1996 Fiscal Year Annual Research Report

中枢神経系のベーシック・デザインに関する比較研究

Research Project

Project/Area Number	07304056
Research Institution	Okayama University
Principal Investigator	山口恒夫岡山大学, 理学部, 教授 (60000816)
Co-Investigator(Kenkyū-buntansha)	小泉修福岡女子大学, 人間環境学部, 教授 (50094777) 冨永佳也福岡大学, 理学部, 教授 (70078591) 宗岡洋二郎広島大学, 総合科学部, 教授 (40031330) 桑沢清明東京都立大学, 理学部, 教授 (10015589) 水波誠北海道大学, 電子科学研究所, 助教授 (30174030)
Keywords	中枢神経系 / 脳 / 基本設計 / 比較研究 / 動物の多様性
Research Abstract	各分担者によって得られた成果を要約すると,次のようになる.(1)ザリガニ脳内のノンスパイキング巨大介在ニューロンの応答性と眼柄の補償運動を解析し,脳の動作原理にニューロンの冗長性が大きく係わっていることを確認した(山口).(2)昆虫のキノコ体が,哺乳類の大脳皮質などと類似したモジュール構造をもつことを明らかにした(水波).(3)カイコガの脳内で,フリップ・フロップ回路的な動作を示すニューロン回路で運動パターンが形成され,性フェロモンに対する定位行動を発現することを見い出した(神崎).(4)ウズラの脳における歌発生機能部位が中脳内側部であることを確認し,歌発生に対するテストステロンが歌パターンを切り替えることなどを見い出した(青木).(5)ウミフクロを用いて,セロトニ作動性ニューロン,ヒスタミン作動性ニューロンなどの神経系築を明かにした(桑沢).(6)魚類嗅球の僧帽細胞と顆粒細胞間のシナプスで,長期増強現象を見い出した(佐藤).(7)棘胞動物,棘皮動物,環形動物,軟体動物,節足動物,脊椎動物などから約80種類の新規生理活性ペプチドを同定した(宗岡).(8)カエル視蓋ニューロンのシナプス電位と視神経の電気刺激によるフィールドの電位の解析を行い,シナプス電位の時空間受容野,視蓋の細胞構築と深さ方向の情報の流れの関係をなどを明かにした(松本).(9)各種昆虫の脳構造の比較,学習行動などについて解析し,これらが昆虫の生活様式に適応していることを見い出した(藤).(10)ゲンジボタルの脳に投射する6種類の感覚子を精査するとともに,種々の方法でワモンゴキブリのキノコ体を調べ,キノコ体が階層的に機能単位が並列する構造であることを明かにした(冨永).(11)ヒドラの神経環の機能を調べ,神経環が摂食反応の発現に必須ではなく,より高次な機能に関係していることなどを明らかにした(小泉).

Research Products

(41 results)

All Other

All Publications (41 results)

