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1997 Fiscal Year Final Research Report Summary

Development of integrated system of mental test and brain information analysis for diagnosis as well as treatment evaluation of language and thought disorders

Research Project

Project/Area Number 08558094
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section展開研究
Research Field Biomedical engineering/Biological material science
Research InstitutionUniversity of Tokyo

Principal Investigator

ITOH Kenji  University of Tokyo, Grad School Med, Assist Prof, 大学院・医学系研究科, 助手 (80010106)

Co-Investigator(Kenkyū-buntansha) KOSHIDA Ichiro  Tokyo Engineering Unieversity, Fac Eng, Assoc Prof, 工学部, 助教授 (00192055)
YUMOTO Masato  University of Tokyo, Med Hospital, Assist Prof, 医学部・付属病院, 助手 (30240170)
NAKAGOME Kazuyuki  University of Tokyo, Med Hospital, Assist Prof, 医学部・付属病院, 助手 (30198056)
FUKUDA Masato  University of Tokyo, Med Hospital, Lecturer, 医学部・付属病院, 講師 (20221533)
HIRAMATSU Kenichi  University of Tokyo, Med Hospital, Assist Prof, 医学部・付属病院, 助手 (50218814)
Project Period (FY) 1996 – 1997
KeywordsTopography / Mental function test / Thought disorder / Brain functional modules / Magnetoencephalography / Fast wave / Language function / Event-related Potentials
Research Abstract

We investigated and obtained following results on the development of integrated simultaneous acquisition system of test data and brain infomation of language, cognitive and mental functions for diagnosis as well as treatment evaluation of language and thought disorders.
1.We applied the feature extraction and correlation analysis method to brain functional data during language and thought processes in order to clarify the importance of coincident cerebral functional modules localized and associated by fast rhythmic activities.
2.We constructed a on-line task presenting system in order to test mental and language functions by computer-controlled audio-visual presentation.
3.We confirmed the applicability of data-base on mental test on normals and schizophrenics to subjective evaluation of language and thought disorders.
4.We elucidated the necessity of such as structure-function corresponding model between 3D object of brain massive and scalp surface object for final routine integrating test and analysis.
5.We confirmed the priority of network user interface by Java and moving data files by Quick Time 3.0 for interactive manipulation of multiple combined data in picture format.
6.We completed the integrated test and analysis system and examined the system for practical application to conclude that more than 128channel EEG/MEG data are necessary compared to recent high resolution fMRI and also that technique of multiple simultaneous measuring on brain functions should be established.

  • Research Products

    (15 results)

All Other

All Publications (15 results)

  • [Publications] Mazuka R.Itoh K.: "Processing down the garden path in Japanese:processing of sentences with lexical homonyms." Journal of Psycholinguistic Research. 26. 207-228 (1997)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Itoh K, Koshida I, Hiramatsu K, etal: "Topographic correnation analysis of event-related potentials and oscillations during linguistic and nonlinguistic porocesses" Electroencephalography and Clinical Neurophysiology. 103(S). 98-98 (1997)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Koshida I, Itoh K, Hiramatsu K, etal: "A high resolution time domain EEG visualization system for personal computer" Electroencephalography and Clinical Neurophysiology. 103(S). 114-114 (1997)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 福田 正人・畑 哲信・丹羽 真一・伊藤 憲治・他: "精神分裂病の思考障害" 電子情報通信学会技術研究報告. TL97-7. 17-29 (1997)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 中込 和幸・福田 正人・畑 哲信・伊藤 憲治・他: "精神分裂病におけるNd,MMNのscalp current density mapping の検討" 脳波と筋電図. 25. 195-195 (1997)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Itoh K, Nakagome K, Hiramatsu K, Koshida I: "Speech processing and the brain" Proceedings of the Workshop on Thought and Language. 1-8 (1997)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 丹羽 真一・鶴 紀子・伊藤 憲治・他: "事象関連電位:事象関連電位と情報科学の発展" 新興医学出版, 205 (1997)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Mazuka R,Itoh K,Kondo T: "Processing down the garden path in Japanese : processing of sentences with lexical homonyms" Journal of Psycholinguistic Research. 26. 207-228 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Itoh K,Koshida I,Hiramatsu K,Fukuda M et al: "Topographic correnation analysis of event-related potentials and oscillations during linguistic and nonlinguistic processes" Electroencephalography and Clinical Neuro-physiology. 103 (S). 98 (1977)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Koshida I,Itoh K,Hiramatsu K,Fukuda M,et al: "A high resolution time domain EEG visualization system for personal computer" Electroencephalography and Clinical Neuro-physiology. 103 (S). 114 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Fukuda M,Hata A,Niwa S,Itoh K,et al: "Thought disorders in schizophrenics" IEICE Technical Report. TL97-7. 17-29 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Nakagome K,Fukuda M,Hata A,Itoh K,et al: "Scalp current density mapping of Nd, MMN in schizophrenics" Jpn J EEG & EMG. 25. 195 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Koshida I,Itoh K,Hiramatsu K,Fukuda M,et al: "Evaluation of 2D topographic processing with multichannel EEG measuring system" Jpn J EEG & EMG. 25. 132 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Itoh K,Nakagome K,Hiramatsu K,Koshida I,et al: "Speech processing and the brain" Proceedings of the Workshop on Thought and Language. 1-8 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Niwa S,Tsuru N,Itoh K,et al: Event-Related Potentials and the Development of Information Science. Shiko-Igaku Shuppan-sha, 205 (1997)

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 1999-03-16  

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