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1998 Fiscal Year Final Research Report Summary

An Experimental Study of the Hybrid Bone with Vascularized Periosteum

Research Project

Project/Area Number 08671683
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Orthopaedic surgery
Research InstitutionNara Medical Univ.

Principal Investigator

YAJIMA Hiroshi  Nara Medical Univ., Orthop.Surg., Lecturer, 医学部, 講師 (20221640)

Co-Investigator(Kenkyū-buntansha) TAMAI Susumu  Nara Medical Univ., Orthop.Surg., Professor, 医学部, 教授 (10075088)
Project Period (FY) 1996 – 1998
Keywordshydroxyapatite ceramics / vascularized tissue transplantation / periosteum / osteogenesis / bone marrow cells
Research Abstract

1. We made a model of the vascularized artificial bone, combined the periosteumn with the hydroxyapatite ceramics. We evaluated that the vascularized perioteum had an osteogenic capacity using Northen blotting.
2. We evaluated the postoperative neovascularization of the hydroxyapatite ceramics using microangiogram. It was no relationship between the vascular proliferation and the osteogenic capacity.
3. We made a new model of the vascularized artificial bone with bone marrow cells. We evaluated the osteogenic capacity histologically and biochemically. We found this model had an advantage of the rapid osteogenesis postoperatively.

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Published: 1999-12-08  

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