[Publications] Furudate,H.,Okada,Y.and Yamaguchi,T.: "Responses of non-spiking giant interneurons to substrate tilt in the crayfish,with special reference to multisensory control in the compensatory eyestalk movement system." J.Comp.Physiol.A. 179. 635-643 (1996)
[Publications] Mizunami,M.: "Gain control of synaptic transfer from second-to third-order neurons of cockroach ocelli." J.Gen.Physiol.107. 121-131 (1996)
[Publications] 水波誠: "明暗視から運動視への進化と基本設計" BME. 10. 38-47 (1996)
[Publications] Kanzaki,R.: "Behavioral and neural basis of instinctive behavior ininsects : Odor-source searching strategies without memory and learning." Robotics and Autonomus Systems. 18. 33-43 (1996)
[Publications] Ariyosi,T.and Kanzaki,R.: "Pheromone-triggered Electromyograms of flight muscles in a male silkworm moth,Bombyx mori." Int.Wilmoth & Silk. 2. 21-25 (1996)
[Publications] Ishida H.et.al.: "Odor-source localization system mimicking behavior of silkworm moth." Sensors and Actuators A. 51. 225-230 (1996)
[Publications] Okada,K.,Kanzaki,R.and Kawachi,K.: "High-speed voltage-sensitive dye imaging of an in vivo insect brain." Neurosci.Lett.209. 1-4 (1996)
[Publications] 神崎亮平: "フェロモン源へのフリップ・フロップ航法" 医用電子と生体工学. 10(11). 11-18 (1996)
[Publications] 神崎亮平: "嗅覚の神経生理学激研究-昆虫の嗅覚系の研究を主として-" 日本味と匂学会誌. (印刷中). (1997)
[Publications] Yazaki,Y.,Matsusima,T.and Aoki,K.: "Testosterone modulates calling behavior in Japanese quail chicks." Zool.Sci.14(2) (in press). (1997)
[Publications] Yazaki,Y.,Matsusima,T.and Aoki,K.: "Stimulation elicits the chick crowing with testosterone in Japanese quail chicks." Zool.Sci.14(2) (in press). (1997)
[Publications] Matsumura,S.and Kuwasawa,K.: "Both the heart and pericardium in the chiton Acanthopleura japonica receive dual innervation from the central nervous system." Zool.Sci.13. 55-62 (1996)
[Publications] 桑沢清明・矢沢徹: "単一細胞レベルでの神経性産津学-甲殻類をモデルとした心拍と血流制御の神経機構-" 遺伝. 別冊No.8. 70-79 (1996)
[Publications] Satou,M.,Kudo,Y.and Kitamura,S.: "Strategies for studying the olfactory mechanism i salmon homing." Bull.Natl.Res.Inst.Aquacult.Suppl.2. 49-57 (1996)
[Publications] Ukena,K.et al.: "Inhibitory pentapeptides isolated from the gut of the earth worm,Eisenia foetida." Comp.Biochem.Physiol.114A. 245-249 (1996)
[Publications] Li,D.et al.: "An oviposition-inducing peptide : isolation,Iocalization,and function of avian galanin in the quail oviduct." Endocrinology. 137. 1618-1626 (1996)
[Publications] Tsutsui,K.et al.: "Demonstration,Icoalization and development of galanin receptors in the quail oviduct." J.Exp.Zool.(in press). (1997)
[Publications] 藤本正昭他: "インドヒラマキガイからの生理活性ペプチドの単離" 島根大学生物資源学部紀要. (in press). (1997)
[Publications] Ohtani,M.at al.: "Isolation of bloactive compounds from Helix aspersa nerve tissue and the effect of pQPPLPRY. amide on heart,oesophagus and central neurons of H. asoersa and rectum of Anodonta woodiana." J.Gen.Pharmacol.(in press). (1997)
[Publications] Chiba,C.et al.: "Time course of appearance of GABA and GABA-receptors during retinal regeneration in the adult newt." Brain Res.(in press). (1997)
[Publications] Takahashi,T.et al.: "Systematic isolation of peptide gignal molecules from Hydra. 1.Strategy for isolation and characterization of the LW amide and PW families." Proc.Natl.Acad.Sci.USA. (in press). (1997)
[Publications] Matsumoto,N.,Sadamori,E.and Sugihara,T.: "Rise time and amplitude of visually elicited EPSPs of tectal neurons of the frog." Acta Biologica Hungarica. 47. 303-312 (1996)
[Publications] Nakagawa,H.,Miyazaki,H.and Matsumoto,N.: "Principal neuronal organization in the frog optic tectum revealed by a current source density analysis" Visual Neurosci.(in press).
[Publications] Mizutani,A.and Toh,Y.: "Behavioral analysis of distinct visual responses of the tigerbeetle (Cicindela chinensis) larva." J.Comp.Physiol.(in press).
[Publications] Murate,M.et al.: "Scannning electron microscopy of endodermal sensory cells of Hydra magnipapillata." Cell Tissue Res.283. 455-459 (1996)
[Publications] 小泉修: "ヒドラの再生" 遺伝. 50(4). 38-44 (1996)
[Publications] 水波誠: "昆虫の記憶と学習青木清編「行動生物学」" 朝倉書店, 2 (1996)
[Publications] 神崎亮平: "「図解行動生物学」青木清編" 朝倉書店(印刷中), (1997)
[Publications] Kanzaki,R.: "Pheromone processng in the lateral accessory lobes of the moth brain : flipflopping signals related to zigzagging upwind walking. "Pheromone research : new directions" (Eds.R.T.Carde & A.K.Minks)" Chapman and Hall (in press), (1996)
[Publications] Tanaka,K.et al.: "Neuronal control of cardiac output in the isopod crustacean,Bathynomus doederleini. In : H.Koike et al. (ed.) Basic Neuroscience in Invertebrates." Business Center for Academic Societies, 14 (1996)
[Publications] 佐藤真彦: "生物科学入門コース第6巻「脳・神経と行動」" 岩波書店, (1996)
[Publications] Minakata,H.et al.: "A new peptide containing a D-amino acid from the snail,Helix pomatia-roles of D-amino acid residue-,Peptide Chemistry 1995 Ed. by Nishi,N." Protein Research Foundation, 4 (1996)
[Publications] Teranishi,H.et al.: "Structre and action of bioactive peptides isolated from the newt,Cynopspyrrhogaster -I.a C-type natriuretic peptide (CNP). Peptide Chemistry 1995 Ed. Nishi,N." Protein Research Foundation, 4 (1996)
[Publications] Teranishi,H.et al.: "Structure and action of bioactive peptides isolated from the newt,Cynops pyrrhogaster-II. four VIP-related peptides and two neurotensin-related peptides.,Peptide Chemistry 1995 Ed. by Nishi,N." Protein Research Fondation, 4 (1996)
[Publications] Ohtani,M.et al.: "Isolation of neurotensin-related bioactive pentapeptides from peptide libraries synthesized with a multipeptide synthesizer. Peptide Chemistry 1995 Ed. by Nishi,N." Protein Research Foundation, 4 (1996)
[Publications] Kinjo,S.et al.: "Bioactive peptides isolated from an Afrocan ancient-type fish,Polypterus senegalus. Peptide Chemistry 1995 Ed. by Nishi,N." Protein Research Foundation, 4 (1996)
[Publications] Ikeda,T.et al.: "RGWamide,an APGWamide-related neuropeptide from anechiuroid worm,Urechis unicinctus. Peptide Chemistry 1995 Ed. by Nishi,N." Protein Research Foundation, 4 (1996)
[Publications] Ohtani,M.et al.: "Isolation of bioactive peptides from Wamide-peptide libraries synthesized with a multipeptide synthesizer. Peptide Chemistry 1996 Ed. by Kitada,C." Protein Research Foundation (in press), (1997)
[Publications] Ohtani,M.et al.: "pQVPLPRYamide isolated from the clam Meretrix lusoria : a member of a novel molluscan neuropeptide family. Peptide Chemistry 1996 Ed. by Kitada,C." Protein Research Foundation (in press), (1997)
[Publications] Takahashi,T.et al.: "Structure-activity relation of LWamide peptides synthesized with a multipeptide synthesizer. Peptide Chemistry 1996 Ed. by Kitada,C." Protein Research Foundation (in press), (1997)
[Publications] 小早川義尚・小泉修: "腔腸動物の組織不適合性と細胞性防御和合治久編「動物の血球細胞と生体防御」" 菜根出版(印刷中), (1997)

