1993 Fiscal Year Annual Research Report
重症感染に起因する多臓器不全に対する肝補助装置の開発〜細網内皮系機能補助の付加による肝補助効果の増強
Project/Area Number |
04670772
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Research Institution | YAMANASHI MEDICAL UNIVERSITY |
Principal Investigator |
山本 正之 山梨医科大学, 医学部, 講師 (30158307)
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Co-Investigator(Kenkyū-buntansha) |
井上 慎吾 山梨医科大学, 医学部, 助手 (30221089)
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Keywords | 重症感染 / 肝補助 / 細胞内皮系細胞 / ガトリニウム クロライト / PGI_2 / 肝阻血 / 大量肝切除 |
Research Abstract |
主実績についてJ.Leukocyte Biologyに掲載予定論文にある。(原稿コピー集録)。現在進行中のものはGdcl_3は加〓物に対する脾摘の効果、cross circulationへの影響である。 尚、当年配当金は論文作成費用の諸経費に使われた。また、肝切除症例の術后管理、術后経過の集積による当研究への補助データを著積した。
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[Publications] Iimuro Y,Yamamoto M,Kohno H,Itakura J et al: "Blockade of liver macrophages by Gadolinium Chloride reduces lethality in endotoxemic rats" Leucocyte Biology. (印刷中). (1994)
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[Publications] Yamamoto M,Iizuka H,Matsudo M,et al: "The indications for tumor mass reduction surgery and subsequent multidisciplinary treatments in Stage IV Repatocellular carcinoma" Surgery Today.Jpn J Surg. 23. 675-681 (1993)
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[Publications] Yamamoto M,Matsudo M,Iimuro Y,et al: "Intrahepatic distant metastasis and metachronous multicentric occurrence in solitary hepatocellular carcinoma of less than Five centimeteas in diameter" Surgery Today.Jpn J Surg. 23. 969-978 (1993)
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[Publications] Yamamoto M,Iizuka H,Fujii H,et al: "Hepatic arterial infusion of Interleukin-2 in advanced hepatocellular carcinoma" Acta Oucologica. 32. 43-51 (1993)
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[Publications] Yamamoto M,Mogaki M,Matsuda M,et al: "A possible prototype of multifocal recurrence after liver resection of hepatocellular carcinoma:report of a case" Surgery Today.Jpn J Surg. 23. 830-835 (1993)
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[Publications] Matsuda M,Yamamoto M,Matsumoto Y.: "An evaluation of the flow cytometric nuclear DNA analysis of intrahepatic multinodular hepatocellular carcinoma for a diagnosis of their multicentricity" Surgery Today.Jpn J Surg. 24. 13-18 (1994)
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[Publications] Nagahori K,Yamamoto M,Kohno H,et al: "“Expression of the antimetastatic gene nm23 in human heratocellular carcinoma"in Takahashi T(ed.)Recent advances in management of digestive cancers." Springer Verlag, 607-609 (1993)