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[Publications] Nishizuka,Y.: "Protein kinase C and lipid signaling for sustained cellularresponses." FASEB J.(in press). (1995)
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[Publications] Tsujishita,Y.,Asaoka,Y.,Nishizuka,Y.: "Regulation of phospholipase A2 in human leukemia cell lines:its implication for intracellular signaling." Proc.Natl.Acad.Sci.USA. 91. 6274-6278 (1994)
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[Publications] Matsushima,S.,Nakamura,S.: "Protein kinase Cδ-and ε-subspecies in rat central nervous tissues;differential distribution and phorbol ester-induced redistribution in synaptosomes." Neurosci.Res.19. 339-343 (1994)
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[Publications] Nakamura,S.,Nishizuka,Y.: "Lipid mediators and protein kinase C activation for intracellular signaling network." J.Biochem.115. 1029-1034 (1994)
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[Publications] Nakamura,S.,Asaoka,Y.,Hullin,F.,Nishizuka,Y.: "Lipid second messenger and protein kinase C for intracellular signalling." Pharmacol.Rev.(in press). (1995)
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[Publications] Ouahchi,K.,Arita,M.,Kayden,H.,Hentani,F.,Ben,M.,Hamida,M.B.,Sokoi,R.,Arai,H.,Inoue,K.,Mandel,J.L.,Koenig,M.: "Ataxia with isolated vitamin E deficiency is caused by mutation in the alpha-tocopherol transfer protein." Nature Genetics. 9. 141-145 (1995)
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[Publications] Fukasawa,M.,Hirota,K.,Adachi,H.,Mimura,K.,Murofushi-Murakami,K.,Tsujimoto,M.,Arai,H.,Inoue,K.: "Chinese hamster ovary cells expressing a novel type of acetylated LDL receptor." J.Biol.Chem.270. 1921-1927 (1994)
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[Publications] Hattori,M.,Adachi,H.,Tsujimoto,M.,Arai,H.,Inoue,K.: "Miller-Dieker lissencephaly gene encodes a subunit of brain platelet-activating factor acetylhydrolase." Nature. 370. 216-218 (1994)
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[Publications] Hattori,M.,Adachi,H.,Tujimoto,M.,Arai,H.,Inoue,K.: "The catalytic subunit of bovine brain platelet-activating factor acetylhydrolase is a novel type of serine esterase." J.Biol.Chem.269. 23150-23155 (1994)
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[Publications] Nakatani,Y.,Murakami,M.,Kudo,I.,Inoue,K.: "Dual regulation of cytosolic phospholipase A2 in mast cells after cross-linking of Fc epsilon-receptor." J.Immunol.153. 796-803 (1994)
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[Publications] Shikano,M.,Masuzawa,Y.,Yazawa,K.,Takayama,K.,Kudo,I.,Inoue,K.: "Complete discrimination of docosahexanoate from arachidonate by 85kDa cytosolic phospholipase A2 during the hydrolysis of diacyl alkenylacylglycerophosphoethanolamine." Biochem.Biophys.Acta. 1212. 211-216 (1994)
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[Publications] Inoue,K.,Arai,H.,Hattori,M.: "PAF acetylhydrolase from mammalian tissues." J.Lipid Mediator Cell Signalling. 10. 13-16 (1994)
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[Publications] Reza,F.,Igarashi,K.,Tokita,S.,Asai,K.,Aoki,J.,Asaoka,Y.,Umeda,M.,Inoue,K.: "Antiidiotypic monoclonal antibody recognizes a consensus recognition site for phosphatidylserine in phosphatidylserine-specific monoclonal antibody and protein kinase C." FEBS Lett.339. 229-233 (1994)
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[Publications] Takahashi,Y.,Taketani,Y.,Endo,T.,Yamamoto,S.,Kumegawa,M.: "Studies on the induction of cyclooxygenase isozymes by various prostaglandins in mouse osteoblastic cell line with reference to signal transduction pathways." Biochim.Biophys.Acta. 1212. 217-224 (1994)