1996 Fiscal Year Annual Research Report

中枢神経系のベーシック・デザインに関する比較研究

Principal Investigator

山口 恒夫 岡山大学, 理学部, 教授 (60000816)

Research Products

[Publications] Furudate,H.,Okada,Y.and Yamaguchi,T.: "Responses of non-spiking giant interneurons to substrate tilt in the crayfish,with special reference to multisensory control in the compensatory eyestalk movement system." J.Comp.Physiol.A. 179. 635-643 (1996)

[Publications] Mizunami,M.: "Gain control of synaptic transfer from second-to third-order neurons of cockroach ocelli." J.Gen.Physiol.107. 121-131 (1996)

[Publications] 水波 誠: "明暗視から運動視への進化と基本設計" BME. 10. 38-47 (1996)

[Publications] Kanzaki,R.: "Behavioral and neural basis of instinctive behavior ininsects : Odor-source searching strategies without memory and learning." Robotics and Autonomus Systems. 18. 33-43 (1996)

[Publications] Ariyosi,T.and Kanzaki,R.: "Pheromone-triggered Electromyograms of flight muscles in a male silkworm moth,Bombyx mori." Int.Wilmoth & Silk. 2. 21-25 (1996)

[Publications] Ishida H.et.al.: "Odor-source localization system mimicking behavior of silkworm moth." Sensors and Actuators A. 51. 225-230 (1996)

