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1992 Fiscal Year Final Research Report Summary

Highly Sensitive Taste Sensor using Highly-oriented Lipid Membranes

Research Project

Project/Area Number 03555085
Research Category

Grant-in-Aid for Developmental Scientific Research (B)

Allocation TypeSingle-year Grants
Research Field 計測・制御工学
Research InstitutionKYUSHU UNIVERSITY

Principal Investigator

YAMAFUJI Kaoru  Kyushu univ.,electronics,professor, 工学部, 教授 (90037721)

Co-Investigator(Kenkyū-buntansha) IKEZAKI Hidekazu  Anrits Corporation,Research Laboratory,engineer, 第3研究部, 研究員
HAYASHI Kenshi  Kagoshima univ.electronics and electrical engineering, associate professor, 工学部, 助教授 (50202263)
ARAKI Keijiro  Kyushu univ.,computer science and communication engineering, associate professor, 工学部, 助教授 (40117057)
TOKO Kiyoshi  Kyushu univ.,electronics,associate professor, 工学部, 助教授 (50136529)
SUEZAKI Yukio  Saga Medical School,physics lab.,professor, 教授 (80069484)
Project Period (FY) 1991 – 1992
KeywordsLipid Membrane / Polymer / Highly-Oriented / Electrolyte / LB Method / Electric-Potential
Research Abstract

The candidate proposed a taste sensor whose electrode is composed of membranes of the lipid-impregnated polymer as the transducer of taste. The transducer of this type can respond to electrolytic taste substances quite well. However, the responsibility to non-electrolytes, such as sucrose (sweetness) and quinine (bitterness), is slightly less than that of humans. Application to food industry requires a highly sensitive and durable transducer . In order to construct more stable membranes which are able to respond both electrolytes and non-electrolytes sensitively, we will try to make highly-oriented lipid membranes by the LB method. The candidate recently confirmed that the L B membrane had capability for more sensitive detection of both sourness (electrolyte) and sweetness (non-electrolyte) than that of humans.
The candidate will try to develop a taste sensor consisting of a multi-channel electrode with transducers composed of the highly-oriented membranes with different kinds of lipids which has functional groups existing in biological systems. The electric-potential pattern of the transducers represent the taste, as shown previously by the candidate. Therefore, theoretical analysis of the interaction between the assembly of lipid molecules and taste substances is relevant to clarify the taste-reception mechanism in biological systems. It is noted that the relation between taste substances and the taste is not simple because of nonlinear characteristics such as synergistic effect of "umami" substances and so on. To compare the theoretical analysis with the experimental result obtained by the taste sensor in the view point of the electro-chemical phenomenon will clarify the essence of the taste.

  • Research Products

    (13 results)

All Other

All Publications (13 results)

  • [Publications] 都甲 潔: "Electrical characteristics in an excitable element of lipid membrane" Biophysical Chemistry. 41. 143-156 (1991)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Y.SAIDA: "Taste sensing by analyzing chaotic dynamics in an excitable lipid membrane" Technical Digest of the 11th Sensor Symposium. 201-204 (1992)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Y.SAIDA: "Taste detection using chaos in excitable lipid membrane" Sensors and Materials. 4. 135-144 (1992)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] S.IIYAMA: "Cut off effect of n-alkanols in an excitable model membrane composed of dioleyl phosphate" Biophysical Chemistry. 45. 91-100 (1992)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] S.IIYAMA: "Electric excitation in an artificial lipid membrane" Trends in Physical Chemistry. 1. 121-132 (1992)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] A.SUGANUMA: "Application of a neural network to human tasting" Proceedings of the 16th Annual International Computer software & Applications. 277-282 (1992)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 末崎 幸生: "第9回麻酔メカニズム研究会講演集(その2)" 麻酔と蘇生. 259-263 (1992)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] K.Toko: "Electrical characteristics in an excitable element of lipid membrane" Biophysical Chemistry. 41. 143-156 (1991)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Y.Saida: "Taste sensing by analyzing chaotic dynamics in an excitable lipid membrane" Technical Digest of the 11th Sensor Symposium. 201-204 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Y.Saida: "Taste detection using chaos in excitable lipid membrane" Sensors and Materials. 4. 135-144 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] S.Iiyama: "Cut off effect of n-alkanols in an excitable model membrane composed of dioleyl phosphate" Biophysical Chemistry. 45. 91-100 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] S.Iiyama: "Electric excitation in an artificial lipid membrane" Trends in Physical Chemistry. 1. 121-132 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] A.Suganuma: "Application of a neural network to human tasting" Proceedings of the 16th Annual International Computer software & Applications. 277-282 (1992)

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 1994-03-24  

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