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[Publications] Mauxion,F.et.al.: "Comparison of constitutive and inducible transcriptional enhancement mediated by KB-related sequences:modulation of activity in B cells by human T cell leukemia virus type I tax gene" Proceedings of National Academy of Science USA. 88. 2141-2145 (1991)
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[Publications] Miyatake,S.et.al.: "Characterization of the mouse GM-CSF promoter:nuclear factors that interact with an element shared by three lymphokine genes:GM-CSF,IL-4,and IL-5" Molecular and Cellular Biology. 11. 5894-5909 (1991)
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[Publications] Kitamura,T.et.al.: "Expression cloning of human IL-3 receptor cDNA and reconstitution of high affinity receptors for human IL-3 and GM-CSF" Cell. 66. 1165-1174 (1991)
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[Publications] Tsuboi,A.et.al.: "A nuclear factor NFGM2,essential for induction of GM-CSF gene in response to T-cell activation:purification from T cell leukemia line Jurkat cell and relationship to NF-kB" International Immunology. 3. 807-817 (1991)
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[Publications] Nomura,N.et.al.: "Identification of eleven single strand initiation sequences(ssi) for priming of DNA replication in the F,R6K,R100 and ColE2 plasmids" Gene. 108. 15-22 (1991)
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[Publications] Arai,K.et.al.: "Cytokine network and regulation of inflammatory response" Excepta Medica. (1991)
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[Publications] Nishida,J.et.al.: "Definition of GC rich motif as regulatoy sequence of thehuman IL-3 gene:coordinate regulation of the IL-3 gene by CLE2/GC box of the GM-CSF gene in T cell activation" International Immunology. 3. 245-254 (1991)
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[Publications] Watanabe,S.et.al.: "Colony stimulating factors and cytokine receptor network" Current Opinion in Biotechnology. 2. 227-237 (1991)
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[Publications] Kitamura,T.et.al.: "Reconstitution of functional receptors for human granulocytemacrophage colony stimulating factor:requirement of the b subunit for signaling" Proceedings of National Academy of Science USA. 88. 5082-5086 (1991)
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[Publications] Schreurs,J.et.al.: "AIC2A is a component of the purified high affinity mouse IL-3 receptor:temperature-dependent modulation of AIC2A structure" International Immunology. 3. 1231-1242 (1991)
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[Publications] Ozu,M.et.al.: "Regulation of the IL-3 gene and structure and function of the IL-3 receptor" Advance in Neuroimmunology. 2. 32-52 (1992)
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[Publications] Wang,H.M.et.al.: "Structure of mouse IL-3 binding protein (AIC2A):Amino acid residues critical for IL-3 binding" Journal of Biological Chemistry. (1992)
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[Publications] Garret,K.P.et.al.: "The C-terminus of rat RAP30 is similar in sequence to region 4 of bacterial sigma factors and is required for function" submitted. (1992)
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[Publications] Hisatsune,T.et.al.: "A suppressive lymphokine derived from Ts clone 13G2 is IL-10" Lymphokine Research. (1992)
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[Publications] Miyajima A.et.al.: "Cytokine receptors and signal transduction" Annual Review of Immunology. 10. 295-331 (1992)
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[Publications] Abe,E.et.al.: "Eleven-base pair DNA sequence motif unique to human IL-4 gene confers responsiveness to T cell activation signals" Proceedings of National Academy of Science USA. (1992)
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[Publications] Ishihara,T.et.al.: "Molecular cloning and expression of a cDNA encoding the secretin receptor" EMBO J.10. 1635-1641 (1991)
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[Publications] Itoh,N.et al.: "The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis" Cell. 66. 233-243 (1991)
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[Publications] Chiba,S.et al: "Establishment and erythroid differentiation of a cytokinedependent humanleukemic cell line F-36:A parental line requiring granulocyte-macrophage colony-stimulating factor or interleukin-3,and a subline requiring erythropoietin" Blood. 78. 2261-2268 (1991)
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[Publications] Sasaki,K.et al.: "Identification of a solible GM-CSF binding protein in the supernatant of a human choriocarcinoma cell line" Biochem.Biophys.Res.Commun.