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[Publications] Handa,Y.,Hatanaka,K.,Saito,M.,Majima,M.,Ogino,M.,Kawamura,M.,Ohno,T.,Yang,Q.,Katori,M.,Yamamoto,S.: "Detection of inducible prostaglandin H synthase-2 in cells in the exudate of rat carrageenin-induced pleurisy." Biomed.Res.15. 127-130 (1994)
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[Publications] Handa,T.,Hagiya,H.,Suzuki,H.,Arakawa,T.,Nakamura,M.,Matsuda,S.,Yoshimoto,T.,Yamamoto,S.,Azekawa,T.,Morita,y.,Ishimura,K.,Kim,H.-Y.: "Arachidonate 12-lipoxygenase of rat pineal glands:catalytic properties and primary structure deduced from its cDNA." Biochim.Biophys.Acta. 1211. 221-228 (1994)
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[Publications] Reddy,R.G.,Yoshimoto,T.,Yamamoto,S.,Funk,C.D.,Marnett,L.J.: "Expression of porcine leukocyte 12-lipoxygenase in a baculovirus/insect cell system and its characterization." Arch.Biochem.Biophys.312. 219-226 (1994)
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[Publications] Gu,J.-L.,Natarajan,R.Ben-Ezra,J.,Valente,G.,Scott,S.,Yoshimoto,T.,Yamamoto,S.,Rossi,J.J.,Nedler,J.L.: "Evidence that a leukocyte type of 12-lipoxygenase is expressed and regulated by angiotensin II in human adrenal glomerulosa cells." Endocrinology. 134. 70-77 (1994)
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[Publications] Liu,Y.-W.,Asaoka,Y.,Suzuki,H.,Yoshimoto,T.,Yamamoto,S.,Chang,W.-C.: "Induction of 12-lipoxygenase expression by epidermal growth factor is mediated by protein kinase C in A431 cells." J.Pharmacol.Exp.Ther.271. 567-573 (1994)
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[Publications] Alanko,J.,Kurahashi,Y.,Yoshimoto,T.,Yamamoto,S.,Baba,K.: "Panaxynol,a polyacetylene compound isolated from oriental medicines,inhibits mammalian lipoxygenases." Biochem.Pharmacol.48. 1979-1981 (1994)
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[Publications] Banno,Y.,Nakashima,S.,Hachiya,T.,Nozawa,Y.: "Endogenous cleavage of phospholipase Cβ3 by agonist-induced activation of calpain in human platelets." J.Biol.Chem.(in press). (1995)
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[Publications] Liu,B.,Nakashima,S.,Kanoh,H.,Takano,T.,Shimizu,T.,Nozawa,Y.: "Activation of phospholipase D in Chinese hamster ovary cells expressing platelet-activating factor receptor." J.Biochem.116. 882-891 (1994)
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[Publications] Banno,Y.,Okano,Y.,Nozawa,Y.: "Thrombin-mediated phosphoinositide hydrolysis in Chinese hamster ovary cells overexpressing phospholipase C." J.Biol.Chem.269. 15846-15852 (1994)
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[Publications] Hashii,M.,Hirato,M.,Ozeki,S.,Nozawa,Y.,Higashida,H.: "Ca^<2+> influx gated by inositol-3,4,5,6-tetrakisphosphate in NIH/3T3 fibroblasts.Biochem.Biophys." Res.Commun.200. 1300-1306 (1994)
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[Publications] Nakashima,S.,Nozawa,Y.: "Receptor-mediated phospholipase D activation in secretory cells." In Lipid Mediators in Health and Disease (edited by Zor,U.),Freund Publishing House Ltd.,London. pp65-69 (1994)
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[Publications] Kumada,S.,Nakashima,S.,Miyata,H.,Nozawa,Y.: "Potent activation of phospholipase D by phenylarsine oxide in rat basophilic leukemia(RBL-2H3)cells." Biochem.Biophys.Res.Commun.199. 792-798 (1994)
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[Publications] Banno,Y.,Asano,T.,Nozawa,Y.: "Proteolytre modification of membrane-associated phospholipase C-β by μ-calpain chances its activation by G-protein βγ subunits in human platelets." FEBS Lett.340. 185-188 (1994)
