• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to project page

1996 Fiscal Year Final Research Report Summary

Clinico-psychopathological and brain imaging studies in atypical psychosis

Research Project

Project/Area Number 06670984
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Psychiatric science
Research InstitutionAichi Medical University

Principal Investigator

HAYASHI Takuji  Aichi Medical University, Dep.of Psychiatry, Associate professor, 医学部, 助教授 (80173011)

Co-Investigator(Kenkyū-buntansha) SUGA Hidemichi  Aichi Medical University, Dep.of Psychiatry, Lecturer, 医学部, 講師 (70187623)
OHARA Mitsugi  Aichi Medical University, Dep.of Psychiatry, Professor, 医学部, 教授 (40065537)
Project Period (FY) 1994 – 1996
KeywordsSchizophrenia / Atypical psychosis / IMP-SPECT / Clinical symptom / Family history / ICD-10 / 誘因 / 家族負因
Research Abstract

In order to reconsider atypical psychosis (Mitsuda) using ICD-10 criteria, we investigated 351 patients with psychotic symptoms, who were admitted to the psychiatric ward of Aichi Medical University Hospital from 1982 to 1991. These patients were diagnosed by the criteria of Mitsuda and ICD-10 (JCM : Japanese clinical modification), respectively, and the clinical features, family history and precipitating factors (judged to be colsely related to the onset of the illness) were examined. The results obtained are as follows.
1) Atypical psychoses in either criteria are mainly composed of acute transient psychotic disorder (F23) and schizoaffective psychosis (F25). However, there are some differences between the two diagnostic systems. Atypical psychosis (JCM) excludes and acute schizophrenia-like psychotic disorder (F23.2). On the other hand, Mitsuda's atypical psychosis includes these psychoses.
2) Schneider's first-rank symptoms are frequently found not only in schizophrenics but in atypi … More cal psychotics. Auditory hallucinations and self-disturbances are more frequently encountered in schizophrenics, whereas delusional perception is more frequently found in atypical psychotics.
3) Atypical psychosis (Mitsuda) patients have more first-degree relatives with psychiatric disorders than schizophrenics. On the other hand, atypical psychosis (JCM) patients have significantly more relatives with psychiatric disorders, especially with affective disorders, than schizophrenics.
4) Precipitating factors were found more frequently in both categories of patients with atypical psychosis than in schizophrenics.
5) On the subdivisions of atypical psychosis, acute schizophrenia-like psychotic disorder (ICD : F23.2) patients have less family history than the other acute psychoses patients and schizophrenics, As for preipitating factors, they have them more frequently than the other acute psychoses patients, especially schizophrenics. On the contrary, patients with acute polymorphic psychotic disorder with symptoms of schizophrenia (F23.1) have more family history and fewer precipitating factors. Therefore, these two subtypes of atypical psychosis seem to have contrasting positions.
The present studies suggest that atypical psychosis is different disease entity from schizophrenia, and that this pyschosis is not homogeneous disease, therefore, further subclasification is warranted. Less

  • Research Products

    (12 results)

All Other

All Publications (12 results)

  • [Publications] 須賀英道 他: "画像による非定型精神病の診断的位置づけ" 精神医学. (発表予定).

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 堀田典裕、林 拓二 他: "急性精神病の遷延性経過について" 分裂病研究の進歩. (発表予定).

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 林 拓二、安藤琢弥 他: "分裂病と非定型精神病(満田)の精神症状と経過について" 精神医学. 38. 27-35 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 林 拓二、須賀英道 他: "分裂病と非定型精神病(満田)の発症年齢と性差について" 精神医学. 37. 1255-1263 (1995)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 林 拓二、安藤琢弥 他: "分裂病と非定型精神病(満田)の負因と誘因の相違について" 愛知医科大学医学会雑誌. 23. 321-331 (1995)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 須賀英道 他: "非定型精神病の画像診断的研究-SPECTによる画像解析を中心にして-" こころの臨床. 14. 48-52 (1995)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 林 拓二: "精神医学レビュー'97(その他の非定型精神疾患)" 総合医学社(発表予定), (1997)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 林 拓二 他: "精神科症例集、4巻「躁うつ病・非定型精神病」" 中山書店, 12 (1994)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] SUGA,H.: "Single photon emission commputed tomography (SPECT) findings using N-isopropyl-p [123I] iodoamphetamine [123I-IMP] in schizophrenia and atypical psychosis"

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] HAYASHI,T.: "Sex difference and age at onset on schizophrenia and atypical psychosis." Seisin-igaku. 37. 1255-1263 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] HAYASHI,T.: "Clinical symptom an course on schizophrenia and atypical psychosis." Seisin-igaku. 38. 27-35 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] HAYASHI,T.: "Family history and precipitating factor on schizophrenia and atypical psychosis." J.Aichi Med.Univ.Assoc.23. 321-331 (1995)

    • Description
      「研究成果報告書概要(欧文)」より

URL: 

Published: 1999-03-09  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi