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1995 Fiscal Year Final Research Report Summary

Cardiovascular systems in fetus and neonates

Research Project

Project/Area Number 05670697
Research Category

Grant-in-Aid for General Scientific Research (C)

Allocation TypeSingle-year Grants
Research Field Pediatrics
Research InstitutionKitasato University

Principal Investigator

HIRAISHI Satoshi  School of Medicine, Kitasato University Associate Prof., 医学部, 助教授 (80118835)

Co-Investigator(Kenkyū-buntansha) AGATA Youtaro  School of Medicine, Kitasato University Assistant Prof., 医学部, 講師 (80146430)
MISAWA Hitoshi  School of Medicine, Kitasato University Assistant Prof., 医学部, 講師 (30146427)
Project Period (FY) 1993 – 1995
KeywordsFetus / Neonate / Cardiac output / pulmonary artery / Pulmonary vein / Regional blood flow / t-VSD / Echocardiography
Research Abstract

Echocardiograpyh was used to investigate circular systems in fetus and neonates.
Results. 1. Left ventricular output (LVO) and regional blood flow distribution : LVO increases 2-fold over the fetal level immediately after birth in neonates. The increase of LVO was not for the enhancement of organ blood flow but for the maintaing the purfusion pressure in the face of left-toright shunting through the ductus arteriosus. 2. Effects of delibery mode on cardiovascular adaptation : There were no significant difference of the adaption between delibery mode. 3. Incidence and natural course of trbecular septal defect (t-VSD) : We showed that t-VSD was seen in 2% and spontaneous closure occurred most commonly during the first 6 monthes of life and it was observed in 76% by 1 yearof age. 4. Quantitative evaluaion of the morphology of the PA branches : Our new technique permitted the size, stenoses and atresia of the PA branches in various types of congenital heart disease. 5. Pulmonary venous flow pattern during early neonatal life : The continuous velocity waveform was seen immediately afterbirth, suggesting a sudden increase in both pulmonary circular volume inrelatively hypoplastic pulmonary vein and pulmonary hypertension.

  • Research Products

    (17 results)

All Other

All Publications (17 results)

  • [Publications] Youtaro Agata: "Changes in pulmonary verous flow pottern during early neonatal period" British Heart Journal. 71. 182-186 (1994)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Satoshi Hiraishi: "Noninvasive quantitative evaluation of the morphology of the major pulmonary artery branches in cyanotic congenital heart disease" Circulation. 89. 1306-1316 (1994)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Youtaro Agata: "Regional blood flow distribution and left ventricular output during neonatal life" Pediatric Research. 36. 805-810 (1994)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 三沢仁司: "心エコー図により胎生期に観察し得た,卵円孔閉鎖を伴った左心低形成症候群亜型の1例" 日本小児科学会雑誌. 98. 1616-1621 (1994)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Satoshi Hiraishi: "Obstriction of the proximal pulmonary branches after banding of the pulmonary trunk" American Journal of Cardiology. 76. 842-846 (1995)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Youtaro Agata: "Hemodynamic adaptations at birth and neonates delivered vaginally and by cesarean section." Biology of Neonates. (in press).

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 平石聰: "周産期の画像診断" 東京医学社, 9 (1995)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 平石聰: "year note(内科,外科等編)" メディック メディア, 11 (1995)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Hiraishi S.Agata Y et al.: "Incidence and natural course of trabecular ventricular septal defect : Two-dimentional echocardiography and color Doppler flow imaging study." J Pediatr. 120. 409-415 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Agata Y,Hiraishi S et al.: "Changes in pulmonary venous flow pattern during early neonatal life." Br Heart J. 71. 182-186 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Hiraishi S,Misawa H et al.: "Noninvasive quantitative evaluation of the morphology of the major pulmonary artery branches incyanotic congenital heart disease. Angiocardiographic and echocardiographic correlative study." Circulation. 89. 1306-1316 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Agata Y,Hiraishi S et al.: "Regional blood flow distribution and left ventricular output during early neonatal life : A quantitative ultrasonographic assessment." Pediatr Res. 36. 805-810 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Misawa H,Hiraishi S et al.: "A case of premature closure of the foramen ovale in an unusual form of hypoplastic left heart syndrome, diagnosed by fetal echocardiography." J Jap Pediatr Societ. 98. 1616-1621 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Hiraishi S,Misawa H et al.: "Obstruction of the proximal pulmonary artery branches after banding of the pulmonary trunk." Am J Cardiol. 76. 842-846 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Agata Y,Hiraishi S et al.: "Hemodynamic adaptations birth and neonates delivered vaginally and by cesarean section." Biol Neonate. (in press). (1995)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Hiraishi S.: "Early diagnosis of fetal heart disease." J Jap Perinatology. 25. 757-761 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Hiraishi S.: "Echocardiographic evaluation of the heart in fetus and neonates. -- Ventricular hypertrophy, dilatation and cardiac tumor --." J Jap Perinatology. (suppl). 435-443 (1995)

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 1997-03-04  

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