1993 Fiscal Year Final Research Report Summary
Development of self-mixing type laser Doppler frowmetry
| Project/Area Number |
04557117
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| Research Category |
Grant-in-Aid for Developmental Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
医学一般
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| Research Institution | Kawasaki College of Allied Health |
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Principal Investigator |
MITO Keiichiro Kawasaki College of Allied Health Professions, Associate Professor, 医用電子技術科, 助教授 (40078027)
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| Co-Investigator(Kenkyū-buntansha) |
SHINOHARA Shigenobu Shizuoka University, The faculty of Engineering, Professor, 工学部・電子工学科, 教授 (80022234)
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| Project Period (FY) |
1992 – 1993
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| Keywords | Self-mixing effect / Doppler signal / Semiconductor laser diode / Near infra-red / Tissue blood flow / Multiple scattering / Photoimmunotherapy / Cancer treatment |
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| Research Abstract |
We investigated the characteristics of a self-mixed Doppler signal obtained from multiple moving targets with different velocity components theoretically and experimentally for the measurement of blood flow in tissue. The results showed that the self-mixed Doppler signal was linearly superimposed from each waveform of the different frequency components obtained from the multiple moving targets. The maximum frequency (Fmax) of the superimposed spectrum was estimated to be about 70% of the peak flow velocity of the multiple moving targets with different velocities. This value provides tentative criteria for judgment of tissue blood flow. Excellent linear relationships were obtained between the frequency (Fmax) of the blood velocity and the known blood flow velocity in the flow channel (0.994).
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