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1995 Fiscal Year Final Research Report Summary

Computer aided diagnosis system for lung cancer CT images

Research Project

Project/Area Number 05558033
Research Category

Grant-in-Aid for Developmental Scientific Research (B)

Allocation TypeSingle-year Grants
Research Field Intelligent informatics
Research InstitutionToyohashi University of Technology

Principal Investigator

YAMAMOTO Shinji  Toyohashi University of Technology, Professor, 工学部, 教授 (80230556)

Co-Investigator(Kenkyū-buntansha) HAO Jiang  Toyohashi University of Technology, Assistant Professor, 工学部, 助手 (00242917)
TAKAGI Hiroshi  Hitachi Medical Corpolation, Chief engineer, CT設計部, 主任技師
IINUMA Takeshi  Saitama Institute of Technology, Professor, 工学部, 教授 (60159572)
TATENO Yukio  National Institute of Radiological Science, 嘱託 (90163493)
MATSUMOTO Mitsuomi  Tokyo Metropolitan College of Allied Medical Sciences, Professor, 放射線科, 教授 (20209654)
Project Period (FY) 1993 – 1995
KeywordsLung cancer / Image prosessing / Pattern recognition / Computer aided diagnosis / CT image
Research Abstract

This paper reports the image processing technique for computer-aided diagnosis of lung cancer by CT (LSCT). LSCT is the newly developed mobile-type CT scanner for the mass screening of lung cancer by our project team. In this new LSCT system, one essential problem is the increase of image informantion to about 30 slices per person from 1 X-ray film. We tried to reduce the image information drastically to be displayd for the doctor, by image processing techniques, as follows.
NO.1 approach (MIP method)
MIP mehtod (maximum intensity projection)is considered, where the three-dimensional information composed of 30 slices of patient's lung tissue is displayd by a projection on the two-dimensional plane. The most important problem to apply MIP method for LSCT is to delete beforehand the interfering organ signals that could mask the pathological shadows. We developed a new and stable method for it using mathematical morphology, Split-Quoit filter, model information, and active contour model (snake).
This method is applied for 68 patient samples and the result is promissing.
NO.2 approach (Quoit filter method)
A new method is introduced which automatically recognizes the candidate regions for the pathological shadows. By displaying only the slices containing the candidates regions to the doctor, the number of cross sections to bediagnosed can be drastically reduced.
The shadow of the lung cancer which exists in the lung field, appears isolated and with a small area. By utilizing this property, 2-D , 3-D Quoit filters (Q-filters) and MIP-2D-Q filter are developed to extract the isolated shadow automatically, where Q-filters are those based on mathematical morphology.
This method is applied for 68 patient samples including 1809 images, and the number of displayd images to be diagnosed by the doctor is reduced to 144 images, which means the reductin rate 8% (2.1 images/patient). Among those, the 5 cancer patients are extracted correctly.

  • Research Products

    (12 results)

All Other

All Publications (12 results)

  • [Publications] 山本眞司: "肺癌検診用X線CT(LSCT)の基本構想と診断支援用画像処理方式の検討" 電子情報通信学会論文誌. J76-D-II. 250-260 (1993)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] S.Yamamoto: "Image Processing for Computer-Aided Diagnosis of Lung Cancer by CT(LSCT)" Systems and Computers in Japan. 25. 67-80 (1994)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 山本眞司: "画像前処理付MIP法による肺癌検診用X線CT画像の表示" Medical Image Technology(日本医用画像工学会論文誌). 12. 737-747 (1994)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 中山正人: "3次元モルフォロジカルフィルタによる肺癌病巣自動認識の検討 -肺癌検診用X線CT(LSCT)の診断支援(第3報)-" Medical Image Technology(日本医用画像工学会論文誌). 13. 155-164 (1995)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 富田稔啓: "モデル情報と最小値投影法による肺野領域抽出" JAMIT FRONTIER'96講演論文集. 17-20 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 山本眞司: "らせんCT肺がん検診システムにおける肺野領域自動抽出の高度化" 胸部CT検診(第3回胸部CT検診研究会). 3. 23-24 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] S.Yamamoto: "Image Processing for Computer-Aided Diagnosis of Lung Cancer by CT (LSCT)" The Transactions of the Institute of Electronics, Information and Communication Engineers D-II. Vol.J76-D-II. 250-260 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] S.Yamamoto: "Image Processing for Computer-Aided Diagnosis of Lung Cancer by CT (LSCT)" Systems and Computers in Japan. Vol.25. 67-80 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] S.Yamamoto: "A Modified MIP Processing Method for Reducing the Lung Cancer X-ray CT Display Images" Medical Imaging Technology. Vol.12. 737-747 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] M.Nakayama: "Study of 3D Morphological Filtering Applied for Automatic Detection of Lung Cancer X-ray CT" Medical Imaging Technology. Vol.13. 155-164 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] T.Tomita: "Lung region extraction based on the model information and the inversed MIP method" Proc.Jamit Frontier '96. 17-20 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] S.Yamamoto: "Lung region extraction based on the 3-D snake" 3rd Lung-CT-Screening Conference Lung CT Screening. Vol.3. 23-24 (1996)

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 1997-03-04  

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