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[Publications] Osada,S.,Okano,Y.,Saji,S.,Nozawa,Y.: "Spontaneous Ca^<2+> release from a caffeine and ryanodine-sensitive intact cellular Ca^<2+> store in freshly prepared hepatocytes." Hepatology. 19. 514-517 (1994)
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[Publications] Sugiyama,T.,Sakai,T.,Nozawa,Y.,Oka,N.: "Prostaglandin F2α-stimulated phospholipase D activation in osteoblast-like MC3T3-E1 cells Involvement in sustained 1,2-diacylglycerol production." Biochem.J.,. 298. 479-484 (1994)
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[Publications] Nakashima,S.,Chatani,Y.,Nakamura,M.,Miyoshi,N.,Kohno,M.,Nozawa,Y.: "Tyrosine phosphorylation and activation of mitogen-activated protein kinases by thrombin in human platelets:Possible involvement in late arachidonic acid release." Biochem.Biophys.Res.Commun.198. 497-503 (1994)
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[Publications] Handa,K.,Nishijima,M.,Akamatsu,Y.,Pagano,D.: "Both sphingolipids and cholesterol participate in the detergent insolubility of alkaline phosphatase,a glycosyl phosphatidylinositolanchored protein,in mammalian membranes." J.Biol.Chem.(in press). (1995)
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[Publications] Pugin,J.,Heumann,D.,Tomasz,A.,Kravchenko,V.V.,Akamatsu,Y.,Nishijima,M.,Glauser,M.P.,Tobias,P.S.,Ulevitch,R.J.: "CD14 is a pattern recognition receptor." Immunity. 1. 509-516 (1994)
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[Publications] Nishijima,M.,Hara-Kuge,S.,Takasuka,N.,Akagawa,K.,Setouchi,M.,Matsuura,K.,Yamamoto,S.,Akamatsu,Y.: "Identification of a biochemical lesion,and characteristic response to lipopolysaccharide(LPS)of a cultured macrophage-like cell mutant with defective LPS-binding." J.Biochem.116. 1082-1087 (1994)
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[Publications] Takata,M.,Sabe,H.,Hata,A.,Inazu,T.,Homma,Y.,Nukada,T.,Yamamura,H.,Kurosaki: "T.Tyrosine kinase Lyn and Syk regulate the B cell receptor-coupled Ca^<2+> mobilization through the distinct pathways." EMBO J.13. 1341-1349 (1994)
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[Publications] Sada,K.,Yanagi,S.,Yamamura,H.: "Activation of p72^<syk> by thrombin in a cell-free system." Biochem.Biophys.Res.Commun.200. 1-7 (1994)
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[Publications] Kurosaki,T.,Takata,M.,Yamanashi,Y.,Inazu,T.,Taniguchi,T.,Yamamoto,T.,Yamamura,H.: "Sky activation by the src-family tyrosine kinase in the B cell receptor signaling" J.Exp.Med.179. 1725-1729 (1994)
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[Publications] Tsubokawa,M.,Yanagi,S.,Sada,K,Nakamura,S.,Saitou,H.,Yamamura,H.: "CPTK71,a cytosolic protein tyrosine kinase previously purified from bovine platelets,is identical with p72^<syk>.Biochem." Biophys.Res.Commun.200. 1592-1597 (1994)
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[Publications] Yang,C.,Yanagi,S.,Wang,X.,Taniguchi,T.,Sakai,K,Yamamura,H.: "Purification and characterization of a protein-tyrosine kinase p72^<syk> from porcine spleen." Eur.J.Biochem.221. 973-978 (1994)
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[Publications] Qin,S.,Inazu,T.,Yang,C.,Sada,K.,Taniguchi,T.,Yamamura,H.: "Interleukin 2 mediates p72^<syk> activation in peripheral blood lymphocytes." FEBS Lett.345. 233-236 (1994)
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[Publications] Yanagi,S.,Sada,K.,Tohyama,Y.,Tsubokuwa,M.,Nagai,K.,Yonezawa,K.,Yamamura,H.: "Translocation,activation,and association with PI3 kinase of p72^<syk> are early events during platelet activation" Eur.J.Biochem.224. 329-333 (1994)
