 57 (1993)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] YUZURU, KURABAYASHI: "Development of an electronic control anesthetics vaporizing system (ECAVS)." Okayama igakkai zasshi. 103, 3(1156). 427-434 (1991)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] YUZURU, KURABAYASHI: "Fundamental Knowledge for method of anesthesia in experimental animals , the necessity as establishment of anesthesia method in experimental animals." Laboratory Animal Technology and Science. 3, 3. 540-542 (1991)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] HIROSHI, TAMURA: "Fundamental knowledge for method of anesthesia in experimental animals, drugs and method of administration as a pre-anesthetic medication." Laboratory Animal Technology and Science. 3, 3. 543-548 (1991)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] TERUO, YAMADA: "Fundamental knowledge for method of anesthesia in experimental animals, general anesthetics and it's method." Laboratory Animal Technology and Science. 3, 3. 549-555 (1991)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] KAYO, KOBAYASHI: "Fundamental knowledge for method of anesthesia in experimental animals --- mouse, rat, guinea pig and rabbit." Laboratory Animal Technology and Science. 3, 3. 556-565 (1991)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] AKIRA, TAKEUCHI: "Fundamental knowledge for method of anesthesia in experimental animals, anesthetic method in middle size experimental animals --- dog, cat, pig." Laboratory Animal Technology and Science. 3, 3. 566-570 (1991)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] YUZURU, KURABAYASHI: "Hirokawa shoten, Anesthesia." Continuation, development of medical supplies. vol,1. 276-296 (1991)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] YUZURU, KURABAYASHI: "Yohkendo Co. ltd., Introduction ( Anesthesia method, necessity for animal experimentation in experimental animals )." Biomedical research manual. 7. (1993)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] YUZURU, KURABAYASHI: "Yohkendo Co. ltd., Sedation in experimental animals." Biomedical research manual. 10. (1993)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] YUZURU, KURABAYASHI: "Yohkendo Co. ltd., Analgesia in experimental animals." Biomedical research manual. 9. (1993)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] FUTAMI, KOSAKA: "Yohkendo Co. ltd., General anesthetics for usable animal experimentation." Biomedical research manual. 7. (1993)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] YUZURU, KURABAYASHI: "Yohkendo Co. ltd., Local anesthetics which consideration in experimental animal welfare." Biomedical research manual. 14. (1993)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] KAYO, KOBAYASHI: "Yohkendo Co. ltd., Method of general anesthesia in Mice." Biomedical research manual. 32. (1993)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] HIROSHI, TAMURA: "Yohkendo Co. ltd., Method of general anesthesia in guinea pigs." Biomedical research manual. 33. (1993)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] TSUTOMU, KUROSAWA: "Yohkendo Co. ltd., Method of general anesthesia in rabbits." Biomedical research manual. 57. (1993)

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 1994-03-24  

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