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[Publications] Taketazu,F.et al.: "IL-3 specifically inhibits GM-CSF binding to the higher affinity receptor" J.Cell.Physiol.146. 251-257 (1991)
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[Publications] Tanaka,T.et al.: "Stimulatory effects of granulocyte colony-stimulating factor on CFU-S differentiation and pre-CSF-S proliferation in mice" Blood. 77. 2597-2602 (1991)
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[Publications] Sugiyama,H.et al.: "V-ABL does not abolish IL-6 requirement by murine plasmacytoma cells" Int.J.Cancer. 48. 234-238 (1991)
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[Publications] Fukunaga,M.et al.: "Signal transduction mechanism of interleukin 6 in cultured rat mesangial cells" FEBS Letter. 285. 265-267 (1991)
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[Publications] Takenawa,J.et al.: "Enhanced expression of interleukin-6 in primary human renal cell carcinomas" J.Nat.Cancer Inst.83. 1668-1672 (1991)
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[Publications] Hirano,T.: "Interleukin 6 (IL-6) and its receptor:Their role in plasma cell neoplasias" Int.J.Cell Cloning. 9. 166-184 (1991)
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[Publications] Oritani,K.et al.: "Retinoic acids inhibits IL-6-induced macrophage differentiation and apoptosis in a murine hematopoietic cell line,Y6" manuscript in preparation.
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[Publications] Nakajima,K.et al.: "Involvement of ETS and CREB/ATF families in the IL-6 signal transduction pathway resulting in the junB gene activation" manuscript in preparation.
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[Publications] Lee,M.Y.et al.: "Bone modulation in sustained hemopoietic stimulation in mice" Blood. 70. 2135-2141 (1991)
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[Publications] Kinashi,T.et al.: "Premature expression of the macrophage colony-stimulating factor receptor on a multipotential stem cell line does not alter differentiation lineages controlled by stromal cells used for coculture" J.Exp.Med.173. 1267-1279 (1991)
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[Publications] Fukunaga,R.et al.: "Functional domains of the granulocyte colony-stimulating factor receptor" EMBO J.10. 2855-2865 (1991)
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[Publications] Asano,M.et al.: "Three individual regulatory elements of the promoter positively activates the transcription of the gene for granulocyte colony-stimulating factor" Gene. 107. 241-246 (1991)
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[Publications] Shimano,H.et al.: "Plasma cholesterol-lowering activity of monocyte colony-stimulating factor (M-CSF)" Ann NY Acad Sci. 587. 362-370 (1990)
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[Publications] Masaoka,T.et al.: "Double-blind test of human urinary macrophage colony-stimulating factor for allogeneic and syngeneic bone marrow transplantation" Br J.Haematol.76. 501-505 (1990)
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[Publications] Suzu,S.et al.: "Characterization of macrophage colony-stimulating factor in body fluids by immunoblot analysis" Blood. 77. 2160-2165 (1991)
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[Publications] Saito,S.et al.: "Enhancing effects of human macrophage colony-stimulating factor on the secretion of human chorionic gonadotropin by human chorionic villous cells and tPA30-1 cells" Biochem.Biophys.Res.Commun.178. 1099-1104 (1991)
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[Publications] Kayashima,S.et al.: "Effects of macrophage colony-stimulating factor on reduction of viable bacteria and survival of mice during Listeria monocytogenesis infection:Charactristics of monocyte subpopulations" Infection and Immunity. 59. 4677-4680 (1991)
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[Publications] Ohsaka,A.et al.: "Enhanced neutrophil functions in a patient with colony stimulating factor-producing lung cancer" J.Int.Med.230. 459-462 (1991)
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[Publications] Konenaga,M.et al.: "The role of interleukin-5 (IL-5) in protective immunity to Strongyloides venezuelensis infection in mice" Immunology. 72. 502-507 (1991)
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[Publications] Yamaguchi,N.et al.: "Murine interleukin 5 receptor isolated by immunoaffinity chromatography:comparison of determined N-terminal sequence and deduced primary sequence from cDNA and implication of a role of the intracytoplasmic domain" Int.Immunol.3. 889-898 (1991)
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[Publications] Murata,Y.et al.: "Molecular cloning and characterization of the human interleukin 5 receptor" J.Exp.Med.