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[Publications] Wang,X.,Sada,K,Yanagi,S.,Yang,C.,Rezaul,K.,Yamamura,H.: "Intracellular calcium dependent activation of p72^<syk> in platelets." J.Biochem.116. 858-861 (1994)
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[Publications] Nagai,K.,Inazu,T.,Yamamura,H.: "p72^<syk> is activated by vanadate plus H_2O_2 in porcine platelets and phosphorylates GTP ase activating protein on tyrosine residue(s)." J.Biochem.116. 1176-1181 (1994)
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[Publications] Fujii,C.,Yanagi,S.,Sada,K.,Nagai,K,Taniguchi,T.,Yamamura,H.: "Involvement of proteintyrosine kinase p72^<syk> in collagen-inducedsignal transduction in platelets." Eur.J.Biochem.226. 243-248 (1994)
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[Publications] Tohyama,Y.,Yanagi,S.,Sada,K.,Yamamura,H.: "Translocation of p72^<syk> to the cytoskeleton in thrombin-stimulated platelets." J.Biol.Chem.269. 32796-32799 (1994)
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[Publications] Karim,R.,Yanagi,S.,Sada,K,Taniguchi,T.,Yamamura,H.: "Protein tyrosine kinase p72^<syk> is activated by platelet activating factor in platelets." Thromb.Haemost.72. 937-941 (1994)
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[Publications] Ohmichi,M.,Matuoka,K.,Takenawa,T.,Saltiel,A.R.: "Growth factors differentially stimulate the phosphorylation of Shc proteins and their association with Grb2 in PC12 pheochromocytoma cells." J.Biol.Chem.269. 1143-1148 (1994)
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[Publications] Fukami,K.,Endo,T.,Inamura,M.,Takenawa,T.: "α-Actinin and vinculin are PIP2-binding proteins involved in signaling by tyrosine kinase." J.Biol.Chem.269. 1518-1522 (1994)
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[Publications] Tsubokawa,H.,Oguro,K.,Robinson,H.P.C.,Matuzawa,T.,Rhee,S.G.,Takenawa,T.,Kawai,N.: "Inositol 1,3,4,5-tetrakisphosphate as a mediator of neuronal death inis chemic hippocampus." Neroscience. 59. 291-297 (1994)
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[Publications] Shimazaki,K.,Ishida,A.,Rhee,S.G.,Takenawa,T.,Kawai,N.: "Changes in IP3 3-kinase immunoreactivity following transient ischeamia in gerbil hippocampus." NeuroReport. 5. 758-788 (1994)
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[Publications] Asano,M.,Koizumi,K.,Homma,Y.,Takenawa,T.,Nimura,Y.,Kojima,K.,Yoshida,S.: "Purification and characterization of nuclear phospholipase C specific for phosphoinositides" J.Biol.Chem.269. 12360-12366 (1994)
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[Publications] Miki,H.,Miura,K.,Matuoka,K.,Nakata,T.,Hirokawa,N.,Orita,S.,Kaibuchi,K.,Takai,Y.,Takenawa,T.: "Association of ash/grb-2 with dynamin through the src homology 3 domam" J.Biol.Chem.269. 5489-5492 (1994)
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[Publications] Nakanishi,H.,Orita,S.,Kaibuchi,K.,Miura,K.,Miki,H.,Takenawa,T.,Takai,Y.: "Kinetic properties of ash/grb2-interacting GDP/GTP exchange protein" Biochem.Biophys.Res.Commun.198. 1255-1261 (1994)
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[Publications] Hashimoto,Y.,Matuoka,K.,Takenawa,T.,Muroya,K.,Hattori,S.,Nakamura,S.: "Different interactions of grb2/ash molecule with NGF and EGF receptors in rat pheochromocytoma PC12 cells." Oncogene. 9. 869-875 (1994)
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[Publications] Tanaka,S.,Morishita,T.,Hashimoto,Y.,Hattori,S.,Nakamura,S.,Shibuya,M.,Matuoka,K.,Takenawa,T.,Kurata,T.,Nagashima,K.,Matsuda,M.: "C3G,a guanine nucleotide-releasing protein expressed ubiquitously,binds to the src homology 3 domains of crk and grb2/ash proteins." Proc.Natl.Acad.Sci.USA. 91. 3443-3447 (1994)
