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1998 Fiscal Year Final Research Report Summary

Hybridization and Modification of Apatite-Collagen Composite Membranes

Research Project

Project/Area Number 08672233
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field 補綴理工系歯学
Research InstitutionOsaka University

Principal Investigator

OKAZAKI Masayuki  Osaka Univ.Fac.of Dent.Assoc.Prof., 歯学部, 助教授 (30107073)

Co-Investigator(Kenkyū-buntansha) MAEDA Yoshinobu  Osaka Univ.Fac.of Dent.Prof., 歯学部・附属病院, 教授 (10144510)
TAIRA Masayuki  Osaka Univ.Fac.of Dent.Assistant, 歯学部, 助手 (60179398)
TERAOKA Fumio  Osaka Univ.Fac.of Dent.Assistant, 歯学部, 助手 (00099805)
SOHMURA Taiji  Osaka Univ.Fac.of Dent.Assist.Prof., 歯学部, 講師 (10154692)
TAKAHASHI Junzo  Osaka Univ.Fac.of Dent.Prof., 歯学部, 教授 (80029149)
Project Period (FY) 1996 – 1998
KeywordsApatite / Collagen / Composite Membranes / Hybridization / Bioadhesion
Research Abstract

Recent focus in dentistry is how to reconstruct of lost teeth. Most people lose their teeth with age and must use artificial prosthetics such as dentures and artificial tooth roots. However, conventional dentures and implants are not satisfactory regarding appropriate fit onto the surface of the oral tissue. Furthermore, we have problems due to sense of taste and biomechanical properties. To solve such problems, we started to investigate the hybrid-type apatite-collagen composites with the noble functions similar to biological tissues. In addition, we made apatite-collagen composite membranes, which can be adhered to both hard and soft tissues. These membranes were successfully insolubilized by UV-irradiation and had suitable mechanical properties. When they were implanted into rat or rabbit, no significant inflammation was observed, and the membranes showed good biocompatibility and adhesive properties.

  • Research Products

    (10 results)

All Other

All Publications (10 results)

  • [Publications] Okazaki M: "Properties of heterogeneオus apatites containing magnesium,fluoride and carbonate" Adv.Dent.Res.10. 252-259 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Okazaki M: "Heterogeneous iron-containing fluoridated apatites" Biomaterials. 18. 11-14 (1997)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 岡崎正之: "アパタイト・コラーゲン複合ラミネート膜の不溶化と生体接着特性" 人工臓器. 26. 508-512 (1997)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Okazaki.M.: "Rietveld analysis and Fourier maps or hydroxyapatites" Biomaterials. 18. 795-799 (1997)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Okazaki,M.: "Differences in solubility of two types of heterogeneous fluoridated hydroxyapatites" Biomaterials. 19. 611-616 (1998)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Okazaki, M.: "Properties of heterogeneous apatites containing magnesium, fluoride, and carbonate." Adv.Dent.Res.10. 252-259 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Okazaki, M.: "Heterogeneous iron-containing fluoridated apatites." Biomaterials. 18. 11-14 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Okazaki, M.: "Insolubilization and bio-ahhesion properties of apatite-collagen composite laminate membranes (in Japanese)." Artificial Organ. 26. 508-512 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Okazaki, M.: "Rietveld analysis and Fourier maps of hydroxyapatites." Biomaterials. 18. 795-799 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Okazaki, M.: "Differences in solubility of two types of hetero geneous fluoridated hydroxyapatites." Biomaterials. 19. 611-616 (1998)

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 1999-12-08  

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