1994 Fiscal Year Annual Research Report

長期宇宙滞在による生体の機能と形態への影響

Research Project

Project/Area Number	06354006
Research Institution	Nagoya University
Principal Investigator	渡邉悟名古屋大学, 環境医学研究所, 教授 (00021361)
Co-Investigator(Kenkyū-buntansha)	山下雅道宇宙科学研究所, 助教授 (60107480) 池永満生京都大学, 放射線生物研究センター, 教授 (70025378) 菅洋東北大学, 遺伝生態研究センター, 教授 (00124587) 河崎行繁三菱化学生命科学研究所, 主任研究員高橋景一国際基督大学, 教養学部, 教授 (40011481)
Keywords	宇宙環境 / 生物衛星 / 微生物 / 小動物 / 植物 / クローン寿命 / 重力感受 / 無重力順応
Research Abstract	長期宇宙環境滞在の研究手段としての生物衛星計画は、平成3年8月に本総合研究(B)の研究分担者を中心として結成し、第1回の生物衛星研究会を宇宙科学研究所において発足し、同年9月には名古屋大学において小型衛星研究会と合同で生物衛星シンポジウムを開催した。以後、生物が宇宙環境に長期間にわたり暴露されたときに生ずる生体への影響を研究し、殊に無重力と放射線の影響を対象に考えて研究の主目標として調査研究を進めて来た。本総合研究(B)の研究班ではさらに微生物、微小動物、植物の各研究分野から生物衛星への可能性と実験の提案を主体とした調査研究が行われた。宇宙環境下における微生物の成長と変動と新しい検出方法の研究について河崎が報告し、原生動物(ゾウリムシ)のクローン寿命の解析について最上が報告、ゾウリムシの重力応答の研究については高橋、村上が報告、ショウジヨウバエの突然変異発生率と宇宙放射線の関係を調べた池永の研究報告、過去の生物衛星実験として旧ソ連のコスモス衛星を用いたラットの実験についての渡邉の報告、ラットの皮膚の細胞培養の抗癌生蛋白質の挙動についてIML-2のスペースシャトル実験の結果についての大西の報告、同じくIML-2実験の金魚無重力順応の実験結果について高林、SL-J実験の鯉の無重力順応の実験結果について森がそれぞれ報告し、更に植物の擬似微小重力下における形態形成、成長、分化について山田および神坂が、生物衛星の工学的な検討について山下が、閉鎖生命維持システムの開発について大坪が報告した。以上の研究報告は長期宇宙環境滞在による生体への影響を様々な角度から捕らえた研究成果であり我が国の宇宙生物研究体勢の最先端を成すものである。

Research Products

(32 results)

All Other

All Publications (32 results)

