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1995 Fiscal Year Final Research Report Summary

Study on Guide System Based on the Blood Flow Force for Intravascular Catheter

Research Project

Project/Area Number 05402035
Research Category

Grant-in-Aid for General Scientific Research (A)

Allocation TypeSingle-year Grants
Research Field Intelligent mechanics/Mechanical systems
Research InstitutionThe University of Tokyo

Principal Investigator

NAKAJIMA Naomasa  Graduate School of Eng., The Univ.of Tokyo, Professor, 大学院・工学系研究科, 教授 (00011073)

Co-Investigator(Kenkyū-buntansha) MURAKAMI Tamotsu  Graduate School of Eng., The Univ.of Tokyo, Associate Professor, 大学院・工学系研究科, 助教授 (20212251)
IMACHI Koh  Faculty of Medical Science, The Univ.of Tokyo, Professor, 医学部, 教授 (10010076)
FUJIMASA Iwao  Research Center for Advanced Science and Technology, The Univ.of Tokyo, Professo, 先端科学技術研究センター, 教授 (30010028)
Project Period (FY) 1993 – 1995
KeywordsCatheter / Actuator / Blood vessel / Detaching method / Laser / Micromachine
Research Abstract

It is usually difficult to guide a catheter safely inside blood vessels. We have devised a guide system based on the fluid force of blood vessel in order to control the direction of advance of a catheter being passed through artery blood vessels with 2-6 mm inner diameter. This system consists of a cylindrical streamer with a 1 mm diameter, 1.5 mm long and 20mum wall thickness, two supporting legs and one filament of 20 mum. Movement of the streamer can be controlled by adjusting the length of the wire. We studied the behavior of the cylindrical streamer by numerical analysis of fluid force, and investigated the cahracteristics of a model system by experiment using a simulator of pulsating blood flow (range of Reynolds number : 71-930, dynamic viscosity : 1-6 mm2/s). We obtained relation between attack angle and dimensionless lift, dimensionless drag and dimensionless lift, and then designed a prototype guide system and succeeded to guide branched vessels of the simulator.
A new type of actuator which consists of an eccentric thin silicon rubber tube and deforms spirally by hydraulic pressure was invented to simplify the control of a position and an angle of the streamer, and showed its usefulness in experiment.
Also a safety detaching method for endovascular treatment with laser light was invented. We attached the mechanism to the end of a catheter and confirmed its usefulness by experiments on rabbits.

  • Research Products

    (16 results)

All Other

All Publications (16 results)

  • [Publications] Nakajima,N.: "Small Wonder" Look Japan. 39-449. 22-23 (1993)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 中島尚正 村上存: "ミリマシンの設計" 精密工学会誌. 60-3. 363-366 (1994)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 中島尚正: "マイクロマシンの設計論" 日本ロボット学会誌. 12. 514-518 (1994)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 朱忠山,鎌原健志 村上存,中島尚正: "血流を利用した血管内カテーテルガイドシステムの研究" 日本機械学会論文集(C編). 61-592. 142-149 (1995)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 朱忠山、村上存 中島尚正 他: "血管内手術のためのレーザ光を用いた新しい離脱法" 薬理と臨床. 5-7. 1189-1192 (1995)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Nakajima,N.: "Micromachine as Intelligent Artfacts" The 1st International Symposium on Research into Artifacts. 48-51 (1993)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 中島尚正他: "超技術マイクロマシン" NTT出版, 255 (1993)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 中島尚正: "機械設計-基本原理からマイクロマシンまで-" 東大出版会, 221 (1993)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Naomasa Nakajima: "Small Wonder" Look Japan. 39-449. 22-23 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Naomasa Nakajima and Tamotsu Murakami: "Millimachine Design" Journal of the Japan Society for Precision Engineering. 60-3. 363-366 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Naomasa Nakajima: "Design Methodology for Micromachines" JRSJ.12, No.4. 514-518 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Zhongshan Zhu, Kensi Kanbara, Tamotsu Murakami and Naomasa Nakajima: "Study on Guide System of an Intravascular Catheter" JSME International Journal (C). 61-592. 142-149 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Zhongshan Zhu, Tamotsu Murakami, Naomasa Nakajima, et al: "A Newly Developed Detaching Method for Intravascular Surgery with Laser Light" Clinical Pharmacology and Therapy. 5-7. 1189-1192 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Naomasa Nakajima: "Micromachine as Intelligent Artifacts (invited paper)" The 1st International Symposium on Research into Artifacts. 48-51 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Naomasa Nakajima, et al: Super Technology-Micromachine-. NTT Press, (1993)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Naomasa Nakajima: Machine Design-from Basic Principle to Micromachine-. Tokyo Univ.Press, (1993)

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 1997-03-04  

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