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1998 Fiscal Year Final Research Report Summary

International Data Base for Human Brain Function

Research Project

Project/Area Number 09044250
Research Category

Grant-in-Aid for international Scientific Research

Allocation TypeSingle-year Grants
SectionJoint Research
Research Field Neuroscience in general
Research InstitutionTOHOKU UNIVERSITY

Principal Investigator

FUKUDA Hiroshi  Tohoku Univ., IDAC,Professor, 加齢医学研究所, 教授 (30125645)

Co-Investigator(Kenkyū-buntansha) KINOMURA Shigeo  Tohoku University, IDAC,Assistant Professor, 加齢医学研究所, 助手 (70281996)
KAWASHIMA Ryuta  Tohoku University, IDAC,Senior Assistant Professor, 加齢医学研究所, 講師 (90250828)
ZILLES Karl  C.& O.Vogt Brain Research Institute, Professor, C&OVog研究所, 教授
ROLAND Per  Karolinska Institute, Professor, 教授
Project Period (FY) 1997 – 1998
KeywordsComputerized Brain Atlas / human brain function / image database / Anatomical Normalization / PET / MRI
Research Abstract

1. Development and Evaluation of the Computerized Brain Atlas System
We validated the anatomical precision of spatial normalization with the Elastic Transformation System which has developed by Zilles's group with our collaboration. We found that this system shows high effectiveness in spatial normalization procedure compared with other systems, indicating that it can be used not only for positorn emission tomography (PET) activation studies but for functional magnetic resonance imaging (MRI) studies.
2. Functional Brain Mapping of Cognitive and Motor Function
Roland's group and our group participated this project. We used PET to investigate functional brain areas of humans involved in many kinds of cognitive or motor tasks. The results obtained are used as contents of the brain function database which has been developing by our group.
3. Development of International Brain Anatomy Database
We and Evans's group had a meeting in Montreal, and have agreed to create comparable international brain anatomy database with Zilles's group. We have decided to correct 300 3D-brain MRI of healthy subjects for each group, and to perform inter-ethnic comparisons using spatial normalization technique develped by Evans's group. Our group already corrected 150 brain MRIs, and we have estimated standard brain anatomy of the Japanese population of different age group from this data.

  • Research Products

    (11 results)

All Other

All Publications (11 results)

  • [Publications] Kawashima R: "Selective visual and auditory attention towards utterances -A PET study-" Neuroimage. in press. (1999)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Kawashima R: "A positron emission tomography study of self-paced finger movements at different frequencies" Neuroscience. in press. (1999)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Kawashima R: "The human amygdala plays an important role in gaze monitoring-A PET study-" Brain. in press. (1999)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Kawashima R: "Oculomotor sequence learning : A positron emission tomography study" Exp Brain Res. 122. 1-8 (1998)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Roland PE: "Shape and roughness activate different somatosensory areas in the human brain" Proc Acad Sci USA. 95. 3295-3300 (1998)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Kawashima R: "Regional cerebral blood now changes in human brain related to ipsilateral and contralateral complex handmovements-A PET study-" Eur J Neurosci. 10. 2254-2260 (1998)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Kawashima R,et al.: "Selective visual and auditory attention towards utterances -A PET study-" Neuroimage. (in press). (1999)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Kawashima R,et al.: "A positron emission tomography study of self-paced finger movements at different frequencies" Neuroscience. (in press). (1999)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Kawashima R,et al.: "Oculomotor sequence learning : A positron emission tomography study" Exp.Brain.Res.122. 1-8 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Roland PE,et al.: "Shape and roughness avtivate different somatosensory areas in the human brain" Proc.Natl.Acad.Sci.USA. 95. 3295-3300 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Kawashima R,et al.: "Regional cerebral blood flow changes in human brain related to ipsilateral and contralateral complex hand movements -A PET study-" Eur.J.Neurosci.10. 2254-2260 (1998)

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 1999-12-08  

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