1992 Fiscal Year Annual Research Report

感覚受容系の機能分化に関する比較研究

Research Project

Project/Area Number	03304010
Research Institution	Fukuoka University
Principal Investigator	冨永佳也福岡大学, 理学部, 教授 (70078591)
Co-Investigator(Kenkyū-buntansha)	三村珪一長崎大学, 教養部, 教授 (20039754) 宗岡洋二郎広島大学, 総合科学部, 教授 (40031330) 山口恒夫岡山大学, 理学部, 教授 (60000816) 渋谷達明筑波大学, 生物科学系, 教授 (00015512) 久田光彦北大学, 理学部, 教授 (70000768)
Keywords	感覚受容の生理学 / 受容器の動的構造 / 感覚情報の統合処理 / 異種感覚間の相互作用 / 昆虫・甲殻類の脳 / 神経伝達物質 / 情報伝達系の可塑化 / 神経系の発生学
Research Abstract	昨年度(平成3年度)に引き続き、主に4つの問題点から研究を進めており、各領域で次のような成果を得た。 1.受容器の動的構造複眼視細胞の光受容膜の再生が細胞内膜系のSRCを経由し、その調節にホスファチジルイノシトール輸送蛋白質と相同な膜蛋白が関与することを、ショウジョウバエの視覚突然変異体で証明した。2.高次情報伝達の素過程鱗翅目昆虫の視覚系で、菫色受容器の複眼内の配置を同定し、連絡相手が視葉板ニューロンであることを確かめた。一方、その嗅覚系では、フェロモン受容による性行動を発現駆動する前大脳ニューロンに3群があることを確認し、それらの活動と行動の関連性を明らかにした。また、甲殻類で尾扇肢の自己受容器ニューロンの応答特性と中枢投射回路を確かめた。3.感覚情報伝達路の可塑化数10種類の生理活性ペプチドを同定しており、そのうちミツバチ、ユムシ、ドブガイで発見した種類は感覚情報伝達系への関与が見込まれる。双翅目昆虫では羽化直後の臨界期の視覚経験が成虫の視覚機能の形成を決めるが、臨界期に視髄で神経伝達物質などの量的変動が起こることを明らかにした。また、鱗翅目昆虫では、幼虫単眼の視細胞が連絡するニューロンが蛹化後も退化せず、成虫の視髄に組み込まれて、複眼の中枢系介在ニューロンとして働くことを発見した。4.異種感覚間の相互作用甲殻類の脳内のノンスパイキング・巨大ニューロンが、視覚情報や重力感覚情報のみならず、歩行脚の自己受容器からの情報をも統合し、体平衡系への運動出力を形成することを確認した。5.班会議とシンポジウム今年度の研究成果を検討する班会議を開き、別に『神経回路の発生・編成・再生』および『無脊椎動物の感覚受容系と中枢』の標題で公開シンポジウムを2度にわたり開催したが、本研究を推進する上で著しい効果があった。

Research Products
(15 results)

All Other

All Publications (15 results)

[Publications] Bandai,K.Arikawa,K.and Eguchi,E.: "Localization of spectral receptors in the ommatidium of butterfly compound eye determined by polarization sensitivity." J.Comparative Physiology(A). 171. 289-297 (1992)
[Publications] Yasuyama,K.,T.Kimura.,T.Yamaguchi.: "Proctolin-like immunoreactirity in the dorsal unpaired median neurous innerrating the accessory gland of male cricket(Gryllus bimaculatus)" Zool.Sci.9. 53-64 (1992)
[Publications] Yasuyama,K.,B.Chen,T.Yamaguchi.: "Immunocytochemical evidence for the involvement of RFamide-like peptide in the neural control of cricket accessory gland" Zool.Sci.10. 39-42 (1993)
[Publications] Y.Fujisawa,T.Ikeda,K.Nomoto,Y.Y-Kamatani,H.Minakata,P.M.T.Kenny,I.Kubota and Y.Muneoka: "The FNRFamide-related decapeptide of Mytilus contains a D-amino acid residue." Comp.Biochem.Physiol.102C. 91-95 (1992)
[Publications] Y.Muneoka and M.Kobayashi: "Comparative aspects of structure and action of molluscan neuropeptides" Experientia. 48. 448-456 (1992)
[Publications] Ichikawa,T.: "Control of impulse discharge of visual interneurous by the receptive field surround in butterfly larva." Journal Experimental Biology. 171. 247-259 (1992)
[Publications] Ichikawa,T.: "Growth of axon collaterals of eclosion horomone neurons into a new release site during metamorphosis of Bombyx mori." Neuroscience Letters. 138. 14-18 (1992)
[Publications] Mimura,K.: "Effect of the visual environment on proteins and peptides in the developting brain of the fly,Boettcherisca peregrina" J.Insect Physiol.(1993)
[Publications] Sato M.: "Distribution of synapses on two types of ascending interneurons in the crayfish,Procambarus clarkii(Girard)" Cell Tissue Research. 271. 9-21 (1993)
[Publications] Nagayama T.: "A sensory map based on velocity threshold of sensory neurones from a chordotonal organ in the tailfan of the crayfish" The Journal of Comparative Physiology A. (1993)
[Publications] Kanzaki,R.,N,Sugi.& T.Sibuya.: "Self-generated zig-zag turning of Bombyx mori males during pheromone mediated upwind walking." Zool.Sci.9. 515-527 (1992)
[Publications] Kanzaki,R.& T.Shibuya.: "Long-lasting excitatin of protocerebral bilateral neurins in the pheromone-processing pathways in the male moth,Bombyx mori." Brain Res.587. 211-215 (1992)
[Publications] E.Suzuki.: "Immunocytochemical studies on light induced changes in phosphatidylinositol 4,5-bisphosphate immunoreactivity in the visual system of normal and norpA mutant of Drosophila." Neuroscience Research. 13. 155-160 (1992)
[Publications] Shimazaki,Y and Eguchi,E.: "Synthesis of 3-hydroxyretinal in the cytosol of the butterfly compound eyes." Vision Research. 33. 155-163 (1993)
[Publications] 下澤楯夫: "生物と機械" 共立出版(株), 166 (1992)

