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1995 Fiscal Year Final Research Report Summary

Effect of endurance training on autonomic reflexes in humans

Research Project

Project/Area Number 06670092
Research Category

Grant-in-Aid for General Scientific Research (C)

Allocation TypeSingle-year Grants
Research Field Environmental physiology (including Physical medicine and Nutritional physiology)
Research InstitutionUniversity of Occupational and Environmental Health

Principal Investigator

SAGAWA Sueko  Department of Physiology school of Medicine, University of Occupational and Environmental Health, Associate Professor, 医学部, 助教授 (20035489)

Project Period (FY) 1994 – 1995
Keywordsbaroreflex / LBNP / carotid baroreceptors / R-R interval / neck chamber / athlete
Research Abstract

There is evidence suggesting that endurance-trained athletes (ET) fail to maintain blood pressure responses to gravitational challenges such as head-up tilt, standing, or lower body negative pressure (LBNP). The purpose of the present study was to examine whether gravitational intolerance in ET was due to a blunted carotid baroreceptor-cardiac responsiveness. Twenty ET females (long distance runner, 18.4<plus-minus>2.2y.o) and 9 endurance-untrained female (UT,20.4<plus-minus>0.9y.o.) underwent a 21-min bout of graded LBNP (0 to -60mmHg). Sixty % of ET group showed presyncopal symptoms during LBNP,whereas only 22% of UT became presyncopic. Carotid baroreceptor-cardiac responses were estimated by using a neck chamber. R-R intervals were plotted against carotid distending pressures and the response was analyzed by applying a four-parameter sigmoidal logistic function. The maximal gain of the curve in ET group was greater (P<0.05) than that of UT group, indicating increased baroreflex sensitivity. The centering point of the curve, an indicator of the operating point, was identical. There was a significant correlation between VO_2max and maximal gain (r=0.693, P<0.005). These results may suggest that attenuated baroreflex control of the heart rate in ET is not responsible for the mechanisms of the gravitational intolerance.

  • Research Products

    (4 results)

All Other

All Publications (4 results)

  • [Publications] Sagawa, K. Shiraki, R. Tori, et al.: "Effect of altitude exposure on carotid baroreceptor-cardiac reflexes." FASEB J.9(4). A648 (1995)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Sagawa, K. Shiraki, F. Yamazaki, et al.: "Carotid baroreceptor-cardiac resoponsiveness to lower body negative pressure in female long distance runners." FASEB J.10(4)(in press). (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Sagawa, K.Shiraki, R.Torii, F,wada, K.Nagaya, and Y.Endo: "Effect of altitude exposure on carotid baroreceptor-cardiac reflexes." FASEB J.9(4). A648 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Sagawa, K.Shiraki, F.Yamazaki, R.Torii, Y.Endo, and T.Morikawa.: "Carotid baroreceptor-cardiac responsiveness to lower body negative pressure in female long distance runners." FASEB J.10(4). in press (1996)

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 1997-03-04  

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