[Publications] Okada,K.,Kanzaki,R.and Kawachi,K.: "High-speed voltage-sensitive dye imaging of an in vivo insect brain." Neurosci.Lett.209. 1-4 (1996)

[Publications] 神崎亮平: "フェロモン源へのフリップ・フロップ航法" 医用電子と生体工学. 10(11). 11-18 (1996)

[Publications] 神崎亮平: "嗅覚の神経生理学激研究-昆虫の嗅覚系の研究を主として-" 日本味と匂学会誌. (印刷中). (1997)

[Publications] Yazaki,Y.,Matsusima,T.and Aoki,K.: "Testosterone modulates calling behavior in Japanese quail chicks." Zool.Sci.14(2) (in press). (1997)

[Publications] Yazaki,Y.,Matsusima,T.and Aoki,K.: "Stimulation elicits the chick crowing with testosterone in Japanese quail chicks." Zool.Sci.14(2) (in press). (1997)

[Publications] Matsumura,S.and Kuwasawa,K.: "Both the heart and pericardium in the chiton Acanthopleura japonica receive dual innervation from the central nervous system." Zool.Sci.13. 55-62 (1996)

[Publications] 桑沢清明・矢沢 徹: "単一細胞レベルでの神経性産津学-甲殻類をモデルとした心拍と血流制御の神経機構-" 遺伝. 別冊No.8. 70-79 (1996)

[Publications] Satou,M.,Kudo,Y.and Kitamura,S.: "Strategies for studying the olfactory mechanism i salmon homing." Bull.Natl.Res.Inst.Aquacult.Suppl.2. 49-57 (1996)

[Publications] Ukena,K.et al.: "Inhibitory pentapeptides isolated from the gut of the earth worm,Eisenia foetida." Comp.Biochem.Physiol.114A. 245-249 (1996)

[Publications] Li,D.et al.: "An oviposition-inducing peptide : isolation,Iocalization,and function of avian galanin in the quail oviduct." Endocrinology. 137. 1618-1626 (1996)

[Publications] Tsutsui,K.et al.: "Demonstration,Icoalization and development of galanin receptors in the quail oviduct." J.Exp.Zool.(in press). (1997)

[Publications] 藤本正昭 他: "インドヒラマキガイからの生理活性ペプチドの単離" 島根大学生物資源学部紀要. (in press). (1997)

[Publications] Ohtani,M.at al.: "Isolation of bloactive compounds from Helix aspersa nerve tissue and the effect of pQPPLPRY. amide on heart,oesophagus and central neurons of H. asoersa and rectum of Anodonta woodiana." J.Gen.Pharmacol.(in press). (1997)

[Publications] Chiba,C.et al.: "Time course of appearance of GABA and GABA-receptors during retinal regeneration in the adult newt." Brain Res.(in press). (1997)

[Publications] Takahashi,T.et al.: "Systematic isolation of peptide gignal molecules from Hydra. 1.Strategy for isolation and characterization of the LW amide and PW families." Proc.Natl.Acad.Sci.USA. (in press). (1997)

[Publications] Matsumoto,N.,Sadamori,E.and Sugihara,T.: "Rise time and amplitude of visually elicited EPSPs of tectal neurons of the frog." Acta Biologica Hungarica. 47. 303-312 (1996)

[Publications] Nakagawa,H.,Miyazaki,H.and Matsumoto,N.: "Principal neuronal organization in the frog optic tectum revealed by a current source density analysis" Visual Neurosci.(in press).

[Publications] Mizutani,A.and Toh,Y.: "Behavioral analysis of distinct visual responses of the tigerbeetle (Cicindela chinensis) larva." J.Comp.Physiol.(in press).

