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1998 Fiscal Year Final Research Report Summary

STUDY ON REAL-TIME MEASUREMENT OF CARDIAC MUSCLE VISCOELASTICITY USING AN ULTRASONIC TACTILE MICROSENSOR CATHETER

Research Project

Project/Area Number 08458296
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Biomedical engineering/Biological material science
Research InstitutionNATIONAL CARDIOVASCULAR CENTER RESEARCH INSTITUTE

Principal Investigator

TSUJI Takayuki  NATIONAL CARDIOVASCULAR CENTER RESEARCH INSTITUTE,DEPARTMENT, DIRECTOR, 実験治療開発部, 部長 (00075764)

Co-Investigator(Kenkyū-buntansha) OMATA Sadao  NIHON UNIVERSITY FACULTY OF ENGINEERING, PROFESSOR, 工学部, 教授 (90060186)
FUJISATO Toshia  NATIONAL CARDIOVASCULAR CENTER RESEARCH INSTITUTE, RESEARCHER, 実験治療開発部, 室員 (60270732)
MIYAWAKI Fujio  NATIONAL CARDIOVASCULAR CENTER RESEARCH INSTITUTE, CHIEF RESEARCHER, 実験治療開発部, 室長 (50174222)
Project Period (FY) 1996 – 1998
Keywordsultrasonic tactile sensor / resonant frequency shift / microtip catheter / viscoelasticity / beating heart muscle / in vivo organ viscoelasticity
Research Abstract

Aim of the project is to develop a tactile sensor catheter having 1.5 mm in diameter equipped with the 200 kHz ultrasonic microtip that can detect in real-time viscoelasticity change of beating heart muscle. Influence of contact pressure of the tip on the objects which are silicone rubber discs having various silicone contents from 40 to"90 % was studied by varying tip weight loaded with various sizes of lead chips from 5 to 100 g. Ultrasonic resonant frequency shift (DELTAf) depended on the tip load. Five gram load was decided appropriate for measuring soft tissues.
The negative DELTAf became bigger in softer material. Viscoelasticity measurements of in vivo organs including liver, kidney, spleen and muscles in anesthetized dogs revealed the DELTAf of muscle was smaller than other tissues. Skeletal muscle, kidney, liver and spleen were softer in order. Dynamic changes associated with the left ventricular wall motion was obtained by the catheter inserted via carotid artery However, the signals originating from viscoelasticity changes of the ventricular muscle and from the tip collision against the ventricular wall in systole cannot be discriminated. Improvement of the catheter should be necessary for this purpose.

  • Research Products

    (6 results)

All Other

All Publications (6 results)

  • [Publications] 村田正典辻 隆之、ほか: "超音波接触センサーによるイヌ 骨格筋虚血のリアルタイム評価" 日本機械学会第9回バイオエンジニアリング学術講演会. 210. 71-71 (1997)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Murata M, Tsuji T, et al: "Measurement of stiffness of silicon and in vivo organs with an ultrasonic tactile sensor" Proceedings of 3rd Far-Eastern Symposium on Biomedical Masterials. 103-103 (1997)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Murata M, Tsuji T, et al: "Measurement of stiffness of organs in vivo with an ultrasonic tactile sensor" Proceedngs of World Congress on Medical Physics and Biomadical Engineering. 132-132 (1997)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 村田 正典、辻 隆之、ほか: "超音波触覚カテーテルによるイヌ左室壁粘弾性のリアルタイム計測" 第34回日本ME学会. 63. 227-227 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 村田正典、辻 隆之、ほか: "リモートサージェリのための触覚センサーによるイヌin vivo臓器のリアルタイム評価" 第5回日本コンピュータ外科学会. VIII(5). 109-110 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Murata M, Tsuji T, Haibo R, Omata S.: "Measurement of stiffness of organs in vitro with an ultrasonic tactile sensor" Medical & Biological Engineering & Computing. Vol.35, Supplement Part I. 132 (1997)

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 1999-12-08  

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