• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to project page

1993 Fiscal Year Final Research Report Summary

Measurement of ERG, VEP after paired pattern reversal stimulation for detection of visual conduction disorders.

Research Project

Project/Area Number 03670429
Research Category

Grant-in-Aid for General Scientific Research (C)

Allocation TypeSingle-year Grants
Research Field Neurology
Research InstitutionYokohama City University (1993-1994)
Okinaka Memorial Institute for Medical Research (1991-1992)

Principal Investigator

KUROIWA Yoshiyuki  YOKOHAMA CITY UNIV.SCHOOL OF MED., FACULTY OF MED., PROFESSOR, 医学部, 教授 (40135249)

Co-Investigator(Kenkyū-buntansha) IDA Masayoshi  OKINAKA MEMORIAL RESEARCH INSTITUTE, STAFF, 研究員
KOJIMA Susumu  OKINAKA MEMORIAL RESEARCH INSTITUTE, STAFF, 研究員 (10183336)
ISHIYAMA Yoji  OKINAKA MEMORIAL RESEARCH INSTITUTE, STAFF, 研究員 (80151413)
Project Period (FY) 1991 – 1993
KeywordsVisual Evoked Potential / Electroretionogram / Paired Stimulation / Latency / Amplitude
Research Abstract

Visual conduction disorders consist of (1) conduction block, (2) conduction delay, and (3) fatiguability. This study was performed to produce a new laboratory test for detecting slight or subclinical abnormality of visual conduction process. For these three years, we established a new method of "paired pattern reversal stimulation." Subjects consisted of 70 healthy adults. Interstimulus intervals (ISI) were 40, 60, 80, 100, 120, 140, 160, and 180 msec. Waveform X was defined as the response after subtracting the response B (single stimulation) from the response A (paired stimulation). Both latency and amplitude were compared between the response B and X.Both ERG and VEP were recorded in this study. ERG was recorded from the gold foil electrode in the eyelid, and VEP was recorded from the mid-occipital scalp electrode. The results are following ;
1. ERG latency (1) a(p)latency, B<X, (2) b(p)latency, B<X, (3) c(p)latency, B<X
2. ERG amplitude (1) b(p)amplitude, B<X, (2) c(p)amplitude, B>X
3. VEP latency (1) P50 latency, B<X, (2) N75 latency, B<X, (3) P100 latency, B<X (4) N145 latency, B<X
4. VEP amplitude (1) N75 amplitude, B<X (2) P100 amplitude, B>X (3) N145 amplitude, B>X
The difference of latency or amplitude was the most largest between B and X, at the ISI of 40-80 msec.
This particular method was applied to two MS patients. The results showed delayd VEP latency in both B and X.

  • Research Products

    (13 results)

All Other

All Publications (13 results)

  • [Publications] 黒岩義之: "VEP(特に各波の発生起源について)" 日本脳波・筋電図技術講習会・誌. 105-123 (1991)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 黒岩義之: "視覚誘発電位" 脳波と筋電図. 19. 107-108 (1991)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 黒岩義之: "画像診断の限界と神経生理学との接点" 共済医報. 41. 198-204 (1992)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 黒岩義之: "脳疾患の画像診断と生理学的検査の接点" 日本医事新報. 3608. 13-21 (1993)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 黒岩義之: "視覚誘発電位(VEP)" Medical Practice. 8. 260-269 (1991)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 黒岩義之: "網膜電図とVEP" 臨床脳波. 33. 734-742 (1991)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 黒岩義之: "視覚誘発電位,基礎から応用まで" 下地恒毅,西村書店, 88-119 (1992)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 黒岩義之: "臨床電気生理診断セミナー" 木村淳,日本神経学会, 64-72 (1992)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Kuroiwa, Yoshiyuki: "Visual evoked potential." EEG and EMG. 19. 107-108 (1991)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Kuroiwa, Yoshiyuki: "Limitation of imaging diagnosis and its relation to neurophysiological assessment." Kyosai Ihou. 41. 198-204 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Kuroiwa, Yoshiyuki: "Imaging diagnosis of brain disorders and neurophysiological assessment." Nihon-Ijishimpo. 3608. 13-21 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Kuroiwa, Yoshiyuki: "Visual evoked potentials (VEP)." Medical Practice. 8. 260-269 (1991)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Kuroiwa, Yoshiyuki: "Electroretionograms and visual evoked potentials." Clinical EEG. 33. 734-742 (1991)

    • Description
      「研究成果報告書概要(欧文)」より

URL: 

Published: 1995-03-27  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi