1996 Fiscal Year Final Research Report Summary
Preparation of chemically bonded anatite for biomaterials
| Project/Area Number |
07555275
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 試験 |
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| Research Field |
無機工業化学
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| Research Institution | TOKYO METROPOLITAN UNIVERSITY |
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Principal Investigator |
UMEGAKI Takao Tokyo Met. Univ. , Eng. Prof., 工学部, 教授 (70087287)
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| Co-Investigator(Kenkyū-buntansha) |
HAMAGAMI Junichi Tokyo Met. Univ. , Eng. Res. Assoc., 工学部, 助手 (30285100)
SUDA Seiichi Tokyo Met. Univ. , Eng. Res. Assoc., 工学部, 助手 (50226578)
MATSUDA Motohide Okayama Univ. , Environment, Sci. & Eng. Assoc. Prof., 環境理工学部, 助教授 (80222305)
YAMASHITA Kimihiro Tokyo Met. Univ. , Eng. Assoc. Prof., 工学部, 助教授 (70174670)
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| Project Period (FY) |
1995 – 1996
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| Keywords | biomaterials / apatite / hydraulic hardening / chemically bouded ceramics / water-soluble polymer |
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| Research Abstract |
Preparation of hydraulic hardened bodies of calcium phosphates was carried out adding polyacrylamide, polymethylmetacrylate, monomer of acrylamide. Hydrolysis of calcium phosphates were remarkably retarded by the above additives at room temparature and accelerated 80ﾟC.Thermal decomposition products of hydroxyapatite, alpha-Ca_3 (PO_4)_2, beta-Ca_3 (PO_4)_2 and amorphous calcium phosphate were used as calcium phosphate cements.
Acrylamide monomer in the thermal decomposition products of apatite was polimerized at first and then the calcium phosphate cements were heated in water. The calcium phosphate hardened bodies thus obtained were found to be about 1.7 in bulkdensity and 11-12 MP a in bending strength, which was doubled compared with that obtained on no addition of polymers. In addition to the above hydration conditions, bridging agents for acrylamide monomer was used on the preparation of hydraulic calcium phosphates. The calcium phosphate bodies containing the bridging agent were found to be about 1.8 in bulk density and about 20 MPa in bending strength. Silica addition into calcium phosphate cements improved the workability of the cement slurries.
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