1996 Fiscal Year Final Research Report Summary
Titanium Surface Modification with Ion Beam Mixing Method for Implant Use -Influence of Solubility of Thin Calcium-phosphate Coatings on Cell Behavior-
| Project/Area Number |
07672123
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
補綴理工系歯学
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| Research Institution | TOKYO DENTAL COLLEGE |
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Principal Investigator |
YOSHINARI Masao Tokyo Dental College, Department of Dentistry, Lecturer, 歯学部, 講師 (10085839)
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| Co-Investigator(Kenkyū-buntansha) |
INOUE Takashi Tokyo Dental College, Department of Dentistry, assistant professor, 歯学部, 助教授 (20125008)
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| Project Period (FY) |
1995 – 1996
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| Keywords | Implant / Coating / Calcium phosphate / Solubility / Crystallinity / Cell culture / Titanium / Hydroxyapatite |
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| Research Abstract |
In order to overcome a shortcoming of Ca-P coatings with the plasma spraying method, thin calcium-phosphate (Ca-P) coatings were produced by the ion beam dynamic mixing method which combined ion implantation and physical vapor deposition, resulting a thin, adherent and defect-free film. Thin coatings (approximately 1 mum) were coated onto titanium (Ti) substrates, followed by heat-treatment with conventional furnace heating and rapid heating of laser radiation and infrared radiation.
1. X-ray diffraction analysis revealed untreated films to be amorphous but to become crystalline after furnace heating at 500ﾟC and rapid heating with infrared radiation higher than 600ﾟC.
2. Solubility of coatings in simulated body fluid, adherence to Ti substrate, and X-ray photoelectron spectroscopy analysis at the interface between the coating and the Ti substrate were investigated. (1) Untreated films dissolved within 1 day. (2) Cracks were observed in coatings with furnace heating at 500ﾟC.X-ray photoelectron spectroscopy analysis at the interface between the coating and the Ti substrate showed that cracks were the result of decreased Ca-implanted layrs and too much growth of Ti-P compounds. (3) Coatings with laser radiation tended to dissolve easily with non-uniform surface degradation. (4) Infrared radiation controlled the Ca-P solubility and ensured the adherence of the coatings to the substrate. Coatings with infrared radiation at 600-700ﾟC dissolved minimally.
3. Cell culture test carried out with osteoblast-like cell using the rat bone marrow. SEM observation showed extracellular matrix formation on insoluble (crystallized) Ca-P coatings compared to on titanium surface and on soluble Ca-P coatings.
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