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1997 Fiscal Year Final Research Report Summary

Research for developing a practical system to test non-cariogenic foods and sugar substitutes

Research Project

Project/Area Number 07557116
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section展開研究
Research Field Functional basic dentistry
Research InstitutionTOHOKU UNIVERSITY

Principal Investigator

YAMADA Tadashi  Tohoku Univ.Sch.of Dent.Professor, 歯学部, 教授 (50005021)

Co-Investigator(Kenkyū-buntansha) ABBE Kazuhiko  Tohoku Univ.Sch.of Dent.Associate Professor, 歯学部, 助教授 (40151089)
TAMAZAWA Yoshinori  Tohoku Univ.Dent.Hosp.Lecturer, 歯学部附属病院, 講師 (10124603)
WATANABE Makoto  Tohoku Univ.Sch.of Dent.Professor, 歯学部, 教授 (80091768)
Project Period (FY) 1995 – 1997
KeywordsFoods / Dental-caries / Indwelling-electrode / Sugar-substitutes / pH-in-plaque / Cariogenicity / Saliva / Medicine
Research Abstract

We developed the practical system to measure the in vivo interdental plaque-pH of low molar teeth in humans using an indewelling electrode. Our methods and data were compared with those of three test laboratories authorized by Toothfriendly Sweets International. After a careful investigation our research group is approved and registered as the fourth test laboratory. Several foods and oral medicines were tested practically by our indwelling system. Most of throat lozenges and cough-and-cold medicated syrups availabe in Japan turned out to be acidogenic. Their fermentative sugars should be substituted by non-or low-acidogenic sweetners to reduce their cariogenic potential. Our research work is expected to provide social profits in cooperation with suitable confectionery and pharmaceutical companies. The importance of salivary role was practically demonstrated in keeping in vivo plaque-pH high. It is important to think about what to eat, how to eat and when to eat in order to prevent dental caries practically. This research work makes possible to present concrete information on acidogenicity of foods when and how they are taken. The careful consideration of eating habits in preventing dental caries are made an appeal not only to the professional field but also to the general public through the mass media such as news papers etc.

  • Research Products

    (14 results)

All Other

All Publications (14 results)

  • [Publications] 張 平: "日本で市販されている口中錠の歯垢内酸産生せい-電極内臓法による歯垢pHの測定-" 東北大学歯学雑誌. 14. 75-81 (1995)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 阿部 一彦: "むし歯を予防する唾液の働き" 治療. 77(8). 124-125 (1995)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 尹 梅: "日本で市販されている小児用シロップ液状総合感冒剤の歯垢内酸産生性" 東北大学歯学雑誌. 15. 163-170 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 玉澤 佳純: "非う蝕誘発性の食品を検定するための実用的な歯垢pHの測定方法" 日本補綴歯科学会雑誌. 40. 147- (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Iwami, Y: "Mechanism of inhibition of acid production in Streptococcus mutans by sodiium ions under strictly amaerobic conditions." Oral Microbiol Immcen. 12. 178-182 (1997)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 阿部 一彦: "食品の齲蝕誘発性の評価-歯垢pH測定試験-" 歯界展望. 90. 650-654 (1997)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 阿部 一彦: "う蝕細胞の分子生物学(武笠英彦監修)" クィンテッセン出版, 16 (1997)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Zhang P.: "Acidogenic potential on human dental plaque pH of throat lozenges available in Japan-in vivo pH measurement by telemetry with indwelling microelectrode-." Tohoku Univ.Dent.J.14. 75-81 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Abbe K.: "Salivary role in preventing dental caries." J.Therap.77 (8). 124-125 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Yin M.: "Acidogenic potential of human dental plaque exposed to general cough and cold medicated syrups currently available in Japan." Tohoku Univ.Dent.J.15. 163-170 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Tamazawa Y.: "Development of practical method to select non-cariogenic foods and sugar substitutes." J.Jpn.Prosthodont.Soc.40 (Special Issue). 147 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Iwami Y.: "Mechanism of inhibition of acid production in Streptococcus mutans by sodium ions under strictly anaerobic conditions." Oral Microbiol Immun.12. 178-182 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Abbe K.: "Evaluation of the cariogenicity of foodstuffs-plaque acidogenicity tests-." Dental Outlook. 90 (3). 650-654 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Abbe K.: Glycolysis of Streptococcus mutans. (Molecular Biology of Cariogenic Bacteria (ed.Mukasa H.) ). Quintessence Book, 156-171 (1997)

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 1999-03-16  

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