1996 Fiscal Year Final Research Report Summary
Study on factors that transcriptionally regulate the gene encoding an immunodominant antigen expressed specifically in larval stage of Dirofilaria immitis.
| Project/Area Number |
07670274
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
寄生虫学(含医用動物学)
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| Research Institution | Shinshu University |
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Principal Investigator |
SUGANE Kazuo Shinshu University, School of Medicine, professor, 医学部, 教授 (50112488)
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| Co-Investigator(Kenkyū-buntansha) |
KATO Hisaharu Shinshu University, School of Medicine, assistant, 医学部, 助手 (40281042)
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| Project Period (FY) |
1995 – 1996
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| Keywords | Dirofilaria immitis / immunodominant antigen / promoter |
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| Research Abstract |
We characterized the genes (Dg2 and DgK) encoding an immunodominant antigen expressed specifically in larval stage of Dirofilaria immitis, and analyzed the function of promoter region of the gene. Microinjection study using Caenorhabditis elegans, the DgK might be expressed only in digestive tract of the nematode.
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