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[Publications] Ando,A.,Yonezawa,K.,Gout,I.,Nakata,T.,Ueda,H.,Hara,K.,Kitamura,Y.,Noda,T.,Takenawa,T.,Hirokawa,N.,Waterfield,M.,Kasuga,M.: "A complex of grb2-dynamin binds to tyrosine-phosphorylated insulin receptor substrate-1 after insulin treatment." EMBO J.13. 3033-3038 (1994)
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[Publications] Shibasaki,F.,Fukami,K.,Takenawa,T.: "Phosphatidylinositol 3-kinase binds to α-actinin through the p85 subunit." Biochem.J.302. 551-557 (1994)
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[Publications] Goto,H.,Tojo,A.,Muroya,K.,Hashimoto,Y.,Hattori,S.,Takenawa,T.,Yazaki,Y.,Shibuya,M.: "Epidermal growth factor-receptor mutants lacking autophosphorylation sites induces phosphorylation of Shc protein and Shc-association and retainsmitogenic activity." Proc.Natl.Acad.Sci.USA. 91. 167-171 (1994)
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[Publications] Okutani,T.,Okabayashi,Y.,Kido,Y.,Sugimoto,Y.,Sakaguchi,K.,Matuoka,K.,Takenawa,T.,Kasuga,M.: "Grb2/Ash bind sdirectly to tyrosine kinase 1068 and 1086 and indirectly to tyrosine 1148 of activated human epidermal growth factor receptors in intact cells." J.Biol.Chem.269. 31310-31314 (1994)
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[Publications] Fujimoto,J.,Yamamoto.T.: "brt,a mouse gene encoding a novel receptor type protein-tyrosine kinase,is preferentially expressed in the brain." Oncogene. 9. 693-698 (1994)
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[Publications] Umemori,H.,Sato,S.,Yagi,T.,Aizawa,S.,Yamamoto.T.: "Initial events of myelination involve Fyn tyrosine kinase signaling." Nature. 367. 572-576 (1994)
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[Publications] Hic,D.,Furuta,Y.,Suda,T.,Atsumi,T.,Ikawa,Y.,Fujimoto,J.,Yamamoto.T.,Aizawa,S.: "Inhibition of fibroblast-like cell differentiation by FAK-deficiency." Biochem.Biophys.Res.Commun.(in press). (1995)
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[Publications] Nakanishi,H.,Kaibuchi,K.,Orita,S.,Ueno,N.,Takai,Y.: "Different functions of smg GDP dissociation stimulator and mammalian counterpart of yeast Cdc25." J.Biol.Chem.269. 15085-15091 (1994)
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[Publications] Shimizu,K.,Kuroda,S.,Yamamori,E.,Matsuda,S.,Kaibuchi,K.,Yamauchi,T.,Isobe,T.,Irie,K.,Matsumoto,K.,Takai,Y.: "Synergistic activation by Ras and 14-3-3 protein of a MAP kinase kinase kinase named ERK kinase stimulator(ERKS)." J.Biol.Chem.269. 22917-22920 (1994)
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[Publications] Kuroda,S.,Shimizu,K.,Yamamori,E.,Matsuda,S.,Imazumi,K.,Kaibuchi,K.,Takai,Y.: "Purification and characterization of REKS from Xenopus eggs:identification of REKS as a rasdependent MEK kinase." J.Biol.Chem.(in press). (1995)
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[Publications] Wada,K.,Mizoguchi,A.,Kaibuchi,K.,Shirataki,H.,Ide,C.,Takai,Y.: "Localization of Rabphilin-3A,a putative target for Rab3A,at the sites of Ca^<2+>-dependent exocytosis in PC12 cells." Biochem.Biophys.Res.Commun.198. 158-165 (1994)
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[Publications] Jalink,K.,van Corven,E.J.,Hegeveld,T.,Morii,N.,Narumiya,S.,Moolenaar,W.: "Inhibition of lysophosphatidate-and thrombin-induced neurite regeneration and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein rho." J.Cell Biol.126. 801-810 (1994)
