1997 Fiscal Year Final Research Report Summary

Mechanism of circulatory support by cardiomyoplasty

Research Project

Project/Area Number	08671535
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Single-year Grants
Section	一般
Research Field	Thoracic surgery
Research Institution	Yokohama City University
Principal Investigator	KONDO Jiro Yokohama City University, School of Medicine, Associate Professor, 医学部, 助教授 (00046038)
Co-Investigator(Kenkyū-buntansha)	ISODA Susumu Yokohama City University, School of Medicine, Associate, 医学部, 助手 (40254172)
Project Period (FY)	1996 – 1997
Keywords	skeletal muscle / circulatory support / cardiomyoplasty
Research Abstract	We studied mechanism of circulatory support by cadiomyoplasty. We focused on changes of power output with the change of electrical stimulation protocol. From our study, identical frequency for cardiomyoplasty is around 20 Hz. Thirty Hz, that has been widely used for cardiomyoplasty electrical stimulation, seems to be higher than should be. We hypothized that clinical problems like muscle fatty degeneration or deterioration of muscle power in the long run is caused by exess of the stimulation frequency. Mechanism of circulatory support by cardiomyoplasty seems to be unloading of myocardial tension and decrease of oxygen consumption.

(7 results)