1996 Fiscal Year Final Research Report Summary
Development of a PET-measuring system for the monkey brain.
| Project/Area Number |
06508004
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 試験 |
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| Research Field |
Neuroscience in general
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| Research Institution | Dept.of Social & Information Sciences, NIHON FUKUSHI UNIVERSITY (1995-1996)
Kyoto University (1994) |
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Principal Investigator |
KUBOTA Kisou NIHON FUKUSHI UNIVERSITY,Dept.of Social & Information, Professor., 情報社会科学部, 教授 (30027479)
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| Co-Investigator(Kenkyū-buntansha) |
ANDO Ichirou Hamamatsu Photonics, Central Institute, Research staff., 中央研究所, 研究員
OKADA Hiroyuki Hamamatsu Photonics, Central Institute, Research Head., 中央研究所, 専任部員
SAWAGUCHI Toshiyuki Hokkaido University, Dept.of Literature, Associate Professor., 文学部, 助教授 (00183830)
MIKAMI Akichika Kyoto University, Primate Research Institute, Professor., 霊長類研究所, 教授 (40027503)
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| Project Period (FY) |
1994 – 1996
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| Keywords | PET / GO / NO-GO Task / Rhesus Monkey / Temporal Lobe / Entorhinal Cortex |
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| Research Abstract |
While two rhesus monkeys were performing a simple visual reaction Lime task and a visually guided GO/NO-GO task with symmetrical reinforcement, a PET measurement was performed. Systems to let the monkey, sitting in a primate chair, perform the learned task and collect data of activity changes of the local blood flow with 0-15 water were completed. Continuous histology sections of the brain of two monkeys with Nissl stains were also completed. Therefore, mcasuremenltof the local blood flow during the task performance were successfully conducted and cytoarchitectural identifications of activated areas became possible. During a visual reaction time task, in addition to the conventional areal acrivation of the contralateral hand motor area, bilateral motor association areas (areas 6), and contralateral area 46 were activated. During a GO/NO-GO task, colored cue stimuli induced activations of the inferotemporal cortex (area 22) and entorhinal certex and hippocampal-parahipocampal gyri, suggesting their activation to remember the color and succeeding performance, and activation of the contralateral motor area, area 8 and preSMA,indicating their activations for selection of the GO or NO-GO performance.
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[Publications] Mikami,A.,Ando,I.,Kubota,K.,Sawaguchi,T.,Yoshikawa,E.,Kakiuchi,T.,Nakamura,K.,and Tsukada,H.: "Posterior cortical areas activated during visually-guided GO/NO-GO task : a PET study." Neurosci. Abs.22. 401- (1996)
Description
「研究成果報告書概要(和文)」より
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