[Publications] Watanabe S: "Paraboric flight experiments on physiological data acquisition and processing technologies using small jet aircraft (MU300)." J.of Grav.Physiol.1(1). 92-95 (1994)
[Publications] Watanabe S: "Telescience testbed experiments for biomedical studies: Fertilization potential recording of amphibian eggs using tele-manipulation under stereoscopic vision." Acta Astronautica. 33. 189-194 (1994)
[Publications] Kato T Jr: "Cloning of a marsupial DNA photolyase gene and the lack of related nucleotide sequences in placental mammals." Necleic.Acids.Res.20. 4119-4124 (1994)
[Publications] 井尻憲一: "微小重力下におけるメダカの行動" 宇宙航空環境医学. 31. 20-23 (1994)
[Publications] 井尻憲一: "メダカの宇宙における飼育と発生学実験の基礎実験" パラボリックフライト. 4(1). 21-28 (1994)
[Publications] Nitta K: "Possible Contributions to Earth Science Program and Others." Adv.Space Res.14. 125-134 (1994)
[Publications] Gunge N: "UV hypersensitivity of yeast linear plasmids." Current Genetics. 26. 369-373 (1994)
[Publications] Matsumoto H: "p53 proteins accumulated by heat stress associate with heat shock proteins HSP72/HSC73 in human glioblastoma cell lines." Cancer Lett.87. 39-46 (1994)
[Publications] Masuda Y: "Changes in the rheological properties of the cell wall of plant seedlings under simulated microgravity conditions." Biorheo.31. 171-177 (1994)
[Publications] 河崎行繁: "地球外微生物の探査." 日本宇宙生物科学学会会誌宇宙生物科学. 8. 103-112 (1994)
[Publications] 古賀一男: "宇宙空間における視覚安定性の研究" 宇宙生物科学. 7(4). 333-339 (1994)
[Publications] 古賀一男: "宇宙実験に随伴する困難な技術的問題" 光学. 23(1). 111-115 (1994)
[Publications] Abe K: "Graviresponding sites on shoots of normal and ｀lasy´ rice seedings." Physiologia plantarum. 92. 371-374 (1994)
[Publications] Mori S: "Visuo-vestibular adaptaion in fish under prolonged microgravity." Proc.of 19th Int.Symp.Space Technol.Sci.879-881 (1994)
[Publications] Mori S: "Space experiment using large-sized fish: in case of carp in Spacelab-J mission." Acta Astronautica. 33. 41-47 (1994)
[Publications] Arao T: "Biosynthesis of polyunsaturated lipids in the diatom,Paeodactylm tricornutum." Phytochem.36. 629-635 (1994)
[Publications] Hotta T: "Interrelationship between O^6-alkylguanine-DNA alkyltransferase activity and susceptibility to chloroethylnitrosoureas in several glioma cell lines." J.Neuro-Oncol.17. 1-8 (1993)
[Publications] Hoson T: "Vegetative growth of higher plants on a three-dimensional clinostat." Micrograv.Sci.Technol.6. 278-281 (1993)
[Publications] Suge H: "Effect of cytokinin and anticytokinin on the tillering of barley." Jpn.J.Crop Sci.62. 595-600 (1993)
[Publications] Mogami Y: "Beating of cilia of sea urchin embryos: a critical comparison of the normal and reversed beating of cilia of isolated cells." J.Exp.Biol.175. 251-266 (1993)
[Publications] Yamada M: "Plant growth under clinostat-microgravity condition." Biological Sci.in Space. 7(2). 116-119 (1993)
[Publications] Takabayashi A: "Posture control of fish related to gravity input." Proc.of 18th Int.Symp.Space Technol.Sci.2059-2063 (1992)
[Publications] Takabayashi A: "Effects of visual and vestibular apparates lesions on goldfish dorsal light response." Environ.Med.36. 187-190 (1992)
[Publications] Otsubo K: "Carbon Dioxide Adsorption Characteristics of Solid Amine." Proc.of 18th Int.Symp.Space Technol.Sci.1431-1438 (1992)
[Publications] Bauker R: "Gravity-controlled gliding velocity in Loxodes." Eur.J.Protistol.28. 238-245 (1992)
[Publications] Machemer H: "Short-term microgravity to isolate graviperception in cells." Micrograv.sci.technol.3. 119-123 (1992)
[Publications] Mogami Y: "Regulation of ciliary movement in sea urchin embryos: dopamine and 5-HT change the swimming behaviour." Comp.Biochem.Physiol.101C. 251-254 (1992)
[Publications] Yamashita M: "Japanese Treefrog Experiment Onboard The Space Station MIR." Proc.of Satellite Symp.4: COSY-8,Munich. 365-369 (1992)
[Publications] Takahashi K: "Polarity in spontaneous unwinding after prior rotation of the flagellar beat plane in sea-urchin spermatozoa." J.Cell Sci.98. 183-189 (1991)
[Publications] Kawasaki Y: "Growth of the Cellular Slime Mold Dictyostelium discoideum,is Gravity dependent." Plant Physiol.93. 1568-1572 (1990)
[Publications] Murakami A: "Behavioral responses of Paramecium to Gravity." Proc.17th Int.Symp.Space Technol.Sci.2087-2089 (1990)
[Publications] Yamashita M: "Telescience Testbed for Physiological Experiments in Space." Microgravity Q. 1. 1-8 (1990)

1994 Fiscal Year Annual Research Report

長期宇宙滞在による生体の機能と形態への影響

Principal Investigator

渡邉 悟 名古屋大学, 環境医学研究所, 教授 (00021361)

Research Products

[Publications] Watanabe S: "Paraboric flight experiments on physiological data acquisition and processing technologies using small jet aircraft (MU300)." J.of Grav.Physiol.1(1). 92-95 (1994)

[Publications] Watanabe S: "Telescience testbed experiments for biomedical studies: Fertilization potential recording of amphibian eggs using tele-manipulation under stereoscopic vision." Acta Astronautica. 33. 189-194 (1994)

[Publications] Kato T Jr: "Cloning of a marsupial DNA photolyase gene and the lack of related nucleotide sequences in placental mammals." Necleic.Acids.Res.20. 4119-4124 (1994)

[Publications] 井尻 憲一: "微小重力下におけるメダカの行動" 宇宙航空環境医学. 31. 20-23 (1994)

[Publications] 井尻 憲一: "メダカの宇宙における飼育と発生学実験の基礎実験" パラボリックフライト. 4(1). 21-28 (1994)

[Publications] Nitta K: "Possible Contributions to Earth Science Program and Others." Adv.Space Res.14. 125-134 (1994)

[Publications] Gunge N: "UV hypersensitivity of yeast linear plasmids." Current Genetics. 26. 369-373 (1994)

[Publications] Matsumoto H: "p53 proteins accumulated by heat stress associate with heat shock proteins HSP72/HSC73 in human glioblastoma cell lines." Cancer Lett.87. 39-46 (1994)

