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1992 Fiscal Year Final Research Report Summary

Basic and clinical study of spinal instrumentation made of new artificial materials

Research Project

Project/Area Number 02670643
Research Category

Grant-in-Aid for General Scientific Research (C)

Allocation TypeSingle-year Grants
Research Field Orthopaedic surgery
Research InstitutionHokkaido University

Principal Investigator

SHIRADO Osamu  Hokkaido University Hospital, Instructor, 医学部附属病院, 助手 (20206296)

Co-Investigator(Kenkyū-buntansha) TADANO Shigeru  Hokkaido Univ. Faculty of Engineering, Associate Professor, 工学部, 助教授 (50175444)
KANEDA Kiyoshi  Hokkaido Univ. School of Med. Professor, 医学部, 教授 (60000957)
Project Period (FY) 1990 – 1992
Keywordsspinal instrumentation / artificial materials / biomaterials / trunk muscle / biomechanics
Research Abstract

Spinal instrumentations, which are made of stainless steel, play a significant role to stabilize the injured spines caused by trauma, tumors, degenerative diseases, and the other disorders. Those instrumentations have allowed patients to ambulate immediately after surgery. Thus, they can enjoy the good quality of life, even after big surgeries. Major disadvantages, however, are as follows; 1) Patients treated with spinal instrumentations (stainless steel) can not be examined with MRI (Magnetic Resonance Imaging), which is very useful in evaluating the neural tissues.:2) Spinal instrumentations, made of stainless steel, sometimes have to be removed two or three years after surgery. The purpose of this study are to evaluate the possibilities of spinal instrumentations, made of new artificial materials and to analyze the biomechanical properties of trunk muscle, which plays a important role after spinal stabilization surgery using spinal instrumentations. Results are as follows;
1) Biocomp … More atible new materials such as chitin, polylactic acid, biodegradable high-molecule polymer, can be used for spinal instrumentations. Mechanical strength of the above materials, however, is inadequate for clinical use as spinal instrumentations. Stronger bioactive materials are now being evaluated.
2) From our clinical studies, spinal instrumentation made of titanium is now one of the best biocompatible ones for clinical use.
3) Trunk muscle strength is weaker in the patients with various spinal disorders than in the healthy subjects. This was true in the trunk muscle endurance. New methods for examining trunk muscle endurance are developed, modified with Kraus-Weber test and Sorensen test. Moreover, patients have the weaker trunk muscles in terms of both concentric and eccentric contraction. Trunk muscle proved to be quite important tissue for stabilize the spinal column as dynamic stabilizer.
4) Characteristics of flexion-relaxation phenomenon became clear. This phenomenon occurred only in patients with low-back pain.
5) On the next step, newer materials for spinal instrumentations and characteristic of trunk muscle have to be more analyzed. Less

  • Research Products

    (22 results)

All Other

All Publications (22 results)

  • [Publications] 白土 修: "脊椎分離・すべり症に対するinstrument使用の必要性、厳密な適応、禁忌" Monthly Book Orthopaedisc. 6. 115-124 (1993)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Osamu SHIRADO: "Quantitative Histologic Study of the lnfluence of Anterior spinal lnstrumentation and Biodegradable Polymer on Lumbar Fusion After Corpectomy-A Canine Model." Spine. 17(7). 795-803 (1992)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Osamu SHIRADO: "Influence of Disc Degeneration on Mechanism of Thoracolumbar Burst Fractures." Spine. 17(3). 286-292 (1992)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Osamu SHIRADO: "Trunk-Muscle Strength During Cocentric and Eccentric Contraction:Acomparison Between Healthy Subjects and Patients with Chronic Low-Back Pain." J.of Spinal Disorders. 5(2). 175-182 (1992)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Osamu SHIRADO: "Trunk-Muscle Strength during Eccentric Contraction in Patients with Chronic Low-Back Pain." Orthop.Trans.(1993)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Osamu SHIRADO: "Biomechanical Evaluation of Methods of Posterior Stabilization of the Spine and Posterior Lumbar lnterbody Arthorodesis for Lumbosacral lsthmic Spondylolisthesis.A calf-Spine Model." J.B.J.S. 73(A). 518-526 (1991)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 白土 修: "In vivo animal modelを用いたspinal instrumentationの実験的研究." 別冊整形外科. 20. 8-11 (1991)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 白土 修: "胸・腰椎損傷の分類-Clinical biomechanicsと神経障害からinstrumentation手術適応の検討" OS NOW. 4. 40-51 (1991)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 白土 修: "体幹筋力に関する基礎的研究-特に収縮様式に着目して-" 整形外科バイオメカニクス. 12. 183-187 (1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 白土 修: "脊椎分離・すべり症に対するInstrument使用の必要性、厳密な適応、禁忌" Monthly Book Orthopaedisc. 6. 115-124 (1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 白土 修: "生検を用いた椎体切除後における脊柱前方固定術のX線学的および生体力学的研究" 整形外科バイオメカニクス. 11. 25-29 (1989)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Osamu Shirado: "Spinal instrumentation for isthmic spondylolisthesis(in Japanese)" Monthly Book Orthopaedics. 6. 115-124 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Osamu Shirado: "Quantitative Histologic Study of the Influence of Anterior spinal Instrumentation and Biodegradable Polymer on Lumbar Interobody Fusion After Corpectomy-A Canine Model." Spine. 17(7). 795-803 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Osamu Shirado: "Influence of Disc Degeneration on Mechanism of Thoracolumbar Burst Fractures." Spine. (17)3. 286-292 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Osamu Shirado: "Trunk-Muscle Strength During Cocentric and Eccentric Contraction: A comparison Between Healthy Subjects and Patients with Chronic Low-Back Pain." J. of Spinal Disorders. 5(2). 175-182 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Osamu Shirado: "Trunk Muscle Strength during Eccentric contraction in Patients with Choronic Low Back Pain." Orthop. Trans.(1993)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Osamu Shirado: "Biomechanical Evaluation of Methods of Posterior Stabilization of the Spine and Posterior Lumbar Interbody Arthorodesis for Lumbosacral Isthmic Spondylolisthesis. A call-Spine Model." J.B.J.S. 73(A). 518-526 (1991)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Osamu Shirado: "Treatment of isthmic spondylolisthesis with nerve root decompression and posterolateral fusion using Steffee transpedicular screw system.(in Japanese)" Bessatu Seikeigeka. 20. 127-130 (1991)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Osamu Shirado: "Experimental study of spinal instrumentation using in vivo animal model(in Japanese)" Bessatu Seikeigeka. 20. 8-11 (1991)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Osamu Shirado: "Classification of thoracolumbar spinal injuries(in Japanese)" OS NOW. 4. 40-51 (1991)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Osamu Shirado: "The study of trunk muscle strength based on contraction modes(in Japanese)" Orthopedic Biomechanics. 12. 183-187 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Osamu Shirado: "Radiographic and biomechanical study of anterior spinal reconstructive surgery following corpectomy in canine model.(in Japanese)" Orthopedic Biomechanics. 11. 25-29 (1989)

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 1994-03-24  

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