1995 Fiscal Year Final Research Report Summary
Development of analyzing and imaging system of three-dimensional brain functional mapping for diagnosis and treatment evaluation of language and cognitive disorders
| Project/Area Number |
06558120
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| Research Category |
Grant-in-Aid for Developmental Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | University of Tokyo |
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Principal Investigator |
ITOH Kenji University of Tokyo, Faculty of Medicine, Assis Prof, 医学部(医), 助手 (80010106)
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| Co-Investigator(Kenkyū-buntansha) |
KOSHIDA Ichiro Tokyo Institute of Engineering Sience, Assoc Pfor, 工学部, 助教授 (00192055)
YUMOTO Masato University of Tokyo, Faculty of Medicine, Assis Prof, 医学部(病), 助手 (30240170)
FUKUDA Masato University of Tokyo, Faculty of Medicine, Assis Prof, 医学部(病), 助手 (20221533)
HIRAMATSU Kenichi University of Tokyo, Faculty of Medicine, Assis Prof, 医学部(病), 助手 (50218814)
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| Project Period (FY) |
1994 – 1995
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| Keywords | Event-related potentials / Electroencephalography / Magnetoencephalography / Topography / 3D construction / Functional localization / Dipole / Language |
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| Research Abstract |
We investigated and got following results on the development of analyzing and imaging system of three-dimensional brain functional mapping for diagnosis and treatment evaluation of language and cognitive disorders.
1.For developing a method of three-dimensional brain functional localization based on neurosynaptic circuit model, we tried three-dimensional functional localization by use of a scalp current density method on spherical cortex in the cortico-subcortical model.
2.For developing a testing paradigm of functional localization in verbal and cognitive deficits, we implemented a program of instructing strategies on paradigms for verbal and cognitive functions.
3.For establishing a evaluation method of treatment as well as rehabilitation of verbal and cognitive deficits, we proposed a method of subjective evaluation on instructed learning and drug treatment based on their data base.
4.For establishing a method of diagnosis with brain functional localization, we proposed a method of diagnosis using a interactive system of navigating images in archives of MRI/fMRI 3D tomographic data, EEG spherical topography, and MEG current source.
5.For developing a routine of analyzing and imaging 3D brain functional localization, we completed a program of analyzing and imaging pictures from data objects in object-oriented programming language (C^<++>).
6.For applying the analyzing and imaging system of three-dimensional brain functional mapping to clinical use, we completed the system of multi-channel data input system with analyzing system of 3D brain functional localization.
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