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1993 Fiscal Year Final Research Report Summary

Developmental research of a new 1020-site optical recording system for monitoring neural activity of central nervous system.

Research Project

Project/Area Number 03557006
Research Category

Grant-in-Aid for Developmental Scientific Research (B)

Allocation TypeSingle-year Grants
Research Field Neurophysiology and muscle physiology
Research InstitutionTokyo Medical and Dental University

Principal Investigator

KAMINO Kohtaro  Tokyo Medical and Dental University, School of Medicine, Professor, 医学部, 教授 (40025630)

Co-Investigator(Kenkyū-buntansha) SATO Yoko  Tokyo Medical adn Dental University, School of Medicine, Instructor, 医学部, 助手 (70251501)
SAKAI Tetsuro  Tokyo Medical and Dental University, School of Medicine, Lecturer, 医学部, 講師 (40153845)
HIROTA Akihiko  Tokyo Medical and Dental University, School of Medicine, Assistant Professor, 医学部, 助教授 (50156717)
Project Period (FY) 1991 – 1993
Keywordscentral nervous system / neural activity / optical recording / 1020-site optical recording system
Research Abstract

We have constructed a new 1020-site optical system for simultaneous recording of transmenbrane electrical activity, using a 34 x 34-element photodiode array. This new apparatus permits analysis of the spatio-temporal patterning of neural activity, such as action potentials and postsynaptic potentials, in the central nervous system, at higher spatial and temposal resolutions.

  • Research Products

    (22 results)

All Other

All Publications (22 results)

  • [Publications] Kamino,K.: "Optical approaches to ontogeny of electrical activity and related functional organization during early heart development." Physiological Reviews. 70. 53-91 (1991)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Sakai,T.: "Optical determination of impulse conduction velocity during development of the embryonic chick cervical vagus nerve bundle." Journal of Physiology(London). 439. 361-381 (1991)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Komuro,H.: "Optical detection of postsynaptic potentials evoked by vagal stimulation in the early embryonic chick brain stem slice." Journal of Physiology(London). 442. 691-649 (1991)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Momose-Sato,Y.: "Optical mapping of the early development of the response pattern to vagal stimulation in embryonic chick brain stem." Journal of Physiology(London). 442. 649-669 (1991)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Sato,K.: "Optical monitoring of early appearance of spontaneous membrane potential changes in the embryonic chick medulla oblongata using a voltage-sensitive dye." Neuroscience. 52. 55-62 (1993)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Sato,K.: "Optical assessment of spatial patterning of strength-duration relationship for vagal responses in the early embryonic chick brainstem." Japanese Journal of Physiology. 43. 521-539 (1993)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Kamino,K.: "Fluorescence Spectroscopy:New Methods and Applications" Springer-Verlag,Berlin,Germany, 310 (1992)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 佐藤容子: "膜学実験シリーズ第1巻 生体膜編。" 共立出版、東京, 424 (1993)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Kamino, K.: "Optical approaches to ontogeny of electrical and related functional organization during early heart development." Physiological Reviews. 70. 53-91 (1991)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Sakai, T., Komuro, H., Katoh, T., Sasaki, H., Momose-Sato, Y.and Kamino, K.: "Optical detemination of impulse conduction velocity during development of the embryonic chick cervical vagues nerve bundle." Journal of Physiology (London). 439. 361-381 (1991)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Komuro, H., Sakai, T., Momose-Sato, Y., Hirota, A.and Kamino, K.: "Optical detection of postsynaptic potentials evoked by vagal stimulation in the early embryonic chick brain stem slice" Journal of Physiology (London). 442. 631-648 (1991)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Momose-Sato, Y., Sakai, T., Komuro, H., Hirota, A., and Kamino, K.: "Optical mapping of the early development of the response pattern to vagal stimulation in embryonic chick brain stem." Journal of Physiology (London). 442. 649-668 (1991)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Momose-Sato, Y., Komuro, H., Sakai, T., Hirota, A.and Kamino, K.: "Optical monitoring of cholinergic postsynaptic potential in the embryonic chick ciliary ganglion using a voltage-sensitive dye." Biomedical Research. 12 Supplement 2. 139-141 (1991)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Komuro, H., Momose-Sato, Y., Sakai, T., Hirota, A.and Kamino, K.: "Optical monitoring of early appearance of spotaneous membrane potential changes in the embryonic chick medulla oblomgata using a voltage-sensitive dye." Neuroscience. 52. 55-62 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Sato, K., Momose-Sato, Y., Sakai, T., Hirota, A.and Kamino, K.: "Optical assessment of spatial patterning of strength-duration relationship for vagal responses in the early embryonic chick brainstem." Japanese Journal of Psysiology. 43. 521-538 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Kamino, K., Sakai, T., Momose-Sato, Y., Hirota, A.and Sato, K.: "Optical indications of early appearace of postsynaptic potentials in the embryonic chick brain stem." Japanese Journal of Psysiology. 43, Suppl. 1. S43-S51 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Momose-Sato, Y., Sakai, T., Hirota, A., Sato, K.and Kamino, K.: "Optical monitoring of glutaminergic excitatory postsynaptic potentials from the early developing embryonic chick brain stem slice." Annuals of the New York Academy of Sciences. 707. 454-457 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Momose-Sato, Y., Sakai, T., Hirota, A., Sato, K.and Kamino, K.: "Optical mapping of early embryonic expression of Mg^<2+>/APV-sensitive components of vagal glutaminergic EPSPs in the chick brainstem." Journal of Neuroscience. In press.

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Sato, K., Momose-Sato, Y., Sakai, T., Hirota, A.and Kamino, K.: "Optical multiple-site/sectioning recording assessment of neural response areas to glosspharyngel stimulus in the early embryonic chick brainstem." Journal of Neuroscience. in press.

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Hirota, A., Sato, K., Momose-Sato, Y., Sakai, T., and Kamino, K.: "A new simultaneous 1020-site optical recording system for monitoring neural activity using voltage-sensitive dyes." Journal of Neuroscience Methods. in press.

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Momose-Sato, Y., Sato, K., Sakai, T., Hirota, A., Matsutani, K.and Kamino, K.: "Evaluative examination of optimal voltage-sensitive dyes for optical monitoring embryonic neural activity." Journal of Neuroscience Methods. in press.

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Kamino, K., Sakai, T., Momose-Sato, Y., Komuro, H., Hirota, A.and Sato K.: Optical monitoring of postsynaptic potential in the early embryonic avian brain stem using a voltage-sensitive dye. In : Fluorescence Spectroscopy : New Methods and Applications. Ed : O.S Wolfbeis. Springer-Verlag, Berlin, Germany, pp 289-301 (1992)

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 1995-03-27  

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