[Publications] Murate,M.et al.: "Scannning electron microscopy of endodermal sensory cells of Hydra magnipapillata." Cell Tissue Res.283. 455-459 (1996)

[Publications] 小泉 修: "ヒドラの再生" 遺伝. 50(4). 38-44 (1996)

[Publications] 水波 誠: "昆虫の記憶と学習 青木清編「行動生物学」" 朝倉書店, 2 (1996)

[Publications] 神崎亮平: "「図解行動生物学」 青木清編" 朝倉書店(印刷中), (1997)

[Publications] Kanzaki,R.: "Pheromone processng in the lateral accessory lobes of the moth brain : flipflopping signals related to zigzagging upwind walking. "Pheromone research : new directions" (Eds.R.T.Carde & A.K.Minks)" Chapman and Hall (in press), (1996)

[Publications] Tanaka,K.et al.: "Neuronal control of cardiac output in the isopod crustacean,Bathynomus doederleini. In : H.Koike et al. (ed.) Basic Neuroscience in Invertebrates." Business Center for Academic Societies, 14 (1996)

[Publications] 佐藤真彦: "生物科学入門コース第6巻「脳・神経と行動」" 岩波書店, (1996)

[Publications] Minakata,H.et al.: "A new peptide containing a D-amino acid from the snail,Helix pomatia-roles of D-amino acid residue-,Peptide Chemistry 1995 Ed. by Nishi,N." Protein Research Foundation, 4 (1996)

[Publications] Teranishi,H.et al.: "Structre and action of bioactive peptides isolated from the newt,Cynopspyrrhogaster -I.a C-type natriuretic peptide (CNP). Peptide Chemistry 1995 Ed. Nishi,N." Protein Research Foundation, 4 (1996)

[Publications] Teranishi,H.et al.: "Structure and action of bioactive peptides isolated from the newt,Cynops pyrrhogaster-II. four VIP-related peptides and two neurotensin-related peptides.,Peptide Chemistry 1995 Ed. by Nishi,N." Protein Research Fondation, 4 (1996)

[Publications] Ohtani,M.et al.: "Isolation of neurotensin-related bioactive pentapeptides from peptide libraries synthesized with a multipeptide synthesizer. Peptide Chemistry 1995 Ed. by Nishi,N." Protein Research Foundation, 4 (1996)

[Publications] Kinjo,S.et al.: "Bioactive peptides isolated from an Afrocan ancient-type fish,Polypterus senegalus. Peptide Chemistry 1995 Ed. by Nishi,N." Protein Research Foundation, 4 (1996)

[Publications] Ikeda,T.et al.: "RGWamide,an APGWamide-related neuropeptide from anechiuroid worm,Urechis unicinctus. Peptide Chemistry 1995 Ed. by Nishi,N." Protein Research Foundation, 4 (1996)

[Publications] Ohtani,M.et al.: "Isolation of bioactive peptides from Wamide-peptide libraries synthesized with a multipeptide synthesizer. Peptide Chemistry 1996 Ed. by Kitada,C." Protein Research Foundation (in press), (1997)

[Publications] Ohtani,M.et al.: "pQVPLPRYamide isolated from the clam Meretrix lusoria : a member of a novel molluscan neuropeptide family. Peptide Chemistry 1996 Ed. by Kitada,C." Protein Research Foundation (in press), (1997)

[Publications] Takahashi,T.et al.: "Structure-activity relation of LWamide peptides synthesized with a multipeptide synthesizer. Peptide Chemistry 1996 Ed. by Kitada,C." Protein Research Foundation (in press), (1997)

[Publications] 小早川義尚・小泉 修: "腔腸動物の組織不適合性と細胞性防御 和合治久編「動物の血球細胞と生体防御」" 菜根出版(印刷中), (1997)

山口恒夫岡山大学, 理学部, 教授 (60000816)

[Publications] 水波誠: "明暗視から運動視への進化と基本設計" BME. 10. 38-47 (1996)

[Publications] 桑沢清明・矢沢徹: "単一細胞レベルでの神経性産津学-甲殻類をモデルとした心拍と血流制御の神経機構-" 遺伝. 別冊No.8. 70-79 (1996)

[Publications] 藤本正昭他: "インドヒラマキガイからの生理活性ペプチドの単離" 島根大学生物資源学部紀要. (in press). (1997)

[Publications] 小泉修: "ヒドラの再生" 遺伝. 50(4). 38-44 (1996)

[Publications] 水波誠: "昆虫の記憶と学習青木清編「行動生物学」" 朝倉書店, 2 (1996)

[Publications] 神崎亮平: "「図解行動生物学」青木清編" 朝倉書店(印刷中), (1997)

[Publications] 小早川義尚・小泉修: "腔腸動物の組織不適合性と細胞性防御和合治久編「動物の血球細胞と生体防御」" 菜根出版(印刷中), (1997)