1997 Fiscal Year Final Research Report Summary
HISTOCHEMICAL AND ULTRASTRUCTURAL STUDIES ON THE MECHANISM OF OCCURRING IN FOOD ALLERGY
Project/Area Number |
08680070
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
家政学
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Research Institution | NAKAMURA GAKUEN JUNIOR COLLEGE |
Principal Investigator |
MATSUGUMA Miki NAKAMURA GAKUENN JUNIOR COLLEGE,ASSISTANT, 食物栄養科, 助手 (40259669)
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Co-Investigator(Kenkyū-buntansha) |
FUJITA Mamoru NAKAMURA GAKUENN UNIVERSITY,PROFESSOR, 家政学部, 教授 (60037471)
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Project Period (FY) |
1996 – 1997
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Keywords | FOOD ALLERGY / FOOD ANTIGEN / SMALL INTESTINE / HISOCHEMISTRY / UL TRANSTRUCTURE / MACROMOLECULE / 植物性レクチン |
Research Abstract |
Suckling animals are able to absorb meternal immunoglubulins from milk in the jejunal epithelial cells and to transport these proteins intact to the circulation. Wearing and adult animals, however, don't absorb macromolecules in the jejunal and ileal epitelial cells. To determine whether an inversion of food antigens at the initial stages of allergy occurred with absorption of maternal antibody, tracer, histochemistry, cytochemistry and ultrastructural studies were used in the small intestine of the suckling rats. These results were suggested that food antigen and macromolecules invaded in connection with mechanism which maternal antibody transport across the jejunal absorptive cells in suckling rats.
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Research Products
(10 results)
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[Publications] Fujita, M., Baba, R., Matsuguma, M./, Kai, T., Nozaki, S.and Miyoshi, M.: "Apical and basolateral endocytic pathways in absorptive cells of suckling rat adult rats small intestine in vivo" Digestion & Absorption. 20 (2). 113-118 (1997)
Description
「研究成果報告書概要(欧文)」より
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[Publications] Baba, R., Matsuguma, M., Fujita, M., Kai, T., Nozaki, S.and Miyoshi, M.: "Endocytosis by absorptive cells of the adult rats large intestine in vivo" Digestion & Absorption. 20 (2). 129-132 (1997)
Description
「研究成果報告書概要(欧文)」より