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[Publications] Rankin,S.,Morii,N.,Narumiya,S.,Rozengurt,E.: "Botulinum C3 exoenzyme blocks the tyrosine phosphorylation of p125^<FAK> and paxillin induced by bombesin and endothelin." FEBS Lett.354. 315-319 (1994)
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[Publications] Morii,N.,Narumiya,S.: "Preparation of native and recombinant botulinum C3 ADP-ribosylation." Methods Enzymol.(in press). (1995)
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[Publications] Tominaga,T.,Narumiya,S.: "Lymphocyte aggregation assay and inhibition by botulinum C3 ADP-ribosyltransferase." Methods Enzymol.(in press). (1995)
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[Publications] Seckl,M.,Morii,N.,Narumiya,S.,Rozengurt,E.: "GTPγS stimulates tyrosine phosphorylation of p125^<FAK> and paxillin in permeabilized Swiss 3T3 cells:role p21." J.Biol.Chem.(in press). (1995)
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[Publications] Nanmori,T.,Taguchi,W.,Kinugasa,M.,Oji,Y.,Sahara,S.,Fukami,Y.,Kikkawa,U.: "Purification and characterization of protein kinase C from a higher plant,Brassica campestris L." Biochem.Biophys.Res.Commun.203. 311-318 (1994)
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[Publications] Konishi,H.,Shinomura,T.,Kuroda,S.,Ono,Y.,Kikkawa,U.: "Molecular cloning of rat RAC protein kinase α and β,and their association with protein kinase Cζ.Biochem" Biophys.Res.Commun.205. 817-825 (1994)
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[Publications] Konishi,H.,Kuroda,S.,Kikkawa,U.: "The pleckstrin homology domain of RAC protein kinase associates with the regulatory domain of protein kinase Cζ." Biochem.Biophys.Res.Commun.205. 1770-1775 (1994)
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[Publications] Kasahara,K.,Kikkawa,U.: "Distinct effects of saturatedfatty acids on protein kinase C subspecies." J.Biochem.(in press). (1995)
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[Publications] Nakamura,F.,Kato,M.,Kameyama,K.,Nukuda,T.,Haga,T.,Kato,H.,Takenawa,T.,Kikkawa,U.: "Characterization of Gq family G proteins GL1α(G14α),GL2α(G11α),and Gqα expressed in the baculovirus-infected cell system." J.Biol.Chem.(in press). (1995)
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[Publications] Mukai,H.,Ono,Y.: "A novel protein kinase with leucine zipper-like sequences:its catalytic domain is highly homologous to protein kinase C." Biochem.Biophys.Res.Commun.199. 897-904 (1994)
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[Publications] Mukai,H.,Kitagawa,M.,Shibata,H.,Takanaga,H.,Mori,K.,Shimakawa,S.,Miyahara,M.,Hirao,K.,Ono,Y.: "Activation of PKN,a novel 120-KDa protein kinase with leucine zipper-like sequences,by unsaturated fatty acids and by limited proteolysis." Biochem.Biophys.Res.Commun.204. 348-356 (1994)
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[Publications] Ichikawa,S.,Hatanaka,H.,Takeuchi,Y.,Ohno,S.,Inagaki,F.: "Solution structure of cysteinerich domain of protein kinase Cα." J.Biochem.(in press). (1995)
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[Publications] Mizuno,K.Noda,K.,Ueda,Y.,Hanaki,H.,Saido,T-C.,Suzuki,K.,Ikuta,T.,Kuroki,T.,Tamaoki,T.,Hirai,S-I.,Osada,S.,Ohno,S.: "UCN-01,an anti-tumor drug,is a selective inhibitor of the conventional PKC subfamily" FEBS Lett.359. 259-261 (1995)
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[Publications] Hirano,M.,Hirai,S-I.,Mizuno,K.,Osada,S.,Hosaka,M.,Ohno,S.: "A protein kinase C isozyme,nPKCε is involved in the activation of NF-κB by 12-O-tetradecanoylphorbol-13-acetate(TPA)in rat 3Y1 fibroblasts." Biochem.Biophys.Res.Commun.206. 429-436 (1995)
