1992 Fiscal Year Final Research Report Summary
Neurochemical Research for the Molecular Mecharusm of Volatile Anesthetic Actions
| Project/Area Number |
02454363
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| Research Category |
Grant-in-Aid for General Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
麻酔学
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| Research Institution | The Jikei University School of Medicine |
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Principal Investigator |
TANIFUJI Yasumasa The Jikei University School of Medicine, Anesthesiology, Associate Professor, 医学部, 助教授 (00056847)
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| Co-Investigator(Kenkyū-buntansha) |
MIYANO Kazuko The Jikei University School of Medicine, Anesthesiology, Instructor, 医学部, 助手 (90209924)
KAZESHIMA Kazuyuki The Jikei University School of Medicine, Anesthesiology, Instructor, 医学部, 助手 (80185727)
MISHIMA Kimi The Jikei University School of Medicine, Anesthesiology, Instructor, 医学部, 助手 (70181873)
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| Project Period (FY) |
1990 – 1992
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| Keywords | striatum / dopamine / volatile anesthotics / neurotransmitter / MAC / microdialysis |
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| Research Abstract |
The effect of volatile anesthetics on dapaminergic nervous system by in vivo microdialysis.
(1) The effect of halathane dose on dopamine in rat striatum.
(2) Differential effects of four Kinds of volatile anesthetics on dopamine in rat striatum.
(3) The effect of the dopamine content in atriatum on the anesthetic requirement.
(4) The relationship between the changing MAC caused by agingand neurotransmitter, norepirephine, serotonin, and dopamine content in rat brain.
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