| Co-Investigator(Kenkyū-buntansha) |
ピッケルマイヤー ルドル ハノーファー医科大学, 教授
YAMABE Hirohiko Kyoto Univ., Faculty of Medicine, Assistant Professor, 助教授 (00135592)
TANAKA Akira Kyoto Univ., Faculty of Medicine, Assistant, 医学部, 助手 (00240820)
MORIMOTO Taisuke Kyoto Univ., Faculty of Medicine, Assistant, 医学部, 助手 (60135910)
HONDA Kazuo Kyoto Univ., Faculty of Medicine, Assistant, 医学部, 助手 (00209321)
SHIMAHARA Yasuyuki Kyoto Univ., Faculty of Medicine, Assistant Professor, 医学部, 助手 (30196498)
MORI Keiichiro Kyoto Univ., Faculty of Medicine, Assistant Professor, 医学部, 講師 (80159186)
INAMOTO Takashi Kyoto Univ., Faculty of Medicine, Assistant Professor, 医学部, 講師 (10135577)
TANAKA Koichi Kyoto Univ., Faculty of Medicine, Associate Professor, 医学部, 助教授 (20115877)
RUDOY Pichlmayr Hanover School of Veterinary Medicine, Professor
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| Research Abstract |
Perioperative management in clinical liver transplantation
Histological changes comparing with energy metabolic changes in the rejection state after liver transplantation have not ever studied. In this plan, we have tried the MTT assay of lymphocyte comparing with the changes in arterial ketone body ratio (AKBR) which reflects the energy state of the liver mitochondria after liver transplantation in Hannover Medical Center. The activity of MTT decreased not only in the rejection state but also in the infectious state after liver transplantation. Therefore, MTT assay can not be good indicator of the rejection. However, in the patient with critically decreased in AKBR the MTT activity also decreased.
As the collaboration study we have been evaluating measuring the saturation ratio of hemoglobin through the liver graft just after reperfusion using the MCPD method.
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