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[Publications] Kim,H-M.,Hirota,S.,Chung,H-T.,Ohno,S.,Osada,S.,Shin,T.,Ko,K-I.,Kim,J-B.,Kitamura,Y.,Nomura,S.: "Dofferential expression of protein kinase C genes in cultured mast cells derived from normal and mast-cell-deficient mice and mast cell lines." Int.Arch.Allergy Immunol.105. 258-263 (1994)
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[Publications] Kim,H-M.,Hirota,S.,Chung,H-T.,Onoue,H.,Ito,A.,Morii,E.,Hirata,T.,Ohno,S.,Osada,S.,Kitamura,Y.,Nomura,S.: "PKC γ gene expression is delayed in postnatal central nervous system of mi/mi mice." J.Mol.Neurosci.4. 245-254 (1994)
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[Publications] Ikuta,T.,Chida,K.,Tajima,O.,Matsuura,Y.,Iwamori,M.,Ueda,Y.,Mizuno,K.,Ohno,S.,Kuroki,T.: "Cholesterol sulfate,a novel activator for the η isoform of protein kinase C." Cell Growth Differentiation. 5. 943-947 (1994)
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[Publications] Fujise,A.,Mizuno,K.,Ueda,Y.,Osada,S.,Hirai,S-I.,Takayanagi,A.,Shimizu,N.,Ohwada,K.,Nakajima,H.,Ohno,S.: "Specificity of the high affinity interaction of protein kinase C with a physiological substrate,myristoylated alanine-rich C kinase substrate,MARCKS." J.Biol.Chem.269. 31642-31648 (1994)
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[Publications] Kindregan,H.C.,Rosenbaum,S.E.,Ohno,S.,Niles,R.M.: "Characterization of conventional protein kinase C(PKC)isotype expression during F9 teratocarcinoma differentiation:Overexpression of PKC alpha alters the expression of some differentiation-dependent genes." J.Biol.Chem.269. 27756-27761 (1994)
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[Publications] Canzian,F.,Gariboldi,M.,Manenti,G.,Gregorio,L.,Osada,S.,Ohno,S.,Dragani,T-A.,Pierotti,M-A.: "Expression in lung tumors and genetic mapping of the novel murine protein kinase Cη." Mol.Carcinogenesis. 9. 111-113 (1994)
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[Publications] Kawabe,J-I.,Iwami,G.,Ohno,S.,Katada,T.,Ueda,Y.,Homcy,C.J.,Ishikawa,Y.: "Differential activation of adenylylcyclase by protein kinase C isoenzymes." J.Biol.Chem.269. 16554-16558 (1994)
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[Publications] Ohno,S.,Mizuno,K.,Adachi,Y.,Hata,A.,Akita,Y.,Akimoto,K.,Osada,S.,Hirai,S-I.,Suzuki,K.: "Activation of nPKCδ and ε upon mitogenic stimulation of quiescent rat 3Y1 fibroblasts." J.Biol.Chem.269. 17495-17501 (1994)
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[Publications] Mishima,K.,Ohno,S.,Shitara,N.,Yamaoka,K.,Suzuki,K.: "Opposite effects of the overexpression of protein kinase Cγ and δ on the growth properties of human glioma cell line U251 MG." Biochem.Biophys.Res.Commun.201. 363-372 (1994)
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[Publications] Hirai,S-I.,Izumi,Y.,Higa,K.,Mizuno,K.,Osada,S.,Kaibuchi,K.,Suzuki,K.,Ohno,S: "Ras-dependent signal transduction is indispensable but not sufficient for the activation of APl/Jun by PKCδ." EMBO J.13. 2331-2340 (1994)
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[Publications] Akimoto,K.,Mizuno,K.,Osada,S.,Hirai,S-I.,Tanuma,S.,Suzuki,K.,Ohno,S.: "A new member of the third class of the protein kinase C family,PKCλ,ubiquitously expressed dominantly in an undifferentiated mouse embryonal carcinoma cell line and also in many tissues and cells." J.Biol.Chem.269. 12677-12683 (1994)
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[Publications] Chida,R.,Sagara,H.,Suzuki,Y.,Murakami,A.,Osada,S.,Ohno,S.,Hirosawa,K.,Kuroki,T.: "THE η isoform of protein kinase C is localized on rough endoplasmicreticulum." Mol.Cell.Biol.114. 3782-3790 (1994)