1992 Fiscal Year Annual Research Report

感覚受容系の機能分化に関する比較研究

Principal Investigator

冨永 佳也 福岡大学, 理学部, 教授 (70078591)

Research Products

[Publications] Bandai,K.Arikawa,K.and Eguchi,E.: "Localization of spectral receptors in the ommatidium of butterfly compound eye determined by polarization sensitivity." J.Comparative Physiology(A). 171. 289-297 (1992)

[Publications] Yasuyama,K.,T.Kimura.,T.Yamaguchi.: "Proctolin-like immunoreactirity in the dorsal unpaired median neurous innerrating the accessory gland of male cricket(Gryllus bimaculatus)" Zool.Sci.9. 53-64 (1992)

[Publications] Yasuyama,K.,B.Chen,T.Yamaguchi.: "Immunocytochemical evidence for the involvement of RFamide-like peptide in the neural control of cricket accessory gland" Zool.Sci.10. 39-42 (1993)

[Publications] Y.Fujisawa,T.Ikeda,K.Nomoto,Y.Y-Kamatani,H.Minakata,P.M.T.Kenny,I.Kubota and Y.Muneoka: "The FNRFamide-related decapeptide of Mytilus contains a D-amino acid residue." Comp.Biochem.Physiol.102C. 91-95 (1992)

[Publications] Y.Muneoka and M.Kobayashi: "Comparative aspects of structure and action of molluscan neuropeptides" Experientia. 48. 448-456 (1992)

[Publications] Ichikawa,T.: "Control of impulse discharge of visual interneurous by the receptive field surround in butterfly larva." Journal Experimental Biology. 171. 247-259 (1992)

[Publications] Ichikawa,T.: "Growth of axon collaterals of eclosion horomone neurons into a new release site during metamorphosis of Bombyx mori." Neuroscience Letters. 138. 14-18 (1992)

[Publications] Mimura,K.: "Effect of the visual environment on proteins and peptides in the developting brain of the fly,Boettcherisca peregrina" J.Insect Physiol.(1993)

[Publications] Sato M.: "Distribution of synapses on two types of ascending interneurons in the crayfish,Procambarus clarkii(Girard)" Cell Tissue Research. 271. 9-21 (1993)

[Publications] Nagayama T.: "A sensory map based on velocity threshold of sensory neurones from a chordotonal organ in the tailfan of the crayfish" The Journal of Comparative Physiology A. (1993)

[Publications] Kanzaki,R.,N,Sugi.& T.Sibuya.: "Self-generated zig-zag turning of Bombyx mori males during pheromone mediated upwind walking." Zool.Sci.9. 515-527 (1992)

[Publications] Kanzaki,R.& T.Shibuya.: "Long-lasting excitatin of protocerebral bilateral neurins in the pheromone-processing pathways in the male moth,Bombyx mori." Brain Res.587. 211-215 (1992)

[Publications] E.Suzuki.: "Immunocytochemical studies on light induced changes in phosphatidylinositol 4,5-bisphosphate immunoreactivity in the visual system of normal and norpA mutant of Drosophila." Neuroscience Research. 13. 155-160 (1992)

[Publications] Shimazaki,Y and Eguchi,E.: "Synthesis of 3-hydroxyretinal in the cytosol of the butterfly compound eyes." Vision Research. 33. 155-163 (1993)

[Publications] 下澤 楯夫: "生物と機械" 共立出版(株), 166 (1992)

冨永佳也福岡大学, 理学部, 教授 (70078591)

[Publications] 下澤楯夫: "生物と機械" 共立出版(株), 166 (1992)