1997 Fiscal Year Final Research Report Summary
Syntheses of Vinyl Monomers Having Fluorescence Probe Unit and Studies on Polymer Micro-Environments
| Project/Area Number |
08651052
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
高分子合成
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| Research Institution | Nara Women's University |
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Principal Investigator |
IWAI Kaoru Nara Women's Univ., Fac.of Sci., Associate Prof., 理学部, 助教授 (90127423)
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| Project Period (FY) |
1996 – 1997
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| Keywords | intramolecular fluorescence probe / intramolecular chargetransfer fluorescence / copolymer / thermosensitive polymer / temperature-induced phase transition / polymer micro-environments / poly(N-isopropylacrylamide) / LCST |
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| Research Abstract |
9-(4-N,N-Dimethylaminophenyl) phenanthrene (DMA-Phen ; DP), in which N,N-dimethylaniline (DMA) and phenanthrene (Phen) are linked directly by a Csp^2-Csp^2 bond, shows an intense and structureless intramolecular charge-transfer (ICT) fluorescence. We have been interedted in this compound DP as a new fluorescence probe because of its strong solvatochromism and studied polymer micro-environments with using DP as an intramolecular fluorescence probe. In this project a new vinyl monomer having DP unit was synthesized and termperature-induced phase transitions of some acrylamide derivative polymers in aqueous solutions have been studied by using the fluorescence of a DP probe incorporated into the polymers. The results in this study are as follows.
1. A new methyl methacrylate (MMA) derivative monomer having DP unit (DP=MMA) was synthesized.
2. Some DP-labeled acrylamide polymers such as poly(N-isoprophylacrylamide) (PNIPAM), poly(N-n-propylacrylamide) (PNNPAM), and poly(N-isoprophylmethacrylamide) (PNIPMAM) were prepared and their temperature-induced phase transitions and polymer micro-environments in aqueous solutions were studied by fluorescence probe technique.
3. DP-labeled PNIPAM copolymers with NNPAM and NIPMAM were prepared. The NIPAM copolymers exhibit their LCST between 19-46ﾟC,depending on their copolymer compositions. And their temperature-induced phase transitions appear to be very sharp as well as that of NIPAM homopolymer.
4. Fluorescence label studies of thermosensitive PNIPAM hydrogels are in progress.
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