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1994 Fiscal Year Final Research Report Summary

A pilot study of new adhesion system of composite resion to dentin

Research Project

Project/Area Number 05671597
Research Category

Grant-in-Aid for General Scientific Research (C)

Allocation TypeSingle-year Grants
Research Field Conservative dentistry
Research InstitutionHIROSHIMA UNIVERSITY

Principal Investigator

SATOU Naoki  Hiroshima Univ.School of Dent.Associate Professor, 歯学部, 助教授 (20136097)

Co-Investigator(Kenkyū-buntansha) MORIKAWA Akihiro  Hiroshima Univ.Scool of Dent.Instructure, 歯学部, 助手 (40230099)
MATSUMAE Izumi  Hiroshima Univ.School of Dent.Instructure, 歯学部, 助手 (80183614)
URABE Hidenori  Hiroshima Univ.School of Dent.Lecture, 歯学部・附属病院, 講師 (10231185)
SHINTANI Hideki  Hiroshima Univ.School of Dent.Professor, 歯学部, 教授 (80034239)
Project Period (FY) 1993 – 1994
KeywordsTannic acid / Dentin collagen / Oral streptococci / Bonding agent
Research Abstract

This in vitro study examined the effect of concentration and/or incubation time of tannic acid to dentin and bacteria. The results showed that tannic acid inhibited the dissolution of dentin collagen treated with tripsin and phosphoric acid, depending on the increasing of concentration and incubation time of tannic acid. SEM study also revealed tannnic acid protected the collagen structure treated with tripsin and phosphoric acid. Minimal inhibitory concentration of tannic acid to S.mutans was 300 mug/ml, while that of another streptococci was 400mug/ml. Phenol coefficient of tannic acid to S.mutans OMZ 175 was 0.6.these results indicate that antimicrobial action of tannic acid give play to strain such as S.mutans. Strerillizing power of power of 300 mug/ml tannic acid with S.mutans OMZ 175 for 15 min incubation times was the highest among the strains which were haevested from stationally phase, survival rate of S.mutans OMZ 175 decreased to 2% of control. As the results of their being coated and/or uncoated saliva, the surface hydrophobicity of all restoratives and teeth decreased and their negative surface charge increased when these surfaces were treated with tannnic acid. The number of adherent streptococci decreased under above conditions. Antimicribial action of bonding agent including tannic acid showed higher than that of bonding agent without tannic acid. However the specimens without tannic acid which were not cured or were cred and immediately used investigation in early time also showed antimicribial action. Bonding agent including tannic acid exhibited high adaptation to enamel and dentin surfaces. As suggested these results that tannic acid improve anti-enzyme property of dentin and antimicrob ial action, the existence of tannic acid between tooth and restorative surfacies is useful for inhibitation of secondory caries.

  • Research Products

    (6 results)

All Other

All Publications (6 results)

  • [Publications] 齋藤さつき: "タンニン酸の抗う蝕作用に関する基礎的研究" 広大歯誌. 25. 72-87 (1993)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Naoki Satou: "Acidogenicity of Streptococcus mutans at different pH conditions in a chemostat" The Jounal of Hiroshima University Dental Society. 26. 101-105 (1994)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Naoki Satou: "Effect of tannic acid solution on hydroproline in dental collagen" J.Prosthet.Dent.(in press).

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Satsuki Saito: "Basic studies on anti-caries activity of tannic acid." Jounal of Hiroshima Univ.Dental Society. 25. 72-87 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Naoki Satou: "Acidogenicity of Streptococcus mutans at different pH conditions in a chemostat." Jounal of Hiroshima Univ.Dental Society. 26. 101-105 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Naoki Satou: "Effect of tannic acid solution on hydroproline in dental collagen." J.Prosthet.Dent. (in press).

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 1996-04-15  

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