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1996 Fiscal Year Final Research Report Summary

ASSESSMENT OF HEART RATE VARIABILITY IN PATIENT UNDERGOING VASCULAR SURGERY

Research Project

Project/Area Number 07671653
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Anesthesiology/Resuscitation studies
Research InstitutionNAGOYA UNIVERSITY

Principal Investigator

KOMATSU Toru  NAGOYA UNIVERSITY SCHOOL OF MEDICINE ANESTHESIOLOGY ASSOCIATE PROFESSOR, 医学部, 助教授 (80109777)

Project Period (FY) 1995 – 1996
Keywordsheart rate variability / spectral analysis / nonlinear analysis / chaos / vascular surgery / autonomic nervous system / homeostasis / Surgical Stress
Research Abstract

The aim of this study was to examine whether simultaneous analysis of nonlinear and linear measures revealed different characteristics of heart rate variability (HRV) during perioperative period in patients undergoing vascular surgery. Low frequency, high frequency and total power of heart rate variability were decreased until 7th postoperative day as compared to control. The nonlinear measures changed immediate postoperative period, returning to control level within one week. Simultaneous analysis of nonlinear and linear measures of HRV revealed different patterns of alterations in status of dynamic cardiovascular homeostasis and autonomic nervous system after major vascular surgery. Using dimensional analysis, we heve shown that significant reduction occurred both the embedding and correlation of dimensions in HRV only during immediate postoperative period. Whereas, decreases in RR variance and all components of the spectral power of HRV persisted for one weak after major vascular surgery. Dimensional analysis revealed several distinct subcategories of patterns of alterations in HRV after major vascular surgery, which may correspond to different physiologic atates that are indistinguishable by simple atatistical analyzes, or the power spectrum of the time series of HRV.Non-linear and linear measures of HRV cannot be considered equivalent measures after major vascular surgery.

  • Research Products

    (12 results)

All Other

All Publications (12 results)

  • [Publications] 小松 徹: "生体情報の新しいモニタリング,心拍変動" 医学のあゆみ. 173. 1011-1015 (1995)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Komatsu.T: "Differential effects of ketamine and modozolain on heart rate variability" Can J Anesth. 42. 1003-1009 (1995)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 小松 徹: "麻酔薬の心拍変動におよぼす影響" 日臨麻誌. 15. 462-467 (1995)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 小松 徹: "集中治療患者とバイオシグナル" ICUとCCU. 20. 185-194 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 藤原 祥祐: "血管手術を受ける患者の術前評価法" 臨床麻酔. 20. 705-709 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 小松 徹: "手術侵襲と神経系" 麻酔. 45. S16-S24 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Komatsu T,Singh PK,Kimura T,Nishiwaki K,Bando K,Shimada Y: "Differential effects of ketamine and midazolam on heart rate variability" Can J Anaesth. 42. 1003-1009 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Komatsu T,Kimuar T,Shimada Y: "Biomedical time series analysis as a marker of autonomic nervous activity in critically ill patients" ICU & CCU. 20. 185-194

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Komatsu T,Kimura T: "Effects of Anesthetics on heart rate variability" Journal of Japanese clinical anesthesia. 15. 462-467 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Fujiwara Y et al: "Preoperative assessment of patients undergoing major vascular surgery" Clinical Anesthesia. 20. 705-709 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Komatsu T,Kimura T: "Surgical stress and autonomic nervous system" Masui. 45. S16-S24 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Kimura T,Komatsu T,Takezawa J,Shimada Y: "Alterations in spectral characteristics of heart rate variability as a correlate of cardiac autonomic dysfunction after esophagectomy or pulmonary resection" Anesthesiology. 84. 1068-1076 (1996)

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 1999-03-16  

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