1994 Fiscal Year Final Research Report Summary
DIAGNOSIS OF METAL ALLERGY BYCOLORIMETRIC ANALYSIS OF PATCH TEST
| Project/Area Number |
04557084
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| Research Category |
Grant-in-Aid for Developmental Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
補綴理工系歯学
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| Research Institution | TOKYO MEDICAL AND DENTAL UNIVERSITY |
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Principal Investigator |
INOUE Masayuki TOKYO MED.&DENT.UNIV.NIASSOCIATE PROFESSOR, 歯学部, 助教授 (10013872)
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| Co-Investigator(Kenkyū-buntansha) |
MURATA Yukio MURATA COLOR RESEACH RESEARCHER, 所長
NAGAI Shigemi IWATE MED.UNIV.LECTURER, 歯学部, 講師 (20184476)
FURUKAWA Yoshitoshi IWATE MED.UNIV.LECTURER, 歯学部, 講師 (40156956)
ISHIBASHI Kanji IWATE MED.UNIV.PROFESSOR, 歯学部, 教授 (90018771)
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| Project Period (FY) |
1992 – 1994
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| Keywords | METAL ALLERGY / DIAGNOSIS / PATCH TEST / SKIN COLOR / COLORIMETRIC ANALYSIS |
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| Research Abstract |
Patch tests have been used to determine the existence of metal allergy, and its severity was ascertained by the change in skin color. However, it was quite difficult to accurately assess the change in skin color at times. Therefore, a new colorimetric diagnostic system capable of objectively evaluating color was developed to overcome this problem. This was made possible with the aid of a computer and spectrophotometer capable of making longitudinal colorimetric studies and analysis. When this new diagnostic approach compared to the conventional subjective one, the following characteristics were obtained for positive testing ones :
1.Spectral reflectance curve was of the absorption type.
2.Depth of shade(Laberheta)increased.
3.A high color difference(dE)value was observed.
4.According to the Munsell system, the hue moved toward YR.
5.Lightness decreased and there was no change in chromaticity.
According to the CIELAB color system, there was a decrease in L^*, an increase in a^*, and a decrease in b^*.
In conclusion, characteristics of this new objective approach showed significant differences in dE,spectral reflectance curve, Laberheta, and L^*, a^*, b^*, and lightness when comparing the negative and positive groups.
We developed the diagnostic system(diagnostic formula)of the change in skin color utilized multivariate analysis on the basis of the results.
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