HISTOCHEMICAL AND ULTRASTRUCTURAL STUDIES ON THE MECHANISM OF OCCURRING IN FOOD ALLERGY

1997 Fiscal Year Final Research Report Summary

• Project/Area Number: 08680070
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: 家政学
• Research Institution: NAKAMURA GAKUEN JUNIOR COLLEGE
• Principal Investigator: MATSUGUMA Miki NAKAMURA GAKUENN JUNIOR COLLEGE,ASSISTANT, 食物栄養科, 助手 (40259669)
• Co-Investigator(Kenkyū-buntansha): FUJITA Mamoru NAKAMURA GAKUENN UNIVERSITY,PROFESSOR, 家政学部, 教授 (60037471)
• Project Period (FY): 1996 – 1997
• Keywords: FOOD ALLERGY / FOOD ANTIGEN / SMALL INTESTINE / HISOCHEMISTRY / UL TRANSTRUCTURE / MACROMOLECULE / 植物性レクチン

Research Abstract

Suckling animals are able to absorb meternal immunoglubulins from milk in the jejunal epithelial cells and to transport these proteins intact to the circulation. Wearing and adult animals, however, don't absorb macromolecules in the jejunal and ileal epitelial cells. To determine whether an inversion of food antigens at the initial stages of allergy occurred with absorption of maternal antibody, tracer, histochemistry, cytochemistry and ultrastructural studies were used in the small intestine of the suckling rats.
These results were suggested that food antigen and macromolecules invaded in connection with mechanism which maternal antibody transport across the jejunal absorptive cells in suckling rats.

Research Products

• [Publications] M.Fujita, R.Baba, T.Oshikawa and M.Miyoshi: "Relationship Between Endocytic Pathway and Cytoskeletons in Absorptive Cells of the Small Intestine of the Suckling Rat" Digestion & Absorption. 19・2. 86-90 (1996)
  • Description: 「研究成果報告書概要(和文)」より
• [Publications] T.Oshikawa, R.Baba, M.Fujita and M.Miyoshi: "Apical Endocytosis of Lectin by Absorptive Cells of Suckling Rats Jejunum in vivo" Okajimas Folia Anatomica Japan. 73・5. 229-246 (1996)
  • Description: 「研究成果報告書概要(和文)」より
• [Publications] 楠 喜久枝、藤田 守、松隈 美紀、馬場 良子、三成 由美、田所 忠弘、印南 敏、前川 昭男: "カキの葉組織構造並びに食物繊維成分について" 日本食品保蔵科学会誌. 23・2. 65-75 (1997)
  • Description: 「研究成果報告書概要(和文)」より
• [Publications] M.Fujita, R.Baba, M.Miki, T.Kai, S.Nozaki, and M.Miyoshi: "Apical and Basolateral Endocytic Pathways in Absorptive Cells of Suckling and Adult Rats Small Intestine in vivo" Digestion & Absorption. 20・2. 113-118 (1997)
  • Description: 「研究成果報告書概要(和文)」より
• [Publications] R.Baba, M.Fujita, M.Miki, T.Kai, S.Nozaki, and M.Miyoshi: "Endocytosis by Absorptive Cells of Adult Rats Large Intestine in vivo" Digestion & Absorption. 20・2. 129-132 (1997)
  • Description: 「研究成果報告書概要(和文)」より
• [Publications] Oshikawa, T., Baba, R., Fujita, M.and Miyoshi, M.: "Apical endocytosis of lectins by absorptive cells of suckling rat jejunum in vivo" Okajimas Folia Anatomica Japan. 73 (5). 229-246 (1996)
  • Description: 「研究成果報告書概要(欧文)」より
• [Publications] Fujita, M., Baba, R., Oshikawa, T.and Miyoshi, M.: "Relationship between endocytic pathway and cytoskeletons in absorptive cells of the small intestione of the suckling rat" Digestion & Absorption. 19 (2). 86-90 (1996)
  • Description: 「研究成果報告書概要(欧文)」より
• [Publications] Kusunoki, K., Fujita M., Matuguma M., Baba R., Minari Y., Tadokoro T., Innami S.and Maekawa A.: "Studies on Microscopic Observations of Tissue Structures and Dietary Fiber Components in Persimmon (Diospyros Kaki) Leaves" Journal of the Japan Association of Food preservation Scientists. 23 (2). 65-75 (1997)
  • Description: 「研究成果報告書概要(欧文)」より
• [Publications] Fujita, M., Baba, R., Matsuguma, M./, Kai, T., Nozaki, S.and Miyoshi, M.: "Apical and basolateral endocytic pathways in absorptive cells of suckling rat adult rats small intestine in vivo" Digestion & Absorption. 20 (2). 113-118 (1997)
  • Description: 「研究成果報告書概要(欧文)」より
• [Publications] Baba, R., Matsuguma, M., Fujita, M., Kai, T., Nozaki, S.and Miyoshi, M.: "Endocytosis by absorptive cells of the adult rats large intestine in vivo" Digestion & Absorption. 20 (2). 129-132 (1997)
  • Description: 「研究成果報告書概要(欧文)」より