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1996 Fiscal Year Final Research Report Summary

Intracavitary hypethemo-radiotherapy for patients with carcinoma of esophagus

Research Project

Project/Area Number 07671036
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Radiation science
Research InstitutionKansai Medical University

Principal Investigator

HARIMA Keizou  Kansai Medical University Faculty of Medicine, Assistant Professor, 医学部, 助手 (20121973)

Co-Investigator(Kenkyū-buntansha) KAWA Soukichi  Kansai Medical University, Faculty of Medicine,, Assistant Professor, 医学部, 講師 (30152896)
AKAGI Kiyoshi  Kansai Medical University, Faculty of Medicine, Assistant Professor, 医学部, 講師 (30098115)
Project Period (FY) 1995 – 1996
Keywordsesphageal cancer / cavitary thermoradiation therapy / micro selectron
Research Abstract

In this study, We invesgated the effectiveness of intra cavitary thermoradiation therapy for local advanced esophageal cancer. (2 stage "II", 7 stage "III", 2 stage "IV") For selective irradiating of esophagus, micro selectron HDRIr-192 (Nucletron) was employed. Hyperthermia was administered to patients using aradiofrequency system with an endotract electrodes. A new endotract applicator, which a 6Fr. Radiation sourse tube was able to be inserted was used totreat for esophagial cancer. During intraluminal heat treatment of 30 min., brachytherapy was performed at a dose of 3.0-4.0Gy in fraction, and this treatment was performed 2 times/2 weeks. Intra cavitary thermoradiation therapy for esophageal canceris effective treatment. However, in patients who have been treated with intracavitary brachytherapy during heat treatment, this combination was not been getermined, the reasonable radiation dose, when is treated with intraluminal radiation therapy during hyperthemia, has to determine.

  • Research Products

    (6 results)

All Other

All Publications (6 results)

  • [Publications] Takuro Nishida,: Int.J.Hyperthemia. 13. 227-234 (1997)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Yoshizumi Aoki,: "Enhancement of thermal damage in murine tumors by hydralazine-induced modification of blood flow and oxygen tension"int.j.of Oncology. 11. 1123-1128 (1997)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Shigeki Ikeda,: "Enhancement of effect of an angiogenesis inhibitor on murine tumor by hyperhtermia."Oncology Report. 5. 181-183 (1998)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Takuro Nishida, Kiyoshi Akagi, Yoshimasa Tanaka: "Correlation between cell killing effect and cell membrane potential after heat treatment : analysis using fluorescent dye and flow cytometry"Int. J.Hyperthermia. Vol. 13. 227-234 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Yoshizumi Aoki, Hiroyoshi Isoda, Taichi Oshima, Kiyoshi Akagi, Toshiko Shiga, Reiko Nasu, Takashi Murata, Yoshimasa Tanaka: "Enhancement of thermal damage in murine tumors by hydralazine-induced modification of blood flow and oxygen tension"Int. J. of Oncology. Vol. 11. 1123-1128 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Shigeki Ikeda, Kiyoshi Akagi, Yoshimasa Tanaka: "Enhancement of effect of an angiogenesis inhibitor on murine tumor by hyperthermia"Oncology Report. Vol. 5. 181-184 (1998)

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 2001-10-23  

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