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[Publications] Hirano,M.,Osada,S.,Aoki,T.,Hirai,S.,Hosaka,M.,Inoue,J.,and Ohno,S.: "MEK kinase is involved in TNF α-mediated activation of NFkB and degradation of IkB α。" J.Biol.Chem.(in press).
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[Publications] Akimoto,K.,Takahashi,R.,Moriya,S.,Nishioka,N.,Takayanagi,J.,Kimura,K.,Fukui,Y.,Osada,S.,Mizuno,K.,Hirai,S.,Kazlauskas,A.,and Ohno,S.: "EGF and PDGF receptors activate atypical PKC λ through phosphatidylinositol 3-kinase." EMBO J.(in press).
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[Publications] Hirai,S.,Izawa,N.,Osada,S.,Spyrou,G.and Ohno,S.: "Activation of the JNK pathway by distantly related protein kinases,MEKK and MUK." Oncogene.12. 641-650 (1996)
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[Publications] Nishioka,N.,Hirai,S.,Mizuno,K.,Osada,S.,Suzuki,A.,Kosaka,K.,and Ohno,S.: "Wortmannin inhibits the activation of MAP kinase following Vasopressin V1 receptor stimulation." FEBS Lett.377. 393-398 (1995)
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[Publications] Wang,F.,Naik,U.P.,Ehrlich,Y.H.,Osada.S.,Ohno,S.and Komecki,E.: "Stimulatory antibody-induced activation and selective translocation of protein kinase C isoenzymes in human platelets." Biochem.J.311. 401-406 (1995)
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[Publications] Mizuno,K.Noda,K.,Ueda,Y.,Hanaki,H.,Saido,T-C.,Suzuki,K.,Ikuta,T.,Kuroki,T.,Tamaoki,T.,Hirai,S-I.,Osada,S.and Ohno,S.: "UCN-01,an anti-tumor drug,is a selective inhibitor of the conventional PKC subfamily." FEBS Lett.359. 259-261 (1995)
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[Publications] Hirano,M.,Hirai,S-I.,Mizuno,K.,Osada,S.,Hosaka,M.and Ohno,S.: "A protein kinase C isozyme,nPKCε,is involved in the activation of NF-к B by 12-0-tetradecanoylphorbol-13-acetate (TPA) in rat 3Y1 fibroblasts." Biochem.Biophys.Res Commun.206. 429-436 (1995)