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1992 Fiscal Year Final Research Report Summary

Myocardial anisotropy and cardiac arrhythmias

Research Project

Project/Area Number 02807086
Research Category

Grant-in-Aid for General Scientific Research (C)

Allocation TypeSingle-year Grants
Research Field Circulatory organs internal medicine
Research InstitutionToyama Medical & Pharmaceutical University

Principal Investigator

FUJIKI Akira  Toyama Medical & Pharmaceutical University The 2nd Dept. of Internal Med., 医学部, 助手 (90181338)

Project Period (FY) 1990 – 1992
KeywordsAnisotropy / Arrhythmias / Ischemia
Research Abstract

The effects of acute ischemia on conduction velocites in the longitudinal (VL) and transverse (VT) fiber axis were determined from epicardial activation patterns, recorded with 48 bipolar electrodes on the left anterior and posterior canine ventricular wall. During the control state VL was greater than VT demonstrating anisotropic properties of cardiac muscle. During acute ischemia VL and VT were decreased from the control value and VT was decreased greater extent than VL resulting in an increase in VL/T in both anterior and posterior wall. This augumented anisotropic ventricular conduction may have some relation to the initiation of ventricular arrhythmias during acute ischemia.

  • Research Products

    (7 results)

All Other

All Publications (7 results)

  • [Publications] 藤木 明: "イヌ心筋異方向性電導に対する急性虚血の影響" 循環器. 27. 531-534 (1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 水牧 功一: "急性虚血時の心室細動発生における心筋異方向性電導の関与" 心臓. 24Supp15. 79-85 (1992)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Hiroshi TSUJI: "Quantitative relationship between atrial refractoriness and the dispersion of refractoriness in atrial fibrillation." PACE. 15. 403-410 (1992)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Fujiki A., et al.: "Effects of acute ischemia on anisotropic conduction in canice ventricular muscle." Junkankika. 27. 531-534 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Mizumaki K., et al.: "Anisotropic conduction and ventricular fibrillation in acute myocardial ischemia." Shinzo. 24(suppl 5). 79-85 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Tsuji H., et al.: "Quantitative relationship between atrial refractoriness and the dispersion of refractoriness in atrial vulnerability." PACE. 15. 403-410 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Mizumaki K., et al.: "Effects of acute ischemia on anisotropic conduction in canice ventricular muscle." PACE. (1993)

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 1994-03-24  

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