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[Publications] Sonoda,E.et al.: "Differential regulation of IgA production by TGFB and IL-5:TGFB induces class switch of surface IgA B cells,whereas IL-5 promotes postswitch maturation into IgA-secreting cells" Cell.Immunol.
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[Publications] Migita,M.et al.: "Characterization of the human interleukin 5(IL-5) receptors on eosinophils" Cell.Immunol.133. 484-497 (1991)
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[Publications] Hitoshi,Y.et al.: "In vivo administration of antibody to murine IL-5 receptor inhibits eosinophilia of IL-5 transgenic mice" Int.Immunol.3. 135-139 (1991)
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[Publications] Tominaga,A.et al.: "Transgenic mice expressing a B cell growth and differntiation factor (interleukin 5) gene develop eosinophilia and autoantibody production" J.Exp.Med.173. 429-438 (1991)
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[Publications] Mita,S.et al.: "Molecular characterization of the B chain of the murine interleukin 5 (IL-5) receptor" Int.Immunol.3. 665-672 (1991)
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[Publications] Takaki,S.et al.: "Identification of the second subunit of the murine interleukin 5 receptor:Interleukin-3 receptor-like protein,AIC2B is the component of the high affinity interleukin-5 recptor" EMBO J.10. 2833-2838 (1991)
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[Publications] Takatsu,K.: "Interleukin 5 and its receptor" Microbiol.Immunol.35. 593-606 (1991)
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[Publications] Takamizawa,A.et al.: "Structure and organization of the hepatitis C virus genome isolated from human carriers" J.Virology. 65. 1105-1113 (1991)
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[Publications] Nagata,A.et al.: "An additional homolog of the fission yeast cdc25+ gene exists in human and is over-expressed in some cancer cells" New Biologist. 3. 959-968 (1991)
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[Publications] Igarashi,M.et al.: "Weel+-like gene in human cells" Nature. 353. 80-83 (1991)
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[Publications] Eiden,M.V.et al.: "Suppression of the chemically transformed phenotype of BHK cells by a human cDNA" Mol.Cell.Biol.11. 5321-5329 (1991)
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[Publications] Okazaki,N.et al.: "The ste4+ gene,essential for sexual differentiation of Schizsaccharomyces pombe,encodes a protein with a leucine zipper motif" Nucleic Acids Res.19. 7043-7047 (1991)
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[Publications] Masuda,A.et al.: "Signal transduction cascade shared by epidermal growth factor and platelet-derived growth factor is major pathway for oncogenic transformation in NRK cells" New Biologist.
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[Publications] Hatake,K.et.al.: "Human Cytokines" Blackwell Scientific Publications Inc.(Aggarwal,B.B.and Gutterman,J.U.,eds), 135-142(8) (1991)
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[Publications] Miyatake,S.et.al.: "Molecular Biology of Lymphokines" VCH Publishers,Inc., 35-37(3) (1991)
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[Publications] Yokota,T.et.al.: "Cytokines and Infectious Disease" Marcel Decker Inc.(Bermudes,L.Z.and Steems,P.,eds), (1992)
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[Publications] Motoyoshi,K.: "Frontiers of Mucosal Immunology" Elsevier Science Publishers, 903 (1991)
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[Publications] Hanazono,Y.et al.: "Myelodysplastic syndrome and cytokines" Elsevier Science Publishers B.V., 3-12(10) (1991)
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[Publications] Hirano,T.,and Kishimoto,T.(Talal,N.ed): "Autoimmunity:Molecular,Virology,Genetics,Immunologic and Clinical Aspects" Academic Press, 17 (1991)
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[Publications] Hirano,T.: "The Cytokine Handbook" Academic Press(Thompson,A.ed), 22 (1991)
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[Publications] Motoyoshi,K.: "Hematopoietic Growth Factors in Clinical Applications" Marcel Dekker Inc., 469 (1991)