• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to project page

1995 Fiscal Year Final Research Report Summary

Development of implantable programmable skeletal muscle stimulator

Research Project

Project/Area Number 05671113
Research Category

Grant-in-Aid for General Scientific Research (C)

Allocation TypeSingle-year Grants
Research Field Thoracic surgery
Research InstitutionShinshu University

Principal Investigator

FUKAYA Yukio  Shinshu University Hospital Assistant, 医学部附属病院, 助手 (80199174)

Co-Investigator(Kenkyū-buntansha) KURODA Hideo  Shinshu University Hospital Assistant, 医学部附属病院, 助手 (60234613)
Project Period (FY) 1993 – 1995
KeywordsCardiomyoplasty / Implantable Muscle Stimulator / Circulatory Support / Rapid Pacing
Research Abstract

Clinical trials of Dynamic Cardiomyopalsy, which is a technique of circulatory support using a latissimus dorsi muscle, will be begun soon in Japan. Under the concept that sufficient animal experiments before clinical trials is indispensable, we have been carrying on developing an implantable skeletal muscle stimulator for animal experiments(MCMS-1110), which will be able to satisfy the various demands of investigators in this field. We implanted MCMS-1110 into dogs for testing long-term reliability. In the 7 trials, 3 stimulators continued to operate for 181 days, 234 days and 349 days, respectively. By the analysis of theses results, we concluded that MCMS-1110, which has the problems ; its size, battery capacity, electrodes etc. at present, will be a favorable and reliable stimulator by settling these problems.
A excellent heart failure model is indispensable for evaluation of effects of Dynamic Cardiomyoplasty, and the rapid pacing method seems to be the most favorable one. As there is no implantable stimulators having the rapid pacing mode in Japan, we started the study to develop the new implantable stimulator which has rapid pacing function by adding the function to the MCMS-1110. Succeeding the main characteristics of MCMS-1110, we make the new implantable stimulator : MCMS-1111. MCMS-1111 can stimulate a heart with maximum 350 bpm by changing the ROM of MCMS-1110, and now we are carrying on animal experiments to evaluate its potentials.

  • Research Products

    (12 results)

All Other

All Publications (12 results)

  • [Publications] 篠原正典: "Dynamic Cardiomyoplastyにおける骨格筋疲労の検出-加速度センサを用いて-." 骨格筋の心臓への応用. 7:(in press).

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 篠原正典: "急性実験用小型骨格筋刺激装置の有用性." 骨格筋の心臓への応用. 6. 9-11 (1994)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 黒田秀雄: "心臓同期プログラム可能植え込み型骨格筋刺激装置(MCMS-1110の植え込み試験成績." 骨格筋の心臓への応用. 6. 12-13 (1994)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 篠原正典: "加速度センサを用いた骨格筋疲労の検出." 骨格筋の心臓への応用. 5. 1-4 (1993)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 黒田秀雄: "バースト刺激型骨格筋刺激装置(植え込み,心臓同期およびプログラム可能型)の開発." 骨格筋の心臓への応用. 5. 26-29 (1993)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 篠原正典: "植え込み型骨格筋刺激装置の開発." 人工臓器. 22. 1224-1227 (1993)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Masanori Shinohara: "Detection of skeletal muscle fatigue in Dynamic Cardiomyoplasty-using a accelerometer-." Application of Skeletal Muscle for Cardiac Assist. 7(in Press).

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Masanori Shinohara: "Development of small-sized stimulator for skeletal muscle for acute animal experiment." Application of Skeletal Muscle for Cardiac Assist. 6. 9-11 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Hideo Kuroda: "Results of implantation test of R wave synchronous programmable implantable stimulator for skeletal muscle(MCMS-1110)." Application of Skeletal Muscle for Cardiac Assist. 6. 12-13 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Masanori Shinohara: "Detection of skeletal muscle fatigue using a Accelerometer. Application of Skeletal Muscle for Cardiac Assist" 5. 1-4 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Hideo Kuroda: "Development of burst stimulator(implantable, R wave synchronous and programmable)for skeletal muscle." Application of Skeletal Muscle for Cardiac Assist. 5. 26-29 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Masanori Shinohara: "Development of an implantable stimulator for skeletal muscle." Jpn J Artif Organs. 22. 1224-1227 (1993)

    • Description
      「研究成果報告書概要(欧文)」より

URL: 

Published: 1997-03-04  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi