• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to project page

1996 Fiscal Year Final Research Report Summary

Non-invasive measurement of tissue oxygenation using near-infrared spectroscopy

Research Project

Project/Area Number 07457247
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field General surgery
Research InstitutionUNIVERSITY OF TOKYO

Principal Investigator

SHIGEMATSU Hiroshi  University of Tokyo, Surgery, Assistant Professor, 医学部・附属病院, 助教授 (40134556)

Co-Investigator(Kenkyū-buntansha) HOSOI Yutaka  University of Tokyo, Surgery, Assistant, 医学部・附属病院, 医員
KOMIYAMA Takashi  University of Tokyo, Surgery, Assistant, 医学部・附属病院, 助手
ARAMOTO Haruo  University of Tokyo, Surgery, Assistant, 医学部・附属病院, 助手
ONO Masaya  University of Tokyo, Surgery, Assistant, 医学部・附属病院, 助手
YASUHARA Hiroshi  University of Tokyo, Surgery, Lecturer, 医学部・附属病院, 講師 (50251252)
Project Period (FY) 1995 – 1996
Keywordsnear-infrared spectroscopy / tissue oxygenation / ischemia / venous insufficiency
Research Abstract

We measured tissue oxygenation in the calf muscle during exercise using near-infrared spectroscopy.
The reproducibility and the accuracy of this method were as same as of the Doppler method in pressure measurement.
Between three different algorithms, The Formula of Tamura was an adequate algorithm for the measurement of muscle oxygenation during exercise.
In clinically, this method made it possible to assess the severity of muscle ischemia and muscle congestion in the patients suffering with peripheral arterial obstruction and with venous insufficiency.
In the experimental models using New Zealand White rabbits, it was possible to assess the recovery of the oxygenation in the calf muscle after hindlimb ischemia caused by the ligation of the femoral artery.
The anti-platelet agent improved the muscle oxygenation after ischemia using this model.

  • Research Products

    (20 results)

All Other

All Publications (20 results)

  • [Publications] 小見山 高士: "下肢閉塞性動脈硬化症に対する薬効判定-近赤外分光法による客観的薬効評価法-" 脈管学. 35(3). 181-187 (1995)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 細井 温: "近赤外線分光法を用いた間歇性跛行肢の筋肉内酸素動態評価法" Therapeutic Research. 16(9). 3107-3109 (1995)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 重松 宏: "慢性動脈閉塞症の診断と治療" 日本医師会雑誌. 115(3). 317-323 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 重松 宏: "末梢動脈疾患の無侵襲診断" Therapeutic Research. 17(7). 2522-2527 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 重松 宏: "血行動態検査" 日本外科学会雑誌. 97(7). 510-514 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 細井 温: "近赤外線分光法を用いた歩行運動中下肢静脈還流障害の評価" 静脈学. 7(4). 381-386 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 小見山 高士: "近赤外分光法を用いた虚血臓器組織酸素代謝の評価について-全波長型分光法装置による組織酸素飽和度測定-" Therapeutic Research. 35(3). 181-187 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 重松 宏: "閉塞性動脈硬化症の治療方針" 臨床医. 22(11). 2514-2516 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Takashi Komiyama: "An objective evaluation of muscle oxygen content in claudicants receiving drug therapy" International Angiology. 15(3). 215-218 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Yutaka Hosoi: "A new method for the assessment of venous insufficiency in primary varicose veins using near-infrared spectroscopy" Journal of Vascular Surgery. 26(1). 53-60 (1997)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Komiyama T.: "An objective evaluation of muscle oxygen content in claudicants on drugs" Myakkan-gaku. 35(3). 181-187 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Hosoi Y.: "An objective assesment of changes in muscle oxygenation for claudicants by near-infrared spectroscopy" Therapeutic Research. 16(9). 3106-3109 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Shigematsu H.: "Diagnosis and therapy for chronic arterial occlusive diseases" Nihon Ishikai Zasshi. 115(3). 317-323 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Shigematsu H.: "Non-invasive diagnosis for peripheral vascular diseases" Thrapeutic Research. 97(7). 2522-2527 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Shigematsu H.: "Hemodynamic study for the assessment of atherosclerotic occlusive disease" Journal of Japanese Surgical Society. 97(7). 510-514 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Hosoi Y.: "The assessment of ambulatory venous function in patients with chronic venous insufficiency" Japanese Journal of Phlebology. 7(4). 381-386 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Komiyama T.: "An objective evaluation for tissue oxygenation" Therapeutic Research. 35(3). 181-187 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Shigematsu H.: "Strategy for aterosclerotic obliterans" Rinsho-I. 22(11). 2514-2516 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Komiyama T.: "An objective evaluation of muscle oxygen content in claudicants receiving drug therapy" International Angiology. 15(3). 215-218 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Hosoi Y.: "A new method for the assessment of venous insufficiency in primary varicose veins using near-infrared spectroscopy" Journal of Vascular Surgery. 26(1). 53-60 (1997)

    • Description
      「研究成果報告書概要(欧文)」より

URL: 

Published: 1999-03-16  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi