1995 Fiscal Year Final Research Report Summary
Catalytic Asymmetric Synthesis of Bioactive Molecules with a Benzylic Quarternary Carbon
| Project/Area Number |
06453188
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| Research Category |
Grant-in-Aid for General Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Chemical pharmacy
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| Research Institution | University of Tokyo |
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Principal Investigator |
SHIBASAKI Masakatsu University of Tokyo, Fac.of Pharm., Professor, 薬学部, 教授 (30112767)
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| Co-Investigator(Kenkyū-buntansha) |
SASAI Hiroaki University of Tokyo, Fac.of Pharm., Associate Professor, 薬学部, 助教授 (90205831)
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| Project Period (FY) |
1994 – 1995
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| Keywords | Asymmetrtic Catalyst / Heck Reaction / Palladium |
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| Research Abstract |
We have developed a catalytic asymmetric construction of benzylic quarternary carbons. The strategy utilizes an asymmetric Heck reaction. By using this method, we have achieved catalytic asymmetric syntheses of bioactive molecules such as eptazocine, capnellene and halenaquinol.
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Research Products
(10 results)