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[Publications] Koyama,H.,Inaba,M.,Nishizawa,Y.,Ohno,S.,Morii,H.: "Protein kinase C is involved in 24-hydroxylase gene expression induced by 1,25(OH)_2D_3 in rat intestinal epithelial cells" J.Cellular Biol.14. 3782-3790 (1994)
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[Publications] Akita,Y.,Ohno,S.,Yajima,Y.,Konno,Y.,Saido,T.C.,Mizuno,K.,Chida,K.,Osada,S.,Kuroki,T.: "Overproduction of a Ca^<2+>-independent protein kinase C isozyme,nPKCε,increases the secretion of prolactin from thyrotropin-releasing hormone-stimulated rat pituitary GH4C1 cells." J.Biol.Chem.269. 4653-4660 (1994)
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[Publications] Kamada,S.,Toyoshima,K.,Akiyama,T.: "Serum-independent phosphorylation of c-Jun and alteration of AP-1 components by transformation with various oncogenes." J.Biol.Chem.269. 4565-4570 (1994)
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[Publications] Inoue,K.,Sugiyama,H.,Ogawa,H.,Nakagawa,M.,Yamagami,T.,Miwa,H.,Kita,K.,Hiraoka,A.,Masaoka,T.,Naru,K.,Kyo,Y.,Dohy,H.,Nakauchi,H.,Ishidate,T.,Akiyama,T.,Kishimoto,T.: "WT1 as a new prognostic factor and a new marker for the detection of minimal residual disease in acute leukemia." Blood. 84. 3071-3097 (1994)
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[Publications] Kudoh,T.,Ishidate,T.,Moriyama,M.,Toyoshima,K.,Akiyama,T.: "G1 phase arrest induced by Wilms tumor protein WT1 is abrogated by cyclin/CDK" Proc,Natl.Acad.Sci.USA. (in press). (1995)
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[Publications] Fukuda,K.,Saito,N.,Yamamoto,M.,Tanaka,C.: "Immunocytochemical localization of α-,βI-,βII-and γ-subspecies of protein kinase C in the monkey visual pathway." Brain Res.958. 155-162 (1994)
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[Publications] Ikegaki,N.,Saito,N.,Hasima,M.,Tanaka,C.: "Production of specific antibodies against GABA transporter subtypes(GAT1,GAT2,GAT3)and their application to immunocytochemistry." Mol.Brain Res.26. 47-54 (1994)
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[Publications] Yamamura,H.: "Syk Spleen tyrosine kinase(vertebrates).In The Protein Kinase Factsbook(edited by Hardie,G.,Hanks,S.)" Academic Press Limited,(in press), (1995)
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[Publications] Ohno,S.,Suzuki,K.: "YKR2 PK(S.cerevisiae).In The Protein Kinase Factsbook(edited by Hardie,G.,Hanks,S.)" Academic Press Limited,(in press), (1995)
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[Publications] Ohno,S.,Suzuki,K.: "Protein kinase C(vertebrates)Ca^<2+>-& phospholipid-dependent protein kinase.In The Protein Kinase Factsbook(edited by Hardie,G.,Hanks,S.)" Academic Press Limited,(in press), (1995)
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[Publications] Suzuki,K.,Akita,Y.,Ohno,S.: "Structural and functional diversities of protein kinase C family members.In Recent Advances in Molecular and Biochemical Research on Proteins(edited by Wei,Y.-H.,Chen,C.-S.,Su,J.-C.)" World Scientific Pub.Co., 157-166 (1994)
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[Publications] Kanaide,H.: "The cytosolic calcium-force relation of vascular smooth muscle during the contraction and the relaxation.InPathophysiology of Heart Failure(edited by Dhalla,N.S.,Singal,P.K.,Takeda,N.,Beamish R.E.)" Kluwer Academic Publisher,Boston,(in press), (1995)
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[Publications] Kanaide,H.: "The〔Ca^<2+>〕i-force relationship in vascular smooth muscle.In Regulation of the Contractile Cycle in Smooth Muscle(edited by Nakano,T.)" Springer-Verlag,Tokyo,(in press), (1995)