1999 Fiscal Year Final Research Report Summary
Molecular approach for malaria control
| Project/Area Number |
08281102
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| Research Category |
Grant-in-Aid for Scientific Research on Priority Areas (A)
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| Allocation Type | Single-year Grants |
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| Research Institution | The University of Tokyo |
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Principal Investigator |
KITA Kiyoshi The University of Tokyo, Gladuate School of Medicine, Professor, 大学院・医学系研究科, 教授 (90134444)
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| Co-Investigator(Kenkyū-buntansha) |
KOJIMA Somei Institute of Medical Sciences, Professor, 医科学研究所, 教授 (00009622)
WATAYA Yusuke Okayama University, Graduate School of Pharmacy, Professor, 大学院・薬学研究科, 教授 (90127598)
HORII Toshihiro Oasaka University, Research Institute for microbial diseases, Professor, 微生物病研究所, 教授 (80142305)
AIKAWA Masamichi Tokai University, Research Institute of Medical Sciences, Professor, 総合科学技術研究所, 教授 (90271593)
TANABE Kazuyuki Osaka Institute of Technology, Faculty of Industy, Professor, 工学部, 教授 (40047410)
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| Project Period (FY) |
1996 – 2000
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| Keywords | Malaria / Tropical infectious diseases / Parasitic adaptation / vaccine / drug developmen / immunoresponse / animal model / vector |
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| Research Abstract |
Malaria is one of the important tropical diseases and many developing countries have been suffered from this re-emerging infectious disease. The main object of his research project is to establish a new approach for the control of malaria by studying molecular aspect of the parasite. Our general group has been organized to proceed an initial research plan properly. For this, we have established efficient research network among the members.
In addition, 2 meetings a year have been held from 1996 to 1999 to open our result to the public. Especially, the final meeting in 1999 has been organized as "Malaria Symposium". In this symposium, we invited Prof. Kishimoto who is the president of Osaka University, two foreign malaria researcher, Prof. Walliker and Prof. Cowman, to summarize and evaluate our result. Former Prime Minister, Mr. Hashimoto, also attended this Symposium as a guest and expressed his opinion about the importance of research on parasitic diseases and his desire to this research project.
By the accomplishment of this project, activity on the malaria research has been developed dramatically and distance to next step has been shortened. Namely, promising candidates of vaccines and drugs such as SERA protein and N-89, and a lot of new information on the malaria parasite have been discovered. Furthermore, enlightening efforts including "Malaria research home page" and "Malaria letter" contributed the promotion of the malaria research in Japan. Thus, achievement of this project is almost complete as initial plan.
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