The Effects of Day Treatment on Disabilities and Relapse Prevention of schizophrenia.

1998 Fiscal Year Final Research Report Summary

• Project/Area Number: 08671109
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Psychiatric science
• Research Institution: Teikyo University
• Principal Investigator: IKEBUCHI Emi Teikyo University School of Medicine, Department of Psychiatry, associate professor, 医学部, 助教授 (20246044)
• Co-Investigator(Kenkyū-buntansha): HIROSE Tetsuya Teikyo University School of Medicine, Department of Psychiatry, professor, 医学部, 教授 (10101742) ; SASAKI Takashi Teikyo University School of Medicine, Department of Psychiatry, Lecturer, 医学部, 助手 ; NUMAGUCHI Ryoichi Teikyo University School of Medicine, Department of Psychiatry, Lecturer, 医学部, 助手 (10307192)
• Project Period (FY): 1996 – 1998
• Keywords: pertial hospitalization / day treatment / schizophrenia / disability / psychiatric rehabilitation / relapse / disablement / community work shop

Research Abstract

Our hypothesis is that day treatment with optimal pharmacotherapy can improve disabilities and relapse rate of schizophrenia which will lead long term prognosis to be better. We had practiced training of evaluation for staff of seven day treatment centers and eight community workshops which co-operated with our research project in 1996. We registered new attendants of these facilities from January 1997 to December 1998. Now we are following 80 registered attendants for two years.
1, Subjects: 80 registered attendants were diagnosed with schizophrenia by their psychiatrists. Fifty-two cases were male. The average age was 33.8 year old. The average age of onset of schizophrenia was 24.0 year old. The average umber of previous hospitalization was 1.9.
2, Method: We evaluated subjects four times for two years: (1) at the start of the treatment of day treatment centers or community workshops, (2) half year from the start, (3) one year later, (4) two years later, Evaluation measures were the L ife Assessment Scale for persons with Mental Illness (LASMI), the Brief Psychiatric Rating Scale (BPRS), the WHO-QOL scale, and the Global Assessment Scale (GAS).
3, Results and Discussion: We have finished one-year follow up study only in 1/3 subjects, and we are now continuing follow-up study. Thus we reported results at the start point (n=80), half-year later (n=31), and one-year later (n=21). There was no significant difference of demographic features, LASMI, GAS, and WHO-QOL between the day treatment group and the community workshops group. At the point of half year later, the day treatment group showed significant improvement of Endurance/Stability subscale of LASMI than at the start point, and significant better score of Interpersonal relationship subscale and Work subscale of LASMI than the community workshops group. There was significant correlation between improvement of Daily living subscale of LSAMI and improvement of psychological subscale of WHO-QOL. At the point of one year later, the day treatment group showed significant improvement of Daily living subscale of LASMI than at the start point. Our conclusion was that some components of disabilities of schizophrenia (I.e. stability and daily living skills) could be improved by day treatment with change of subjective QOL.