[Publications] Masuda Y: "Changes in the rheological properties of the cell wall of plant seedlings under simulated microgravity conditions." Biorheo.31. 171-177 (1994)

[Publications] 河崎 行繁: "地球外微生物の探査." 日本宇宙生物科学学会会誌 宇宙生物科学. 8. 103-112 (1994)

[Publications] 古賀 一男: "宇宙空間における視覚安定性の研究" 宇宙生物科学. 7(4). 333-339 (1994)

[Publications] 古賀 一男: "宇宙実験に随伴する困難な技術的問題" 光学. 23(1). 111-115 (1994)

[Publications] Abe K: "Graviresponding sites on shoots of normal and ｀lasy´ rice seedings." Physiologia plantarum. 92. 371-374 (1994)

[Publications] Mori S: "Visuo-vestibular adaptaion in fish under prolonged microgravity." Proc.of 19th Int.Symp.Space Technol.Sci.879-881 (1994)

[Publications] Mori S: "Space experiment using large-sized fish: in case of carp in Spacelab-J mission." Acta Astronautica. 33. 41-47 (1994)

[Publications] Arao T: "Biosynthesis of polyunsaturated lipids in the diatom,Paeodactylm tricornutum." Phytochem.36. 629-635 (1994)

[Publications] Hotta T: "Interrelationship between O^6-alkylguanine-DNA alkyltransferase activity and susceptibility to chloroethylnitrosoureas in several glioma cell lines." J.Neuro-Oncol.17. 1-8 (1993)

[Publications] Hoson T: "Vegetative growth of higher plants on a three-dimensional clinostat." Micrograv.Sci.Technol.6. 278-281 (1993)

[Publications] Suge H: "Effect of cytokinin and anticytokinin on the tillering of barley." Jpn.J.Crop Sci.62. 595-600 (1993)

[Publications] Mogami Y: "Beating of cilia of sea urchin embryos: a critical comparison of the normal and reversed beating of cilia of isolated cells." J.Exp.Biol.175. 251-266 (1993)

[Publications] Yamada M: "Plant growth under clinostat-microgravity condition." Biological Sci.in Space. 7(2). 116-119 (1993)

[Publications] Takabayashi A: "Posture control of fish related to gravity input." Proc.of 18th Int.Symp.Space Technol.Sci.2059-2063 (1992)

[Publications] Takabayashi A: "Effects of visual and vestibular apparates lesions on goldfish dorsal light response." Environ.Med.36. 187-190 (1992)

[Publications] Otsubo K: "Carbon Dioxide Adsorption Characteristics of Solid Amine." Proc.of 18th Int.Symp.Space Technol.Sci.1431-1438 (1992)

[Publications] Bauker R: "Gravity-controlled gliding velocity in Loxodes." Eur.J.Protistol.28. 238-245 (1992)

[Publications] Machemer H: "Short-term microgravity to isolate graviperception in cells." Micrograv.sci.technol.3. 119-123 (1992)

[Publications] Mogami Y: "Regulation of ciliary movement in sea urchin embryos: dopamine and 5-HT change the swimming behaviour." Comp.Biochem.Physiol.101C. 251-254 (1992)

[Publications] Yamashita M: "Japanese Treefrog Experiment Onboard The Space Station MIR." Proc.of Satellite Symp.4: COSY-8,Munich. 365-369 (1992)

[Publications] Takahashi K: "Polarity in spontaneous unwinding after prior rotation of the flagellar beat plane in sea-urchin spermatozoa." J.Cell Sci.98. 183-189 (1991)

[Publications] Kawasaki Y: "Growth of the Cellular Slime Mold Dictyostelium discoideum,is Gravity dependent." Plant Physiol.93. 1568-1572 (1990)

[Publications] Murakami A: "Behavioral responses of Paramecium to Gravity." Proc.17th Int.Symp.Space Technol.Sci.2087-2089 (1990)

[Publications] Yamashita M: "Telescience Testbed for Physiological Experiments in Space." Microgravity Q. 1. 1-8 (1990)

渡邉悟名古屋大学, 環境医学研究所, 教授 (00021361)

[Publications] 井尻憲一: "微小重力下におけるメダカの行動" 宇宙航空環境医学. 31. 20-23 (1994)

[Publications] 井尻憲一: "メダカの宇宙における飼育と発生学実験の基礎実験" パラボリックフライト. 4(1). 21-28 (1994)

[Publications] 河崎行繁: "地球外微生物の探査." 日本宇宙生物科学学会会誌宇宙生物科学. 8. 103-112 (1994)

[Publications] 古賀一男: "宇宙空間における視覚安定性の研究" 宇宙生物科学. 7(4). 333-339 (1994)

[Publications] 古賀一男: "宇宙実験に随伴する困難な技術的問題" 光学. 23(1). 111-115 (1994)