1996 Fiscal Year Final Research Report Summary
Development of a new tissue conditioner possessed of an antibacterial/-fungal effect
| Project/Area Number |
07557273
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 試験 |
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| Research Field |
補綴理工系歯学
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| Research Institution | HIROSHIMA UNIVERSITY |
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Principal Investigator |
AKAGAWA Yasumasa Hiroshima Univ., Sch.of Dentistry, Professor, 歯学部, 教授 (00127599)
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| Co-Investigator(Kenkyū-buntansha) |
ABE Yasuhiko Hiroshima Univ., Sch.of Dentistry, Research Assistant, 歯学部, 助手 (00253097)
KUBO Takayasu Hiroshima Univ., Sch.of Dentistry, Research Assistant, 歯学部, 助手 (60240876)
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| Project Period (FY) |
1995 – 1996
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| Keywords | antimicrobial effect / tissue conditioner / silver-zeolite / dynamic viscoelastic property |
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| Research Abstract |
The purpose of the first study was to elucidate the in vitro antimicrobial effect of five commercially available tissue conditioners containing silverzeolite (2 wt%) on Candida albicans and nosocomial respiratory infectioncausing bacteria, Staphylococcus aureus and Pseudomonas aeruginosa. Tissue conditioners containing silver-zeolite have been shown to have antimicrobial effects for 4 weeks on C.albicans and nosocomial respiratory infection-causing bacteria in saliva in vitro.
The purpose of the second study was to evaluate dynamic viscoelastic properties of same five tissue conditioners containing silver-zeolite (0.2.5 and 10 wt%) using non-resonance forced vibration method. Measurements were carried out after without and with immersion in distillled water and artificial saliva at 37ﾟC for 24 hours, 1 week and 4 weeks. The results indicate that dynamic viscoelastic properties of tissue conditioners are influenced considerably by storage conditions and the time proceeds, and that there is a small effect of silver-zeolite.
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