1995 Fiscal Year Final Research Report Summary
Development of The Jet Pump for Left and Right Heart Assist.
| Project/Area Number |
05557063
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| Research Category |
Grant-in-Aid for Developmental Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Thoracic surgery
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| Research Institution | TOHOKU UNIVERSITY |
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Principal Investigator |
UCHIDA Naoki Tohoku University, School of Medicine Assistant Proffesor, 医学部附属病院, 講師 (70241635)
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| Co-Investigator(Kenkyū-buntansha) |
FUKUTOME Akira Nippon Zeon Co., Ltd., 開発研究部
MIURA Makoto Tohoku University, School of Medicine Assistant Proffesor, 医学部, 講師 (50239191)
NITTA Shin-ichi Tohoku University, Institute of Development, Aging and Cencer Associate Proffeso, 加齢医学研究所, 助教授 (90101138)
HASHIMOTO Hiroyuki Tohoku University, Institute of Fluid Science Proffesor, 流体科学研究所, 教授 (10006174)
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| Project Period (FY) |
1993 – 1995
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| Keywords | Jet Pump / Circulation Support / Right Heart Assist Device / Severe Heart Failure / Right Heart Failure / Percutaneous Insertion |
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| Research Abstract |
We have developed the micro jet pump as a heart assist device. Jet pump was consisted in order NOZZLE,INLET,THROAT and DIFFUSER.All compornents were fabricated to cone or column pipe on the same axis and there was no moving parts in this pump. We made 2 types of models in order to get the datum in 2 enviroment. One made from brass was the type for bench test to examine the caracteristics of the pump, and another made from acril resin and vinylchrolide was the type for animal experiment.
In the bench test, we got 3070 ml/min of pump output by 1010 ml/min of jet flow volume against 40 mmHg afterload using 40% glycerine solusion. We measured flow velosity by Fiberoptic Laser Velocimeter, and maximum jet flow velosity was within 10 m/sec which was reported previously as the comparativery safe zone for machanical hemokysis.
We performed animal experiments using adult goat. When natural heart was the condition of ventricular fiblilation under the assist of left heart bypass, 1.8 or 2.0 l/min of jet flow in right heart system made 2.5 l/min of increase of left heart output.
In conclusion, although there remain many probrems for clinical usage of jet pump, including heamolysis, positioning and pump efficiency, we hope it would be useful device for right heart assist. And the use of micro jet pump for left heart assist and child heart assist should be study in the future.
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