1992 Fiscal Year Final Research Report Summary
Xenograft in Large Animals
| Project/Area Number |
03670579
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| Research Category |
Grant-in-Aid for General Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Research Field |
General surgery
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| Research Institution | The University of Tokyo |
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Principal Investigator |
NAGAO Takeshi Univ. of Tokyo, Inst. of Med. Sci., Associate Prof., 医科学研究所, 助教授 (90143487)
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| Co-Investigator(Kenkyū-buntansha) |
WATANABE Kenshi Univ. of Tokyo, Inst. of Med. Sci., Assistant Surgeon, 医科学研究所, 教務職員 (90201178)
TOMIKAWA Shinji Univ. of Tokyo, Inst. of Med. Sci., Associate Surgeon, 医科学研究所, 助手 (40164016)
MITA Kunji Univ. of Tokyo, Inst. of Med. Sci., Associate Surgeon, 医科学研究所, 助手 (30190672)
INOUE Sumio Univ. of Tokyo, Inst. of Med. Sci., Associate Surgeon, 医科学研究所, 助手 (80147090)
SUGIMOTO Hisayuki Univ. of Tokyo, Inst. of Med. Sci., Lecturer, 医科学研究所, 講師 (20107428)
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| Project Period (FY) |
1991 – 1992
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| Keywords | XENOGRAFT / LIVER TRANSPLANTATION / PC-1 / 血漿交換 |
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| Research Abstract |
Xenograft is one of the ideal therapeutic procedures for organ failure. We have tried xenotransplantation of the liver in large animals. The existence of natural antibody is a serious barrier in xenograft. We have carried out absorption of natural antibody with new absorbent, PC-1, that we developed. And we have also performed plasma-exchange for the removal of natural antibody. However, we have not got good results yet.
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