1994 Fiscal Year Final Research Report Summary
Early detection of ovarian malignancy by color doppler sonography and serum manganese superoxide dismutase
| Project/Area Number |
05671345
|
|---|
| Research Category |
Grant-in-Aid for General Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Obstetrics and gynecology
|
|---|
| Research Institution | ASAHIKAWA MEDICAL COLLEGE |
|---|
Principal Investigator |
ISHIKAWA Mutsuo ASAHIKAWA MEDICAL COLLEGE DEPARTMENT OF OBSTETRICS AND GYNECOLOGY,PROFESSOR, 医学部, 教授 (20002131)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
TAMATE Kenichi ASAHIKAWA MEDICAL COLLEGE DEPARTMENT OF OBSTETRICS AND GYNECOLOGY,STAFF ASSOCIAT, 医学部, 助手 (90207233)
SENGOKU Kazuo ASAHIKAWA MEDICAL COLLEGE DEPARTMENT OF OBSTETRICS AND GYNECOLOGY,ASSOCIATE PROF, 医学部, 助教授 (30163124)
|
|---|
| Project Period (FY) |
1993 – 1994
|
| Keywords | ovarian malignacy / pulasatility index / CA 125 / Mn-SOD |
|---|
| Research Abstract |
To evaluate the efficiency of color doppler uetrasonography as the predictor of malignant ovarian tumors and to compare the results with serum manganses superoxide dismutase (Mn-SOD) levels for predicting ovarian malignancy. There were a signifocant difference in pulsatility index (PI) value of ovarian vessel between benign and malignant tumors. The specificity of morphorogic findings and CA125 was lower than that of P1 measurement, but sensitivty was not different among the three methods. In addition, serum Mn-SOD level measurements showed high diagnostic value in malignant ovarian tumor patients. PI measurements by tranvaginal color doppler ultrasound combined with Mn-SOD levels could be an accurate and appropriate screaning method for ovarian tumors.
|
